11-Deoxy Prostaglandin E2
Based on 1 Customer Validation
11-Deoxy Prostaglandin E2 is a selective agonist of EP4 with an EC50 of 0.66 nM. 11-Deoxy Prostaglandin E2 is an analog of prostaglandin E2. 11-Deoxy Prostaglandin E2 can be used in study bone healing, heart failure, and other receptor associated conditions.
For research use only. We do not sell to patients.
- Purity: 99.0%
- CAS No.: 35536-53-9
- Formula: C20H32O4
- Molecular Weight:336.47
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 35536-53-9
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Appearance Solid
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Molecular Weight 336.47
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Formula C20H32O4
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Color White to off-white
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SMILES
CCCCC[C@@H](/C=C/[C@@H](CCC1=O)[C@H]1C/C=C\CCCC(O)=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (297.20 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (557 KB)
- English - EN (557 KB)
- Français - FR (557 KB)
- Deutsch - DE (557 KB)
- Norwegian - NO (557 KB)
- Español - ES (557 KB)
- Swedish - SV (557 KB)
- Italian - IT (557 KB)
- Korean - KR (557 KB)
- Portuguese - PT (557 KB)
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Handling Instructions (2659 KB)
References
[1]. Holt MC, et al. Improved homology modeling of the human & rat EP4 prostanoid receptors. BMC Mol Cell Biol. 2019 Aug 27;20(1):37. [Content Brief]
[2]. Ungrin MD, et al. Key structural features of prostaglandin E(2) and prostanoid analogs involved in binding and activation of the human EP(1) prostanoid receptor. Mol Pharmacol. 2001 Jun;59(6):1446-56. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9720 mL | 14.8602 mL | 29.7203 mL | 74.3008 mL |
| 5 mM | 0.5944 mL | 2.9720 mL | 5.9441 mL | 14.8602 mL | |
| 10 mM | 0.2972 mL | 1.4860 mL | 2.9720 mL | 7.4301 mL | |
| 15 mM | 0.1981 mL | 0.9907 mL | 1.9814 mL | 4.9534 mL | |
| 20 mM | 0.1486 mL | 0.7430 mL | 1.4860 mL | 3.7150 mL | |
| 25 mM | 0.1189 mL | 0.5944 mL | 1.1888 mL | 2.9720 mL | |
| 30 mM | 0.0991 mL | 0.4953 mL | 0.9907 mL | 2.4767 mL | |
| 40 mM | 0.0743 mL | 0.3715 mL | 0.7430 mL | 1.8575 mL | |
| 50 mM | 0.0594 mL | 0.2972 mL | 0.5944 mL | 1.4860 mL | |
| 60 mM | 0.0495 mL | 0.2477 mL | 0.4953 mL | 1.2383 mL | |
| 80 mM | 0.0372 mL | 0.1858 mL | 0.3715 mL | 0.9288 mL | |
| 100 mM | 0.0297 mL | 0.1486 mL | 0.2972 mL | 0.7430 mL |
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