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Brivekimig

(Synonyms: F-027300252; SAR-442970)
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Based on 1 Customer Validation

Brivekimig (F-027300252; SAR-442970) is a bispecific nanobody targeting TNF/OX40L. Brivekimig is applicable to research related to hidradenitis suppurativa.

For research use only. We do not sell to patients.

  • Purity: 98%
  • CAS No.: 2834733-45-6
  • Molecular Weight:66.21 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Brivekimig
  • Experimental Validation Results for Brivekimig
  • Experimental Validation Results for Brivekimig
  • Experimental Validation Results for Brivekimig
  • Brivekimig Chemical Structure
    Brivekimig Chemical Structure
CAS No.: 2834733-45-6
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Brivekimig Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Use of MCE Products

All TNF Receptor Isoforms

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Assay Types
  • 1/16

    5VH

  • 1/16

    Loaded Brivekimig on AHC2 biosensor, can bind Serum Albumin/ALB Protein, Human (HEK293, His-Avi, HY-P78393) with an affinity constant of 3.668E-09 M as determined in BLI assay.

  • 1/16

    Loaded Brivekimig on AHC2 biosensor, can bind TNF alpha protein, Human (His, HY-P70426A) with an affinity constant of <1.0E-12 M as determined in BLI assay.

  • 1/16

    Flow cytometric analysis of 1X106 HUVEC cells with Brivekimig (HY-P990907, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Brivekimig Chemical Structure
    1/16
  • Brivekimig
  • Loaded Brivekimig on AHC2 biosensor, can bind Serum Albumin/ALB Protein, Human (HEK293, His-Avi, HY-P78393) with an affinity constant of 3.668E-09 M as determined in BLI assay.
  • Loaded Brivekimig on AHC2 biosensor, can bind TNF alpha protein, Human (His, HY-P70426A) with an affinity constant of <1.0E-12 M as determined in BLI assay.
  • Flow cytometric analysis of 1X106 HUVEC cells with Brivekimig (HY-P990907, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • 5VH