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Referencia número: HY-10082B

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Triapine hydrochloride

Name: Triapine hydrochloride
Brand: MedChemExpress
SKU: HY-10082B
Availability: PreOrder

(Synonyms: 3-AP hydrochloride; PAN-811 hydrochloride; OCX191 hydrochloride)

12 Cited Publications

Revisión del cliente

Based on 12 publication(s) in Google Scholar

Triapine (hydrochloride) is the hydrochloride form of Triapine (HY-10082). Triapine (3-AP; PAN-811) is a potent inhibitor of the M2 subunit of ribonucleotide reductase (RR), and is a potent radiosensitizer.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 216240-62-9
Fòrmula: C₇H₁₀ClN₅S
Peso molecular:231.71

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Triapine hydrochloride Chemical Structure

No. CAS: 216240-62-9

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Chemical Information

No. CAS 216240-62-9
Peso molecular 231.71
Fòrmula C₇H₁₀ClN₅S
SMILES

S=C(N)N/N=C/C1=NC=CC=C1N.[H]Cl
Synonyms

3-AP hydrochloride; PAN-811 hydrochloride; OCX191 hydrochloride
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (12)

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Nature

Lithocholic acid phenocopies anti-ageing effects of calorie restriction. [Abstract]

2025 Jul;643(8070):192-200. PMID: 39695227
Cell Death Dis

RRM1 inhibition sensitizes lung adenocarcinoma to decitabine treatment. [Abstract]

2026 Feb 26;17(1):275. PMID: 41748545
Cancer Lett

Inhibition of Ribonucleotide Reductase Subunit M2 Enhances the Radiosensitivity of Metastatic Pancreatic Neuroendocrine Tumor. [Abstract]

2024 Aug 1:596:216993. PMID: 38801884
JACS Au

DefNEtTrp: An Iron Dual Chelator Approach for Anticancer Application. [Abstract]

2024 Dec 4;4(12):4799-4808. PMID: 39735911
mBio

Blockade of de novo dNTP biosynthesis pathway delays HIV-1 early life cycle kinetics and dynamics. [Abstract]

2025 Aug 13;16(8):e0104725. PMID: 40586616
J Mol Med (Berl)

Combination of PARP inhibitor and temozolomide to suppress chordoma progression. [Abstract]

2019 Aug;97(8):1183-1193. PMID: 31201471
J Cancer Res Clin Oncol

Synergistic anticancer activity of combined ATR and ribonucleotide reductase inhibition in Ewing's sarcoma cells. [Abstract]

2023 Sep;149(11):8605-8617. PMID: 37097390
bioRxiv

2026 Jul 22:2026.07.21.736123. PMID: 42539318
Res Sq

2026 Jun 17.
Rush University

2025.
Res Sq

2025 Mar 26.
Research Square Preprint

2023 Jun 9.

Pureza y Documentación

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Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Martin LK, et al. A dose escalation and pharmacodynamic study of Triapine and radiation in patients with locally advanced pancreas cancer. Int J Radiat Oncol Biol Phys. 2012 Nov 15;84(4):e475-81. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Triapine hydrochloride

12 Cited Publications

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Publications (12)
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Triapine hydrochloride

Publications Citing Use of MedChemExpress (MCE) Triapine hydrochloride

Ver todos los productos específicos de isoformas DNA/RNA Synthesis

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Publications (12)

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Triapine hydrochloride

Publications Citing Use of MedChemExpress (MCE) Triapine hydrochloride

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Publications (12)

Pureza y Documentación

Referencias

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