TOP1362
TOP1362 is a narrow spectrum kinase inhibitor. TOP1362 is a potent inhibitor of P38-α and Syk kinases with Kd values of 26 and 18 nM, respectively and an IC50 of 14 nM in the Src kinase activity assay. TOP1362 potently inhibits P38-α, Src and Syk. TOP1362 can be used in the research of dry eye syndrome.
For research use only. We do not sell to patients.
- CAS No.: 1630203-25-6
- Formula: C43H51N7O8S
- Molecular Weight:825.97
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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p38α |
Chemical Information
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CAS No. 1630203-25-6
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Molecular Weight 825.97
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Formula C43H51N7O8S
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SMILES
O=C(NCCCN1CCOCC1)C2=CC(OC)=CC(NC3=NC=CC(OC4=C5C=CC=CC5=C(NC(NC6=CC(C(C)(C)C)=CC(NS(=O)(C)=O)=C6OC)=O)C=C4)=C3)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)