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Results for "

skeleton

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Amino Acid Decarboxylase (1) Antibiotic (1) Apoptosis (3) Bacterial (10) BCRP (2) Biochemical Assay Reagents (7) Calmodulin (1) Cholinesterase (ChE) (2) Cytochrome P450 (1) DNA/RNA Synthesis (2) Drug Derivative (2) Drug Intermediate (13) Endogenous Metabolite (18) Enterovirus (1) Estrogen Receptor/ERR (2) Farnesyl Transferase (3) Ferroptosis (1) Flavivirus (1) Fluorescent Dye (3) Fungal (3) Glutaminase (1) GSK-3 (1) Histamine Receptor (1) Histone Acetyltransferase (1) HIV (1) Isotope-Labeled Compounds (8) JAK (1) Liposome (2) Microtubule/Tubulin (1) MOFs (1) NO Synthase (2) Nuclear Factor of activated T Cells (NFAT) (2) Nucleoside Antimetabolite/Analog (1) Orexin Receptor (OX Receptor) (1) Parasite (1) Phosphodiesterase (PDE) (1) Phytohormone (1) Radionuclide-Drug Conjugates (RDCs) (1) Reactive Oxygen Species (ROS) (1) Reference Standards (8) TGF-β Receptor (1) TNF Receptor (1) Tyrosinase (13) β-catenin (1)
By Research Areas:	Cancer (25) Cardiovascular Disease (2) Endocrinology (1) Infection (17) Inflammation/Immunology (17) Metabolic Disease (22) Neurological Disease (15)
Oligonucleotides:	Antisense Oligonucleotides (1) Cholesterol (2)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

GMP Molecules

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W013636

2-Ketoglutaric acid Maximum Cited Publications 6 Publications Verification Alpha-Ketoglutaric acid; 2-Oxoglutaric acid	Tyrosinase Endogenous Metabolite	Neurological Disease Metabolic Disease
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013636S

2-Ketoglutaric acid-13C5 Alpha-Ketoglutaric acid-¹³C₅	Isotope-Labeled Compounds Tyrosinase Endogenous Metabolite	Neurological Disease Metabolic Disease
2-Ketoglutaric acid- ¹³C₅ (Alpha-Ketoglutaric acid- ¹³C₅) is a ¹³C labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-125598

Secologanin	Drug Intermediate	Others
Secologanin is an iridoid monoterpenoid glucoside found in the leaves of Lonicera tatarica and a key precursor for thousands of natural monoterpenoid alkaloids .

HY-W013636A

2-Ketoglutaric acid Sodium Maximum Cited Publications 6 Publications Verification Alpha-Ketoglutaric acid Sodium	Tyrosinase Endogenous Metabolite	Neurological Disease Metabolic Disease
2-Ketoglutaric acid Sodium (Alpha-Ketoglutaric acid Sodium) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013040

Pyrazine 1,4-Diazine	MOFs Drug Intermediate	Cardiovascular Disease Infection Inflammation/Immunology Cancer
Pyrazine is an aromatic nitrogen-containing heterocyclic compound with two nitrogen atoms, and is well known for its electron-deficient property. Pyrazine serves as a key pharmacophore in a variety of drugs, and also acts as the core skeleton of derivatives with anticancer, antimycobacterial, antithrombotic and anti-inflammatory activities .

HY-121388

Ledol (+)-Ledol	Fungal	Infection
Ledol ((+)-Ledol) is an antifungal agent isolated from the volatile oil components of Rhododendron tomentosum. Ledol also acts as an expectorant and antitussive, while it can cause adverse reactions such as dizziness, nausea and vomiting .

HY-W016349

Chelidamic acid	Amino Acid Decarboxylase	Others
Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid has good coordination ability with noble metal ions. Chelidamic acid is also one of the most potent inhibitors of glutamate decarboxylase, with a K_i of 33 μM.

HY-Y0135

Tropinone	Drug Intermediate	Cancer
Tropinone is an organic synthesis intermediate and a skeleton for constructing derivatives containing thiazole rings and other structures. Tropinone derivatives have anticancer activities such as inducing tumor cell apoptosis and inhibiting tyrosinase activity, and can be used in research such as anticancer drug development and tyrosinase inhibitor design .

HY-N0656

Usnic acid 2 Publications Verification	Bacterial DNA/RNA Synthesis Nuclear Factor of activated T Cells (NFAT) Apoptosis	Infection Inflammation/Immunology Cancer
Usnic acid is a secondary metabolite of lichens with a unique dibenzofuran skeleton. Usnic acid inhibits DNA/RNA synthesis and has antibacterial activity. Usnic acid induces cell cycle arrest and apoptosis and has anticancer activity. Usnic acid inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1. Usnic acid has antioxidant and anti-inflammatory activities by inhibiting lipid peroxidation and myeloperoxidase .

HY-P2733

Glycerol-3-phosphate oxidase, E. coli 2 Publications Verification GPO	Endogenous Metabolite Bacterial	Infection Metabolic Disease
Glycerol-3-phosphate oxidase, E. coli (GPO) is a key intermediate in glycerol metabolism. Glycerol-3-phosphate oxidase, E. coli is the skeleton of phospholipids in membrane lipids, and also a substrate in the respiratory chain. Glycerol-3-phosphate oxidase, E. coli produces electrons through oxidation. Glycerol-3-phosphate oxidase, E. coli is an enzyme with important functions in the field of biochemistry, and is widely used in medical testing and scientific research .

HY-W013636B

Calcium 2-oxoglutarate Maximum Cited Publications 6 Publications Verification	Tyrosinase Endogenous Metabolite	Metabolic Disease
Calcium 2-oxoglutarate is an intermediate in the production of ATP or GTP in the Krebs cycle. Calcium 2-oxoglutarate also acts as the major carbon skeleton for nitrogen-assimilatory reactions. Calcium 2-oxoglutarate is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013636C

2-Ketoglutaric acid potassium 5+ Cited Publications Alpha-Ketoglutaric acid potassium	Tyrosinase Endogenous Metabolite TNF Receptor	Neurological Disease Metabolic Disease
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) (potassium) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid potassium is a reversible and orally active inhibitor of tyrosinase with an IC₅₀ value of 15 mM. 2-Ketoglutaric acid potassium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid potassium significantly suppresses abnormal intestinal permeability, delocalization of tight junction proteins from the intestinal cells, expression of TNFα in vitro and in vivo. 2-Ketoglutaric acid potassium directly binds to TAK1, and inhibits the TRAF6-TAK1 interaction. 2-Ketoglutaric acid potassium also alleviates inflammatory bowel disease (IBD) symptoms and gut microbiota dysbiosis, evident by the improvements in the intestine length .

HY-U00190

Deprodone propionate RD20000	Bacterial	Inflammation/Immunology
Deprodone propionate (RD20000) is a corticosteroid which is obtained by esterifying with propionic acid the 17-position of the prednisolone skeleton and deoxidating its 21-position.

HY-N0829

Shionone 1 Publications Verification	Others	Inflammation/Immunology
Shionone is the major triterpenoid isolated from Aster tataricus, has anti-tussive, anti-inflammatory activities . Shionone possesses a unique six-membered tetracyclic skeleton and 3-oxo-4-monomethyl structure .

HY-N2920

β-Amyrenonol 11-Oxo-β-amyrin	Cytochrome P450	Inflammation/Immunology Cancer
β-Amyrenonol (11-Oxo-β-amyrin), an oleanolic-type triterpenoid in licorice roots, is a precursor of Glycyrrhetinic acid. β-Amyrenonol has anti-proliferative and anti-inflammatory activities, and β-Amyrenonol could function as the skeleton for the synthesis of many triterpenoids .

HY-W013636S1

2-Ketoglutaric acid-d4 Alpha-Ketoglutaric acid-d₄	Isotope-Labeled Compounds Tyrosinase Endogenous Metabolite	Neurological Disease Metabolic Disease
2-Ketoglutaric acid-d₄ (Alpha-Ketoglutaric acid-d₄) is the deuterium labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid Sodium is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W007771

Acridone	Bacterial BCRP	Infection Cancer
Acridone is an organic compound based on the acridine skeleton. Acridone has antibacterial, antimalarial, antiviral and anti neoplastic activities .

HY-133970

5α-Cholestane	Biochemical Assay Reagents Drug Intermediate	Metabolic Disease
5α-Cholestane is a skeleton. 5α-Cholestane can be used in the synthesis of Brassinosteroids. 5α-Cholestane can be used in skeletal muscle research .

HY-W013636R

2-Ketoglutaric acid (Standard) Maximum Cited Publications 6 Publications Verification Alpha-Ketoglutaric acid (Standard); 2-Oxoglutaric acid (Standard)	Reference Standards Tyrosinase Endogenous Metabolite	Neurological Disease Metabolic Disease
2-Ketoglutaric acid (Standard) (Alpha-Ketoglutaric acid (Standard)) is the analytical standard of 2-Ketoglutaric acid (HY-W013636). This product is intended for research and analytical applications. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013636S3

2-Ketoglutaric acid-13C Alpha-Ketoglutaric acid-¹³C	Isotope-Labeled Compounds Endogenous Metabolite Tyrosinase	Neurological Disease Metabolic Disease
2-Ketoglutaric acid- ¹³C (Alpha-Ketoglutaric acid- ¹³C) is a ¹³C labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W115609

N-Phenylbenzamide N-Benzoylaniline	Enterovirus Biochemical Assay Reagents	Infection Cancer
N-Phenylbenzamide (N-Benzoylaniline) is a compound skeleton. N-Phenylbenzamide can be used for the researches of cancer and infection, such as enterovirus and cervical cancer .

HY-121162

Mesembrine (+)-Mesembrine	5-HT Receptor Phosphodiesterase (PDE)	Neurological Disease
Mesembrine ((+)-Mesembrine) a main alkaloid that features an aryloctahydroindole skeleton. Mesembrine is a 5-HT transporter inhibitor with a K_i of 1.4 nM. Mesembrine also inhibits phosphodiesterase 4B (PDE4B) with an IC₅₀ of 7.8 μM .

HY-W006187

2-Amino-2-(p-tolyl)acetic acid (Rac)-H-Phg(4-Me)-OH	Glutaminase	Cancer
2-Amino-2-(p-tolyl)acetic acid is used for optimizing azide skeleton, and is the intermediate in the synthesis of 1,3, 4-thiadiazole compounds. 1,3,4-thiadiazole compounds exhibit potential anti-cancer activity, and inhibit glutaminase (GLSI) .

HY-W013636S2

2-Ketoglutaric acid-d6 Alpha-Ketoglutaric acid-d₆	Tyrosinase Endogenous Metabolite Isotope-Labeled Compounds	Neurological Disease Metabolic Disease
2-Ketoglutaric acid-d₆ (Alpha-Ketoglutaric acid-d₆) is the deuterium labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-N7293

Bakkenolide D	Histamine Receptor	Inflammation/Immunology
Bakkenolide D is a sesquiterpene lactone. Bakkenolide D is the major component of Bakkenolides in Petasites tricholobus. Bakkenolide D exhibits anti-allergic and antihistamine activities, and can be used in studies related to allergic rhinitis .

HY-W013973

p-Terphenyl	Drug Intermediate	Inflammation/Immunology Cancer
p-Terphenyl is a skeleton. p-Terphenyl derivatives have anticancer activity against liver cancer and pancreatic cancer. p-Terphenyl derivatives also have anti-inflammatory effects .

HY-N6894A

Pseudocoptisine chloride Isocoptisine chloride	Cholinesterase (ChE)	Inflammation/Immunology
Pseudocoptisine (Isocoptisine) chloride is a quaternary alkaloid with benzylisoquinoline skeleton, was isolated from Corydalis Tuber. Pseudocoptisine chloride inhibits acetylcholinesterase (AChE) activity with an IC₅₀ of 12.8 μM. Anti-inflammatory and anti-amnestic effects .

HY-W008388

Bz-rA N6-Benzoyladenosine	Nucleoside Antimetabolite/Analog	Others
Bz-rA (N6-Benzoyladenosine) is a nucleoside derivative with an N6 protecting group. Bz-rA is mainly used as a synthetic intermediate to participate in photocatalytic oxidative cyclization reactions and synthesize oligoribonucleotides. Bz-rA can be used to efficiently construct heterocyclic skeletons in photochemical conversions and protect the ribose moiety to regulate the cyclization pathway .

HY-133209

Fischeria A	Others	Cancer
Fischeria A is a norditerpene lactone of a new carbon skeleton, can be isolated from Euphorbia fischeriana .

HY-P2733B

Glycerol 3-phosphate Oxidase, Aerococcus viridans GPO, Aerococcus viridans	Endogenous Metabolite	Metabolic Disease
Glycerol-3-phosphate oxidase, Aerococcus viridans (GPO, Aerococcus viridans) is a key intermediate in glycerol metabolism. Glycerol-3-phosphate oxidase is the skeleton of phospholipids in membrane lipids, and also a substrate of respiratory chain. Glycerol-3-phosphate oxidase produces electrons through oxidation .

HY-P2733A

Glycerol 3-phosphate Oxidase, Pedio coccus sp. GPO, Pedio coccus sp.	Endogenous Metabolite	Metabolic Disease
Glycerol-3-phosphate oxidase, Pedio coccus sp. (GPO, Pedio coccus sp.) is a key intermediate in glycerol metabolism. Glycerol-3-phosphate oxidase is the skeleton of phospholipids in membrane lipids, and also a substrate in the respiratory chain. Glycerol-3-phosphate oxidase produces electrons through oxidation .

HY-N0656R

Usnic acid (Standard)	Reference Standards Bacterial DNA/RNA Synthesis Nuclear Factor of activated T Cells (NFAT) Apoptosis	Infection Inflammation/Immunology Cancer
Usnic acid is a secondary metabolite of lichens with a unique dibenzofuran skeleton. Usnic acid inhibits DNA/RNA synthesis and has antibacterial activity. Usnic acid induces cell cycle arrest and apoptosis and has anticancer activity. Usnic acid inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1. Usnic acid has antioxidant and anti-inflammatory activities by inhibiting lipid peroxidation and myeloperoxidase .

HY-155705

BMP agonist 1	TGF-β Receptor GSK-3 β-catenin	Others
BMP agonist 1 (compound 2 b) is a small-molecule agonist of bone morphogenic protein (BMP). BMP induces C2C12 cell differentiation with BMP and highly depends on active BMP signaling. BMP agonist 1 inhibits GSK3β, increases β-catenin signaling and synergistically regulates Id2and Id3 expression. BMP agonist 1 is used in diseases and defects of the skeleton research .

HY-W013636S4

2-Ketoglutaric acid-13C2 Alpha-Ketoglutaric acid-¹³C₂	Isotope-Labeled Compounds Tyrosinase Endogenous Metabolite	Neurological Disease Metabolic Disease
2-Ketoglutaric acid- ¹³C₂ (Alpha-Ketoglutaric acid- ¹³C₂) is a ¹³C labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-136473

CTX-0124143	Histone Acetyltransferase	Cancer
CTX-0124143 is a KAT6A inhibitor with a sulfonyl hydrazine skeleton .

HY-135324

4,4'-Iminodiphenol	Estrogen Receptor/ERR	Endocrinology
4-Propionamidophenol (compound 4a) is an inactive estrogen receptor ligand based on the diphenylamine skeleton .

HY-W006474

γ-Carboline 5H-Pyrido[4,3-b]indole	Flavivirus Drug Intermediate	Infection Cancer
γ-Carboline is a skeleton and antiviral agent. γ-Carboline shows anti-BVDV activity, with an EC₅₀  of  2.0  μM. γ-Carboline derivatives show anti-BVDV, antibacterial, antifungal, antitumor activity .

HY-N10697

Angulatin G Celangulatin E	Parasite	Infection
Angulatin G (Celangulatin E) is an insecticidal sesquiterpene polyol ester with a β-dihydroagarofuran sesquiterpene skeleton, which can be isolated from the root bark of Celastrus angulatus. Angulatin G shows LD₅₀ against Mythimna separata of 1656.4 μg/mL .

HY-151109

IR-990	Fluorescent Dye	Others
IR-990 is an activatable NIR-II fluorescent probe with an acceptor-π-acceptor (A-π-A) skeleton for real-time detection of H₂O₂ in vivo. IR-990 is a powerful diagnosis of agent-induced liver injury (DILI) .

HY-163634

YZK-C22	Fungal	Infection
YZK-C22, containing a 1,2,3-thiadiazol-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole skeleton, is a fungicide lead compound with broad-spectrum fungicidal activity .

HY-167629

Gibberellenic acid	Phytohormone Drug Intermediate	Others
Gibberellenic acid is an intermediate gibberellin compound with a tetracyclic diterpenoid skeleton, and can be generated by thermal decomposition of Gibberellic acid (GA₃, HY-N1964) in aqueous solution. Gibberellenic acid is thermally unstable in water and can further convert into allogibberic acid (approximately 80%) and 9-epiallogibberic acid (approximately 10%). It plays an important role in the degradation pathway and structural elucidation of Gibberellins .

HY-N3411

Labd-13(E)-ene-8α,15-diol 13E-Labdene-8α,15-diol; Copal-8α,15-diol	Others	Others
Labd-13(E)-ene-8α,15-diol is a diterpene with the labdane skeleton which can be extracted from Cistus symphytijbfolius .

HY-W013636AR

2-Ketoglutaric acid Sodium (Standard) Alpha-Ketoglutaric acid Sodium (Standard)	Reference Standards Tyrosinase Endogenous Metabolite	Neurological Disease Metabolic Disease
2-Ketoglutaric acid (Sodium) (Standard) is the analytical standard of 2-Ketoglutaric acid Sodium (HY-W013636A). This product is intended for research and analytical applications. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) Sodium (Standard) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013636AG

2-Ketoglutaric acid Sodium Alpha-Ketoglutaric acid Sodium	Tyrosinase Endogenous Metabolite	Neurological Disease Metabolic Disease
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) Sodium (GMP) is 2-Ketoglutaric acid Sodium (HY-W013636A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. 2-Ketoglutaric acid Sodium is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-N2528

Usnic acid sodium	Bacterial	Infection Cancer
Usnic acid sodium, a lichen-derived secondary metabolite, has a unique dibenzofuran skeleton. Usnic acid sodium has excellent anticancer and antimicrobial properties. Usnic acid sodium significantly inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1 .

HY-N11896

10-Hydroxyaloin B	Others	Inflammation/Immunology
10-Hydroxyaloin B is a bioactive oxanthrone based on the aloin skeleton .

HY-N14937

Albaflavenone	Antibiotic Bacterial Fungal	Infection
Albaflavenone is a sesquiterpene antibiotic with a zizaene skeleton. Albaflavenone is active against Bacillus subtilis .

HY-N13874

Andrastin B	Farnesyl Transferase	Cancer
Andrastin C is a protein farnesyltransferase inhibitor. Andrastin C has a common androstane skeleton .

HY-N9604

Andrastin C	Farnesyl Transferase	Cancer
Andrastin B is a protein farnesyltransferase inhibitor. Andrastin B has a common androstane skeleton .

HY-N1303

Shoreic acid Shoric acid	Others	Others
Shoreic acid (compound 8a) is a dammarane skeleton compound isolated from Cabralea eichleriana DC .

Cat. No.	Product Name	Type

HY-W013636AG

2-Ketoglutaric acid Sodium

Alpha-Ketoglutaric acid Sodium

Fluorescent Dye

2-Ketoglutaric acid (Alpha-Ketoglutaric acid) Sodium (GMP) is 2-Ketoglutaric acid Sodium (HY-W013636A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. 2-Ketoglutaric acid Sodium is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-D3250

PYSNO

Fluorescent Dye

PYSNO is a lysosome-targeted fluorescent probe based on a pyridazinone skeleton (λ_em=515-565 nm, λ_ex=405 nm) that can be used to track nitric oxide (NO) production in vivo. PYSNO exhibits a rapid, highly sensitive and highly selective "turn-on" response to endogenous and exogenous NO by blocking photoinduced electron transfer and regulating radiative decay rates. PYSNO enables precise in vivo monitoring in a mouse model of myocardial fibrosis and can be applied to the research of related diseases .

HY-D3224

HCP

Fluorescent Dye

HCP is a two-photon fluorescent probe capable of crossing the blood-brain barrier, which is specifically designed for real-time detection of hypochlorous acid (HClO/ClO ^-) produced by myeloperoxidase (MPO). Chlorination of the quinoline skeleton of HCP generates HCP-Cl, which eliminates intramolecular charge transfer (ICT) quenching and thereby produces fluorescence. HCP is suitable for in vivo dynamic imaging of HClO in the brains of epileptic mice and high-throughput screening of antiepileptic drugs (HCP-Cl: Ex/Em = 800 nm/495 nm) .

Cat. No.	Product Name	Type

HY-W013636C

2-Ketoglutaric acid potassium

5+ Cited Publications

Alpha-Ketoglutaric acid potassium

Biochemical Assay Reagents

2-Ketoglutaric acid (Alpha-Ketoglutaric acid) (potassium) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid potassium is a reversible and orally active inhibitor of tyrosinase with an IC₅₀ value of 15 mM. 2-Ketoglutaric acid potassium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid potassium significantly suppresses abnormal intestinal permeability, delocalization of tight junction proteins from the intestinal cells, expression of TNFα in vitro and in vivo. 2-Ketoglutaric acid potassium directly binds to TAK1, and inhibits the TRAF6-TAK1 interaction. 2-Ketoglutaric acid potassium also alleviates inflammatory bowel disease (IBD) symptoms and gut microbiota dysbiosis, evident by the improvements in the intestine length .

HY-133970

5α-Cholestane	Biochemical Assay Reagents
5α-Cholestane is a skeleton. 5α-Cholestane can be used in the synthesis of Brassinosteroids. 5α-Cholestane can be used in skeletal muscle research .

HY-W115609

N-Phenylbenzamide N-Benzoylaniline	Biochemical Assay Reagents
N-Phenylbenzamide (N-Benzoylaniline) is a compound skeleton. N-Phenylbenzamide can be used for the researches of cancer and infection, such as enterovirus and cervical cancer .

HY-W013973

p-Terphenyl	Biochemical Assay Reagents
p-Terphenyl is a skeleton. p-Terphenyl derivatives have anticancer activity against liver cancer and pancreatic cancer. p-Terphenyl derivatives also have anti-inflammatory effects .

HY-W013636AG

2-Ketoglutaric acid Sodium

Alpha-Ketoglutaric acid Sodium

Biochemical Assay Reagents

HY-W013973R

p-Terphenyl (Standard)	Biochemical Assay Reagents
p-Terphenyl (Standard) is the analytical standard of p-Terphenyl. This product is intended for research and analytical applications. p-Terphenyl is a skeleton. p-Terphenyl derivatives have anticancer activity against liver cancer and pancreatic cancer. p-Terphenyl derivatives also have anti-inflammatory effects .

HY-133970R

5α-Cholestane (Standard)	Biochemical Assay Reagents
5α-Cholestane (Standard) is the analytical standard of 5α-Cholestane (HY-133970). This product is intended for research and analytical applications. 5α-Cholestane is a skeleton. 5α-Cholestane can be used in the synthesis of Brassinosteroids. 5α-Cholestane can be used in skeletal muscle research .

Cat. No.	Product Name	Target	Research Area

HY-W006187

2-Amino-2-(p-tolyl)acetic acid (Rac)-H-Phg(4-Me)-OH	Glutaminase	Cancer
2-Amino-2-(p-tolyl)acetic acid is used for optimizing azide skeleton, and is the intermediate in the synthesis of 1,3, 4-thiadiazole compounds. 1,3,4-thiadiazole compounds exhibit potential anti-cancer activity, and inhibit glutaminase (GLSI) .

HY-P4948

Coumarin-Phalloidin	Biochemical Assay Reagents	Others
Coumarin-phalloidin is a kind of phalloidin labeled with Coumarin (HY-N0709). Coumarin-phalloidin is a new type of actin probe that can be used for triple immunofluorescence microscopic observation of the cell skeleton .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W013636

2-Ketoglutaric acid Maximum Cited Publications 6 Publications Verification Alpha-Ketoglutaric acid; 2-Oxoglutaric acid	Immune System Disorder Microorganisms Classification of Application Fields Anti-aging Ketones, Aldehydes, Acids Disease markers Other Diseases Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Source Classification	Tyrosinase Endogenous Metabolite
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-125598

Secologanin	Structural Classification Caprifoliaceae Iridoids Classification of Application Fields Lonicera japonica Thunb. Terpenoids Other Diseases Plants Disease Research Fields Source Classification	Drug Intermediate
Secologanin is an iridoid monoterpenoid glucoside found in the leaves of Lonicera tatarica and a key precursor for thousands of natural monoterpenoid alkaloids .

HY-W013636A

2-Ketoglutaric acid Sodium Maximum Cited Publications 6 Publications Verification Alpha-Ketoglutaric acid Sodium	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Tyrosinase Endogenous Metabolite
2-Ketoglutaric acid Sodium (Alpha-Ketoglutaric acid Sodium) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-121388

Ledol (+)-Ledol	Structural Classification Terpenoids Sesquiterpenes Ericaceae Plants Rhododendron tomentosum Harmaja Source Classification	Fungal
Ledol ((+)-Ledol) is an antifungal agent isolated from the volatile oil components of Rhododendron tomentosum. Ledol also acts as an expectorant and antitussive, while it can cause adverse reactions such as dizziness, nausea and vomiting .

HY-N0656

Usnic acid 2 Publications Verification	Infection Natural Products Classification of Application Fields Usnea diffracta Vain. Sunscreen Phenols Polyphenols Cosmetic Research Plants Disease Research Fields Usneaceae Source Classification	Bacterial DNA/RNA Synthesis Nuclear Factor of activated T Cells (NFAT) Apoptosis
Usnic acid is a secondary metabolite of lichens with a unique dibenzofuran skeleton. Usnic acid inhibits DNA/RNA synthesis and has antibacterial activity. Usnic acid induces cell cycle arrest and apoptosis and has anticancer activity. Usnic acid inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1. Usnic acid has antioxidant and anti-inflammatory activities by inhibiting lipid peroxidation and myeloperoxidase .

HY-W013636B

Calcium 2-oxoglutarate Maximum Cited Publications 6 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Tyrosinase Endogenous Metabolite
Calcium 2-oxoglutarate is an intermediate in the production of ATP or GTP in the Krebs cycle. Calcium 2-oxoglutarate also acts as the major carbon skeleton for nitrogen-assimilatory reactions. Calcium 2-oxoglutarate is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-N0829

Shionone 1 Publications Verification	Classification of Application Fields Terpenoids Diterpenoids Plants Compositae Sesbania vesicaria (Jacq.) Elliott Inflammation/Immunology Disease Research Fields	Others
Shionone is the major triterpenoid isolated from Aster tataricus, has anti-tussive, anti-inflammatory activities . Shionone possesses a unique six-membered tetracyclic skeleton and 3-oxo-4-monomethyl structure .

HY-N2920

β-Amyrenonol 11-Oxo-β-amyrin	Triterpenes Structural Classification Classification of Application Fields Terpenoids Myrtaceae Rhodomyrtus tomentosa Plants Pentacyclic Triterpenoids Inflammation/Immunology Disease Research Fields Source Classification	Cytochrome P450
β-Amyrenonol (11-Oxo-β-amyrin), an oleanolic-type triterpenoid in licorice roots, is a precursor of Glycyrrhetinic acid. β-Amyrenonol has anti-proliferative and anti-inflammatory activities, and β-Amyrenonol could function as the skeleton for the synthesis of many triterpenoids .

HY-W007771

Acridone	Infection Natural Products other families Classification of Application Fields Plants Disease Research Fields Source Classification	Bacterial BCRP
Acridone is an organic compound based on the acridine skeleton. Acridone has antibacterial, antimalarial, antiviral and anti neoplastic activities .

HY-W013636R

2-Ketoglutaric acid (Standard) Maximum Cited Publications 6 Publications Verification Alpha-Ketoglutaric acid (Standard); 2-Oxoglutaric acid (Standard)	Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Source Classification	Reference Standards Tyrosinase Endogenous Metabolite
2-Ketoglutaric acid (Standard) (Alpha-Ketoglutaric acid (Standard)) is the analytical standard of 2-Ketoglutaric acid (HY-W013636). This product is intended for research and analytical applications. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-121162

Mesembrine (+)-Mesembrine	Alkaloids Structural Classification other families Pyrrole Alkaloids Plants Source Classification	5-HT Receptor Phosphodiesterase (PDE)
Mesembrine ((+)-Mesembrine) a main alkaloid that features an aryloctahydroindole skeleton. Mesembrine is a 5-HT transporter inhibitor with a K_i of 1.4 nM. Mesembrine also inhibits phosphodiesterase 4B (PDE4B) with an IC₅₀ of 7.8 μM .

HY-N7293

Bakkenolide D	Structural Classification Natural Products Valeriana jatamansi Jones Plants Valerianaceae Source Classification	Histamine Receptor
Bakkenolide D is a sesquiterpene lactone. Bakkenolide D is the major component of Bakkenolides in Petasites tricholobus. Bakkenolide D exhibits anti-allergic and antihistamine activities, and can be used in studies related to allergic rhinitis .

HY-N6894A

Pseudocoptisine chloride Isocoptisine chloride	Alkaloids Piperidine Alkaloids Classification of Application Fields Plants Isoquinoline Alkaloids Disease Research Fields Inflammation/Immunology Papaveraceae Source Classification Corydalis turtschaninovii Bess.	Cholinesterase (ChE)
Pseudocoptisine (Isocoptisine) chloride is a quaternary alkaloid with benzylisoquinoline skeleton, was isolated from Corydalis Tuber. Pseudocoptisine chloride inhibits acetylcholinesterase (AChE) activity with an IC₅₀ of 12.8 μM. Anti-inflammatory and anti-amnestic effects .

HY-133209

Fischeria A	Terpenoids Diterpenoids Euphorbiaceae Plants Euphorbia kansuensis Prokh. Source Classification	Others
Fischeria A is a norditerpene lactone of a new carbon skeleton, can be isolated from Euphorbia fischeriana .

HY-N0656R

Usnic acid (Standard)	Structural Classification Natural Products Usnea diffracta Vain. Phenols Polyphenols Plants Usneaceae Source Classification	Reference Standards Bacterial DNA/RNA Synthesis Nuclear Factor of activated T Cells (NFAT) Apoptosis
Usnic acid is a secondary metabolite of lichens with a unique dibenzofuran skeleton. Usnic acid inhibits DNA/RNA synthesis and has antibacterial activity. Usnic acid induces cell cycle arrest and apoptosis and has anticancer activity. Usnic acid inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1. Usnic acid has antioxidant and anti-inflammatory activities by inhibiting lipid peroxidation and myeloperoxidase .

HY-N10697

Angulatin G Celangulatin E	Terpenoids Sesquiterpenes Celastraceae Celastrus angulatus Maxim. Plants Source Classification	Parasite
Angulatin G (Celangulatin E) is an insecticidal sesquiterpene polyol ester with a β-dihydroagarofuran sesquiterpene skeleton, which can be isolated from the root bark of Celastrus angulatus. Angulatin G shows LD₅₀ against Mythimna separata of 1656.4 μg/mL .

HY-N3411

Labd-13(E)-ene-8α,15-diol 13E-Labdene-8α,15-diol; Copal-8α,15-diol	Terpenoids Diterpenoids Cistaceae Juss. Plants Source Classification Cistus symphytifolius Lam.	Others
Labd-13(E)-ene-8α,15-diol is a diterpene with the labdane skeleton which can be extracted from Cistus symphytijbfolius .

HY-W013636AR

2-Ketoglutaric acid Sodium (Standard) Alpha-Ketoglutaric acid Sodium (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Tyrosinase Endogenous Metabolite
2-Ketoglutaric acid (Sodium) (Standard) is the analytical standard of 2-Ketoglutaric acid Sodium (HY-W013636A). This product is intended for research and analytical applications. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) Sodium (Standard) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-N11896

10-Hydroxyaloin B	Quinones Structural Classification Anthraquinones Aloe claviflora Burch. Plants Asphodelaceae Source Classification	Others
10-Hydroxyaloin B is a bioactive oxanthrone based on the aloin skeleton .

HY-N14937

Albaflavenone	Structural Classification Microorganisms Antibiotics Terpenoids Sesquiterpenes Source Classification	Antibiotic Bacterial Fungal
Albaflavenone is a sesquiterpene antibiotic with a zizaene skeleton. Albaflavenone is active against Bacillus subtilis .

HY-N13874

Andrastin B	Triterpenes Microorganisms Terpenoids Source Classification	Farnesyl Transferase
Andrastin C is a protein farnesyltransferase inhibitor. Andrastin C has a common androstane skeleton .

HY-N1303

Shoreic acid Shoric acid	Ketones, Aldehydes, Acids Cabralea eichleriana DC. Plants Meliaceae Source Classification	Others
Shoreic acid (compound 8a) is a dammarane skeleton compound isolated from Cabralea eichleriana DC .

HY-N13876

Andrastin D	Triterpenes Microorganisms Terpenoids Source Classification	Farnesyl Transferase
Andrastin D is a protein farnesyltransferase inhibitor. Andrastin D has a common androstane skeleton .

HY-126613

Laurycolactone A	Natural Products Simaroubaceae Plants	Others
Laurycolactone A is a quassinoid with a C18 basic skeleton. Laurycolactone A can be isolated from Eurycoma longifolia .

HY-N11663

Dugesin C	Gynoxys verrucosa Sch.Bip. ex Wedd. Terpenoids Labiatae Diterpenoids Plants Source Classification	Others
Dugesin C is a diterpenoid isolated from the plant Salvia dugesii with a spiro carbocyclic ring system derived from the normal neocrotane skeleton .

HY-N12478

Ainsliadimer A	Caesalpinia crista L. Terpenoids Sesquiterpenes Plants Compositae Source Classification	NO Synthase
Ainsliadimer A is a sesquiterpene lactone dimer with an unusual carbon skeleton. Ainsliadimer A can be obtained from from Ainsliaea macrocephala. Ainsliadimer A inhibits the production of nitric oxide in cells stimulated by LPS .

HY-N6849

InteriotherinA	Classification of Application Fields Lignans Metabolic Disease Phenylpropanoids Plants Schisandraceae Schisandra chinensis (Turcz.) Baill. Disease Research Fields Source Classification	HIV
Interiotherin A is a lignan with a dibenzocyclooctadiene skeleton isolated from Kadsura interior. Interiotherin A inhibits HIV replication to exhibit anti-HIV activity, it has a role as a metabolite and an anti-HIV agent .

HY-W007771R

Acridone (Standard)	Structural Classification Natural Products other families Plants Source Classification	Reference Standards Bacterial BCRP
Acridone (Standard) is the analytical standard of Acridone. This product is intended for research and analytical applications. Acridone is an organic compound based on the acridine skeleton. Acridone has antibacterial, antimalarial, antiviral and anti neoplastic activities .

HY-N9345

(2α,3β)-Olean-12-ene-2,3-diol	Triterpenes other families Classification of Application Fields Terpenoids Other Diseases Plants Disease Research Fields Source Classification	Others
(2α,3β)-Olean-12-ene-2,3-diol (Compound 3) is a triterpenoid with lupane, oleanane, and ursane skeleton .

HY-N6894

Pseudocoptisine acetate Isocoptisine acetate	Alkaloids Phellodendron amurense Rupr. Classification of Application Fields Rutaceae Plants Isoquinoline Alkaloids Disease Research Fields Inflammation/Immunology Source Classification	Cholinesterase (ChE)
Pseudocoptisine (Isocoptisine) acetate is a quaternary alkaloid with benzylisoquinoline skeleton, was isolated from Corydalis Tuber. Pseudocoptisine acetate inhibits acetylcholinesterase (AChE) activity with an IC₅₀ of 12.8 μM. Anti-inflammatory and anti-amnestic effects .

HY-N11977

Stenophyllol B	Phenols Polyphenols Plants Dipterocarpaceae Source Classification Vatica umbonata (Hook.f.) Burck	Others
Stenophyllol B (compound 4) is a trimeric stilbene with bicyclic and bridged tricyclic skeletons. Stenophyllol B was first discovered in the dipterocarps plant and has been found in many species of Hopea, Neobalanocarpus, Shorea, Stemonoporus and Vateri .

HY-N11015

Withaphysalin R	Physalis minima Linn. Plants Solanaceae Steroids Source Classification	Others
Withaphysalin R (compound 5) is a Withanolide that can be isolated from the Solanaceae. Withanolide is a steroid ester with an ergosterol skeleton, and some of these compounds have some significant activities, including cytotoxic and immunosuppressive, antitumor, anti-inflammatory, anticonvulsive, and antioxidant .

HY-N2936

Bi-linderone	Natural Products Plants Lauraceae Lindera aggregata (Sims) Kosterm. Source Classification	Others
Bi-linderone is isolated as racemate from the traditional Chinese medicinal plant Lindera aggregata. Bi-linderone has activity against glucosamine-induced insulin resistance in HepG2 cells at a concentration of 1 μg/mL .

HY-N11646

Ganorbiformin B	Triterpenes Microorganisms Terpenoids Source Classification	Bacterial
Ganorbiformin B is a lanostane triterpenoid. Ganorbiformin B shares the same lanostane skeleton with known ganoderic acids. The C-3 epimer of ganoderic acid T exhibits potent antimycobacterial activity against Mycobacterium tuberculosis H37Ra .

HY-N0829R

Shionone (Standard)	Structural Classification Terpenoids Diterpenoids Plants Compositae Sesbania vesicaria (Jacq.) Elliott	Reference Standards Others
Shionone (Standard) is the analytical standard of Shionone. This product is intended for research and analytical applications. Shionone is the major triterpenoid isolated from Aster tataricus, has anti-tussive, anti-inflammatory activities . Shionone possesses a unique six-membered tetracyclic skeleton and 3-oxo-4-monomethyl structure .

HY-N19310

Stemmadenine	Apocynaceae Structural Classification Alkaloids Tabernaemontana litoralis Kunth Plants Indole Alkaloids Source Classification	Drug Intermediate
Stemmadenine is a strychnos-type monoterpenoid indole alkaloid that serves as a biosynthetic precursor of the monoterpenoid indole alkaloid skeleton .

HY-W013636BR

Calcium 2-oxoglutarate (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Tyrosinase Reference Standards Endogenous Metabolite
Calcium 2-oxoglutarate (Standard) is the analytical standard of Calcium 2-oxoglutarate (HY-W013636B). This product is intended for research and analytical applications. Calcium 2-oxoglutarate is an intermediate in the production of ATP or GTP in the Krebs cycle. Calcium 2-oxoglutarate also acts as the major carbon skeleton for nitrogen-assimilatory reactions. Calcium 2-oxoglutarate is a reversible inhibitor of tyrosinase (IC50=15 mM) .

HY-N17885

16a,17-Dihydroxy lepenine	Structural Classification Alkaloids Other Alkaloids Ranunculaceae Aconitum carmichaeli Debx. Plants Source Classification	Others
16a,17-Dihydroxy lepenine (compound 1) is a C₂₀ diterpenoid alkaloid with an atisine-denudatine skeleton. 16a,17-Dihydroxy lepenine can be isolated from the lateral roots of Aconitum carmichaelii .

HY-N17448

Fraxinuacidoside	Structural Classification Fraxinus sieboldiana Blume Oleaceae Plants Saccharides Monosaccharides Source Classification	Drug Derivative
Fraxinuacidoside functions as a norditerpene glucopyranoside with a unique carbon skeleton. Fraxinuacidoside can be found in the stem bark of Fraxinus sieboldiana .

HY-N17570

23α-Hydroxy-olean-12-en-3-one	Triterpenes Structural Classification Caprifoliaceae Terpenoids Dipsacus asper Wall. Plants Source Classification	Drug Derivative
23α-Hydroxy-olean-12-en-3-one (Compound 15) is a pentacyclic triterpenoid, which is a natural derivative of the oleanane skeleton .

Cat. No.	Product Name	Chemical Structure

HY-W013636S

2-Ketoglutaric acid-13C5

2-Ketoglutaric acid- ¹³C₅ (Alpha-Ketoglutaric acid- ¹³C₅) is a ¹³C labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013636S1

2-Ketoglutaric acid-d4

2-Ketoglutaric acid-d₄ (Alpha-Ketoglutaric acid-d₄) is the deuterium labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid Sodium is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013636S3

2-Ketoglutaric acid-13C

2-Ketoglutaric acid- ¹³C (Alpha-Ketoglutaric acid- ¹³C) is a ¹³C labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013636S2

2-Ketoglutaric acid-d6
2-Ketoglutaric acid-d₆ (Alpha-Ketoglutaric acid-d₆) is the deuterium labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013636S4

2-Ketoglutaric acid-13C2

2-Ketoglutaric acid- ¹³C₂ (Alpha-Ketoglutaric acid- ¹³C₂) is a ¹³C labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-133970S

5α-Cholestane-d6
5α-Cholestane-d₆ is the deuterium labeled 5α-Cholestane (HY-133970). 5α-Cholestane is a skeleton. 5α-Cholestane can be used in the synthesis of Brassinosteroids. 5α-Cholestane can be used in skeletal muscle research .

HY-133970S1

5α-Cholestane-d2
5α-Cholestane-d₂ is the deuterium labeled 5α-Cholestane (HY-133970). 5α-Cholestane is a skeleton. 5α-Cholestane can be used in the synthesis of Brassinosteroids. 5α-Cholestane can be used in skeletal muscle research .

HY-W013973S

p-Terphenyl-d14
p-Terphenyl-d₁₄ is the deuterium labeled p-Terphenyl (HY-W013973). p-Terphenyl is a skeleton. p-Terphenyl derivatives have anticancer activity against liver cancer and pancreatic cancer. p-Terphenyl derivatives also have anti-inflammatory effects .

Cat. No.	Product Name		Classification

HY-153734

Inactive ASO (in vivo) sodium		Antisense Oligonucleotides
Inactive ASO (in vivo) sodium is an inactive Antisense Oligonucleotide. ASO is a class of oligonucleotide molecules, usually composed of 20-30 bases, used to interfere with or regulate gene expression. Inactive ASO (in vivo) sodium is not targeted in the rodent genome and can be used as a negative control for Tofersen. Inactive ASO (in vivo) sodium contains thiophosphate skeleton modification and MOE modification. Cytosine in Inactive ASO (in vivo) is 5' methylcytosine. See References for the location of chemical modifications

HY-138913

2H-Cho-Arg TFA		Cholesterol
2H-Cho-Arg (TFA) is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection.

HY-138912

Cho-Arg TFA		Cholesterol
Cho-Arg TFA is a steroid-based cationic lipid with an L-Arginine headgroup. Cho-Arg TFA shows a remarkably high optimized plasmid DNA transfection efficacy .

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W013636AG

2-Ketoglutaric acid Sodium Alpha-Ketoglutaric acid Sodium	Tyrosinase Endogenous Metabolite	Neurological Disease Metabolic Disease
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) Sodium (GMP) is 2-Ketoglutaric acid Sodium (HY-W013636A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. 2-Ketoglutaric acid Sodium is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

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