WRN-IN-22
WRN-IN-22 (compound A01) is a potent Werner syndrome RecQ helicase (WRN) inhibitor (IC50 < 100 nM). WRN-IN-22 can be used for microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) cancer research, such as colorectal, gastric, prostate and endometrial cancer.
For research use only. We do not sell to patients.
- Formula: C32H27ClF3N7O6
- Molecular Weight:698.05
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
More
Biological Activity
|
Helicase |
Chemical Information
-
Molecular Weight 698.05
-
Formula C32H27ClF3N7O6
-
SMILES
O=C1C2=C(C3OC24CCN(C(C5=C(O)C=CC=N5)=O)CC4)N(C(C(NC6=CC=C(C(F)(F)F)C=C6Cl)=O)C3)C7=NC(C8=CCOCC8)=NN71
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)