1. Immunology/Inflammation
    Apoptosis
  2. COX
    Apoptosis
  3. Taraxerol acetate

Taraxerol acetate 

Cat. No.: HY-N2599
Handling Instructions

Taraxerol acetate is a COX-1 and COX-2 inhibitor with IC50 values of 116.3 μM and 94.7 μM, respectively. Taraxerol acetate the has the anticancer potential and induces cell apoptosis.

For research use only. We do not sell to patients.

Taraxerol acetate Chemical Structure

Taraxerol acetate Chemical Structure

CAS No. : 2189-80-2

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Description

Taraxerol acetate is a COX-1 and COX-2 inhibitor with IC50 values of 116.3 μM and 94.7 μM, respectively. Taraxerol acetate the has the anticancer potential and induces cell apoptosis[1].

IC50 & Target

COX-1

116.3 μM (IC50)

COX-2

94.7 μM (IC50)

In Vitro

Taraxerol acetate(10-150 µM; 24 or 48 hours) induces a dose- and time-dependent cytotoxic effects in the U87 cells, exhibits IC50 values of 34.2 and 28.4 µM, at 24 and 48 h, respectively[2].
Taraxerol acetate(10, 50 and 150 µM; 24 hours) induces cell apoptosis, the percentage of apoptotic cells increased from 7.3% in the control cells, to 16.1, 44.1 and in the 10, 50 and 150 µM taraxerol acetate-treated cells, respectively. Furthermore, taraxerol acetate treatment led to sub-G1 cell cycle arrest with a corresponding decrease in the number of S-phase cells[2].

Molecular Weight

468.75

Formula

C₃₂H₅₂O₂

CAS No.

2189-80-2

SMILES

C[[email protected]]12C3=CC[[email protected]@](C)(CCC(C)(C)C4)[[email protected]]4([H])[[email protected]@]3(CC[[email protected]]1([H])[[email protected]@]5([[email protected]@](C(C)([[email protected]@H](OC(C)=O)CC5)C)([H])CC2)C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

TaraxerolCOXApoptosisCyclooxygenaseapoptosiscancerglioblastomacellInhibitorinhibitorinhibit

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Taraxerol acetate
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