1. Cell Cycle/DNA Damage Apoptosis
  2. DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Apoptosis
  3. Tezacitabine hydrate

Tezacitabine hydrate is a cytostatic and cytotoxic antimetabolite and nucleoside analogue. Tezacitabine hydrate irreversibly inhibits the ribonucleotide reductase and interferes with DNA replication and repair. Tezacitabine hydrate effectively induces cells Apoptosis. Tezacitabine hydrate has the potential for leukemias and solid tumors (carcinomas) treatment.

For research use only. We do not sell to patients.

Tezacitabine hydrate

Tezacitabine hydrate Chemical Structure

CAS No. : 171176-43-5

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Description

Tezacitabine hydrate is a cytostatic and cytotoxic antimetabolite and nucleoside analogue. Tezacitabine hydrate irreversibly inhibits the ribonucleotide reductase and interferes with DNA replication and repair. Tezacitabine hydrate effectively induces cells Apoptosis. Tezacitabine hydrate has the potential for leukemias and solid tumors (carcinomas) treatment[1][2].

IC50 & Target

Ribonucleotide reductase[1]

Molecular Weight

275.23

Formula

C10H14FN3O5

CAS No.
SMILES

O[C@H]([C@@H](CO)O[C@H]/1N2C(N=C(C=C2)N)=O)C1=C/F.O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Tezacitabine hydrate
Cat. No.:
HY-106015
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