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Cat. No.: HY-113058R

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3-Hydroxyoctanoic acid (Standard)

3-Hydroxyoctanoic acid (Standard) is the analytical standard of 3-Hydroxyoctanoic acid (HY-113058). This product is intended for research and analytical applications. 3-Hydroxyoctanoic acid is a medium-chain β-hydroxy fatty acid that possesses antibacterial, antifungal, and quorum-sensing regulatory activities. 3-Hydroxyoctanoic acid is an endogenous agonist of the human HCAR3 receptor, decreases intracellular cAMP, reduces IL-1beta secretion, increases IL-10 secretion, and decreases ROS production in macrophages. 3-Hydroxyoctanoic acid inhibits quorum-sensing-regulated pyocyanin production in Pseudomonas aeruginosa PAO1 and inhibits the yeast-to-hypha transition in Candida albicans. 3-Hydroxyoctanoic acid is used in research related to metabolism, bacterial infections, and fungal infections.

For research use only. We do not sell to patients.

CAS No.: 14292-27-4
Formula: C₈H₁₆O₃
Molecular Weight:160.21

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Please store the product under the recommended conditions in the Certificate of Analysis.

3-Hydroxyoctanoic acid (Standard) Chemical Structure

CAS No.: 14292-27-4

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 14292-27-4
Molecular Weight 160.21
Formula C₈H₁₆O₃
SMILES

O=C(CC(CCCCC)O)O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Peters A, et al. Hydroxycarboxylic acid receptor 3 and GPR84 - Two metabolite-sensing G protein-coupled receptors with opposing functions in innate immune cells. Pharmacological research. 2022 Feb;176:106047.

[2]. Kapolka NJ, et al. HCAR3: an underexplored metabolite sensor. Nat Rev Drug Discov. 2020 Oct;19(11):745.

[3]. Radivojevic J, et al. Polyhydroxyalkanoate-based 3-hydroxyoctanoic acid and its derivatives as a platform of bioactive compounds. Applied microbiology and biotechnology. 2016 Jan;100(1):161-72.

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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3-Hydroxyoctanoic acid (Standard)

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