G-479
G-479 is the inhibitor for MEK and hERG channel (IC50=14 μM). G-479 inhibits the proliferation of HCT-116 and A375 with IC50 of 0.049 μM and 0.004 μM. G-479 exhibits good metabolic stability in liver microsomes and good pharmacokinetic characteristics in rats.
For research use only. We do not sell to patients.
- CAS No.: 1168092-22-5
- Formula: C16H15FIN5O4
- Molecular Weight:487.22
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All MEK Isoforms
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Biological Activity
Chemical Information
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CAS No. 1168092-22-5
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Molecular Weight 487.22
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Formula C16H15FIN5O4
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SMILES
O=C(C1=C(NC2=CC=C(I)C=C2F)N3C(C=N1)=CN=C3)NOC[C@H](O)CO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)