Toborinone
Toborinone is an inotropic agent. Toborinone increases cAMP and intracellular calcium levels through inhibiting PDE. Toborinone inhibits thrombin-induced platelet aggregation with an IC50 of 9.7 μM.
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- CAS 番号: 143343-83-3
- 分子式: C21H24N2O5
- 分子量:384.43
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
化学情報
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CAS 番号 143343-83-3
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分子量 384.43
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分子式 C21H24N2O5
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SMILES
COC1=C(C=CC(CNCC(COC2=CC=C3C(C=CC(N3)=O)=C2)O)=C1)OC
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. MacGowan G. A. (2000). Clinical overview of the novel inotropic agent toborinone. Expert opinion on investigational drugs, 9(5), 1109-1117. [Content Brief]
[2]. Kageyama, K., et al., (2004). Toborinone and olprinone, phosphodiesterase III inhibitors, inhibit human platelet aggregation due to the inhibition of both calcium release from intracellular stores and calcium entry. Journal of anesthesia, 18(2), 107-112. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Toborinone 関連分類
HY-165436 関連分類
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