Trabectedin derivative 1 TFA

Cat. No.: HY-172663A Purity: 99.32%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Trabectedin derivative 1 TFA is a selective DNA minor groove binder. Trabectedin derivative 1 TFA inhibits DNA transcription and repair to induce tumor cell apoptosis. Trabectedin derivative 1 TFA is promising for research of solid tumors such as soft tissue sarcoma and ovarian cancer.

For research use only. We do not sell to patients.

Trabectedin derivative 1 TFA Chemical Structure

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

883.89

Formula

C₄₂H₄₄F₃N₅O₁₁S

Appearance

Solid

Color

White to off-white

SMILES

N#C[C@@H]([C@]1([H])CC2=CC(C)=C3OC)N([C@](CO4)([H])C5=C(OCO6)C6=C7C)[C@@]([C@@](N1C)([H])C2=C3O)([H])[C@@](SC[C@](C8=CC(OC)=C9N)(NCCC8=C9)C4=O)([H])C5=C7OC(C)=O.O=C(O)C(F)(F)F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : ≥ 100 mg/mL (113.14 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.1314 mL	5.6568 mL	11.3136 mL
5 mM	0.2263 mL	1.1314 mL	2.2627 mL
10 mM	0.1131 mL	0.5657 mL	1.1314 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.32%

Select Batch:

Data Sheet (276 KB) SDS (252 KB)

COA (260 KB) HNMR (456 KB) RP-HPLC (262 KB) LCMS (100 KB)

Handling Instructions (2659 KB)

References

[1]. Bin Zou, et al. Anti-alpp/alppl2 antibodies, antibody-drug conjugates, and uses thereof. WO2025048716A1. 2025-03-06.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.1314 mL	5.6568 mL	11.3136 mL	28.2841 mL
	5 mM	0.2263 mL	1.1314 mL	2.2627 mL	5.6568 mL
	10 mM	0.1131 mL	0.5657 mL	1.1314 mL	2.8284 mL
	15 mM	0.0754 mL	0.3771 mL	0.7542 mL	1.8856 mL
	20 mM	0.0566 mL	0.2828 mL	0.5657 mL	1.4142 mL
	25 mM	0.0453 mL	0.2263 mL	0.4525 mL	1.1314 mL
	30 mM	0.0377 mL	0.1886 mL	0.3771 mL	0.9428 mL
	40 mM	0.0283 mL	0.1414 mL	0.2828 mL	0.7071 mL
	50 mM	0.0226 mL	0.1131 mL	0.2263 mL	0.5657 mL
	60 mM	0.0189 mL	0.0943 mL	0.1886 mL	0.4714 mL
	80 mM	0.0141 mL	0.0707 mL	0.1414 mL	0.3536 mL
	100 mM	0.0113 mL	0.0566 mL	0.1131 mL	0.2828 mL