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Cat. No.: HY-170652

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ZQMT-10

ZQMT-10 is an orally active and potent antagonist of TRPA1, with the K_d of 1.04 μM. ZQMT-10 plays an important role in cancer research.

For research use only. We do not sell to patients.

CAS No.: 1791309-86-8
Formula: C₁₆H₁₃FN₂O₂
Molecular Weight:284.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

ZQMT-10 Chemical Structure

CAS No.: 1791309-86-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

ZQMT-10 is an orally active and potent antagonist of TRPA1, with the K_d of 1.04 μM. ZQMT-10 plays an important role in cancer research^[1].

IC₅₀ & Target^[1]

TRPA1

1.04 μM (Ki)

All TRP Channel Isoforms :

Chemical Information

CAS No. 1791309-86-8
Molecular Weight 284.29
Formula C₁₆H₁₃FN₂O₂
SMILES

O=C(C1=CC=C2NC(CC2=C1)=O)NCC3=CC=C(C=C3)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yiming Qi, et al. Discovery of novel oxindole derivatives as TRPA1 antagonists with potent analgesic activity for pain treatment. Bioorg Chem. 2025 Jan:154:108088. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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ZQMT-10

All TRP Channel Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

ZQMT-10 Related Classifications

HY-170652 Related Classifications