Tri-SM6.1
Tri-SM6.1 is a tridentate small-molecule ligand targeting integrin αvβ6. Tri-SM6.1 binds to integrin αvβ6 on epithelial cells to deliver conjugated α-ENaC RNAi agents.
For research use only. We do not sell to patients.
- CAS No.: 2851077-05-7
- Formula: C159H209N25O39
- Molecular Weight:3094.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
αvβ6 |
Chemical Information
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CAS No. 2851077-05-7
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Molecular Weight 3094.50
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Formula C159H209N25O39
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SMILES
O=C(NCCOCCOCC1=CN(CCOCCOCCOCCOCCOC2=CC=C(C3=CC=C(C=C3)[C@H](CC(O)=O)NC(CNC(CCCNC4=CC(C)=CC=N4)=O)=O)C5=C2C=CC=C5)N=N1)CCC(CCC(NCCOCCOCC6=CN(CCOCCOCCOCCOCCOC7=CC=C(C8=CC=C(C=C8)[C@H](CC(O)=O)NC(CNC(CCCNC9=CC(C)=CC=N9)=O)=O)C%10=C7C=CC=C%10)N=N6)=O)(CCC(NCCOCCOCC(N=N%11)=CN%11CCOCCOCCOCCOCCOC%12=CC=C(C%13=C%12C=CC=C%13)C%14=CC=C([C@@H](NC(CNC(CCCNC%15=CC(C)=CC=N%15)=O)=O)CC(O)=O)C=C%14)=O)NC(CCCC(O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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RNA interference technology
RNA interference (RNAi) is a cellular mechanism that inhibits gene expression by suppressing gene transcription or activating RNA degradation. This mechanism was discovered in plants in 1998 by Andrew Fire and Craig Mello. Today, this phenomenon can be observed in almost all eukaryotes, including protozoa, flies, nematodes, insects, parasites, and mammals.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tri-SM6.1 Related Classifications
HY-185424 Related Classifications
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