Z52-L16
Z52-L16 is Drug-Linker Conjugates for ADC, which is composed of a linker and a Ras inhibitor Z52 (HY-178842). Z52-L16 can be used for the research of cancer, such as pancreatic cancer.
For research use only. We do not sell to patients.
- CAS No.: 3077488-80-0
- Formula: C130H196N14O45S
- Molecular Weight:2707.08
-
Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
All Drug-Linker Conjugates for ADC Isoforms
More
Biological Activity
Chemical Information
-
CAS No. 3077488-80-0
-
Appearance Solid
-
Molecular Weight 2707.08
-
Formula C130H196N14O45S
-
Color White to off-white
-
SMILES
N#CC1(CNC(OCC2=CC=C(O[C@@H]3O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]3O)C(NC(CCNC([C@@H](NC(CCN4C(C=CC4=O)=O)=O)CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)=O)=C2)=O)CCN(CC1)CC#CC5=C[C@@]([C@@]6=C7C8=CC(C9=CSC(C[C@H](NC([C@@H]%10[C@H]%11COC[C@@H]%10%11)=O)C(N%12N[C@H](C(OCC(C7)(C)C)=O)CCC%12)=O)=N9)=CC=C8N6CC)=C(N=C5)[C@@H](OC)C
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (36.94 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (276 KB)
-
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.3694 mL | 1.8470 mL | 3.6940 mL | 9.2350 mL |
| 5 mM | 0.0739 mL | 0.3694 mL | 0.7388 mL | 1.8470 mL | |
| 10 mM | 0.0369 mL | 0.1847 mL | 0.3694 mL | 0.9235 mL | |
| 15 mM | 0.0246 mL | 0.1231 mL | 0.2463 mL | 0.6157 mL | |
| 20 mM | 0.0185 mL | 0.0924 mL | 0.1847 mL | 0.4618 mL | |
| 25 mM | 0.0148 mL | 0.0739 mL | 0.1478 mL | 0.3694 mL | |
| 30 mM | 0.0123 mL | 0.0616 mL | 0.1231 mL | 0.3078 mL |