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Cat. No.: HY-186210

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TACC3-IN-5

TACC3-IN-5 (Compound 35) is a TACC3 inhibitor. TACC3 is a scaffold protein that is highly expressed in various tumors and regulates microtubule/centrosome stability via phosphorylation by Aurora A. TACC3-IN-5 inhibits the proliferation of triple-negative breast cancer cells. TACC3-IN-5 is applicable for triple-negative breast cancer research.

For research use only. We do not sell to patients.

CAS No.: 3115244-37-3
Formula: C₂₄H₂₅N₅O₂
Molecular Weight:415.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

TACC3-IN-5 Chemical Structure

CAS No.: 3115244-37-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Aurora Kinase Isoforms :

Chemical Information

CAS No. 3115244-37-3
Molecular Weight 415.49
Formula C₂₄H₂₅N₅O₂
SMILES

CN(C)C1=NOC2=CC=C(C3=CC(NC4=CC=CC(N5CCOCC5)=C4)=NC=C3)C=C21
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Yang, et al. Tacc inhibitor compound, pharmaceutical composition, and preparation method therefor and use thereof. WO2026026956.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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TACC3-IN-5

All Aurora Kinase Isoforms