1. Signaling Pathways
  2. GPCR/G Protein
  3. Ras
  4. Ras Isoform
  5. Ras Inhibitor

Ras Inhibitor

Ras Inhibitors (127):

Cat. No. Product Name Effect Purity
  • HY-15723A
    NSC 23766 trihydrochloride
    Inhibitor 99.32%
    NSC 23766 trihydrochloride is an inhibitor of Rac1 activation.
  • HY-12755
    Inhibitor 99.71%
    ML141 (CID-2950007) is a potent, allosteric, selective and reversible non-competitive inhibitor of Cdc42 GTPase.
  • HY-15136
    Inhibitor 98.67%
    Lonafarnib (Sch66336) is a potent and orally active farnesyl transferase (FTase) inhibitor.
  • HY-13452
    Inhibitor 98.06%
    CID-1067700 (ML282) is a pan GTPase inhibitor, and competitively inhibits Ras-related in brain 7 (Rab7) with a Ki of 13 nM.
  • HY-12646
    Rhosin hydrochloride
    Inhibitor 99.93%
    Rhosin hydrochloride is a potent, specific RhoA subfamily Rho GTPases inhibitor.
  • HY-123673
    Inhibitor 99.82%
    MCP110 is an inhibitor of Ras/Raf-1 interaction.
  • HY-138294
    Inhibitor 98.41%
    RAS/RAS-RAF-IN-1 is a potent RAS and RAS-RAF inhibitor.
  • HY-107753
    Inhibitor 98.42%
    XRP44X inhibits Ras-induced transcription activation with the IC50 of 10 nM.
  • HY-16659
    EHT 1864
    Inhibitor 99.85%
    EHT 1864 is an inhibitor of Rac family small GTPases.
  • HY-15871
    GGTI298 Trifluoroacetate
    Inhibitor 99.87%
    GGTI298 Trifluoroacetate is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, which can inhibit Rap1A with IC50 of 3 μM; little effect on Ha-Ras with IC50 of >20 μM.
  • HY-14754
    Inhibitor 99.01%
    Salirasib is a potent and competitive prenylated protein methyltransferase (PPMTase) inhibitor with Ki of 2.6 μM, which inhibits Ras methylation.
  • HY-15872A
    FTI-277 hydrochloride
    Inhibitor ≥98.0%
    FTI-277 hydrochloride is an inhibitor of farnesyl transferase (FTase); a highly potent Ras CAAX peptidomimetic which antagonizes both H- and K-Ras oncogenic signaling.
  • HY-12874
    Inhibitor 99.82%
    CASIN is a selective GTPase Cdc42 inhibitor with an IC50 of 2 uM.
  • HY-101295
    Inhibitor 99.16%
    Pan-RAS-IN-1 is a pan-Ras inhibitor that disrupts the interaction of Ras proteins and their effectors.
  • HY-13991
    Inhibitor 99.94%
    CCG-1423 is an inhibitor of Rho/MRTF/SRF pathway.
  • HY-12810
    Inhibitor 99.43%
    EHop-016 is a potent and selective Rac GTPase Rac1 and Rac3 inhibitor.
  • HY-100876
    GGTI298 is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, strongly inhibiting the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras, with IC50 values of 3 and > 20 μM in vivo, respectively.
  • HY-U00145
    Digeranyl bisphosphonate
    Inhibitor ≥98.0%
    Digeranyl bisphosphonate (DGBP) is a potent geranylgeranylpyrophosphate (GGPP) synthase inhibitor, which inhibits geranylgeranylation of Rac1.
  • HY-121750
    Inhibitor 99.85%
    CCG-222740 is an orally active and selective Rho/myocardin-related transcription factor (MRTF) pathway inhibitor.
  • HY-111424
    Inhibitor 98.12%
    BDP9066 is a potent and selective myotonic dystrophy-related Cdc42-binding kinase MRCK inhibitor with an IC50 of 64 nM for MRCKβ in SCC12 cells, Ki values of 0.0136 nM and 0.0233 nM for MRCKα/β in house determinations, respectively.