VEGFR-2-IN-36
VEGFR-2-IN-36 (compound 15) is a VEGFR-2 inhibitor (IC50: 0.067 μM) and inducer of apoptosis with anticancer activity. VEGFR-2-IN-36 upregulates BAX levels and downregulates Bcl-2 levels. VEGFR-2-IN-36 is toxic to cancer cells, MCF-7 (IC50=0.42 μM) and HepG2 (IC50=0.22 μM).
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- Fòrmula: C24H23N7O5
- Peso molecular:489.48
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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- Pureza y Documentación
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Help & FAQs
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Actividad biológica
Descripciòn
IC50 & Target
IC50: 0.067 μM (VEGFR-2)[1]
Chemical Information
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Peso molecular 489.48
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Fòrmula C24H23N7O5
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SMILES
CN(C=N1)C2=C1N(C)C(N(CC(NC3=CC=C(/C(C)=N/NC(C4=CC=C(O)C=C4)=O)C=C3)=O)C2=O)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
VEGFR-2-IN-36 Related Classifications
HY-155242 Related Classifications
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