3-Methoxyphenylethylamine
Based on 1 Customer Validation
3-Methoxyphenylethylamine is an organic compound that is used as an intermediate for pharmaceuticals, dyestuffs, and liquid crystal materials.
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- Purity: 99.39%
- CAS No.: 2039-67-0
- 화학식: C9H13NO
- 분자량:151.21
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보관:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO-K1 | EC50 |
1444 nM
Compound: 18
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Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal calcium mobilization by calcium 3 assay
Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal calcium mobilization by calcium 3 assay
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[PMID: 18602830] |
3-Methoxyphenylethylamine is a substrate of cytochrome P450 2D6 (CYP2D6) and can be oxidized by CYP2D6. 3-Methoxyphenylethylamine can be used as a model substrate in drug metabolism studies to study the catalytic mechanism and substrate selectivity of CYP2D6[2].
The oxidation product of 3-Methoxyphenylethylamine can be used as a precursor of norepinephrine and plays a role in the nervous system[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2039-67-0
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Appearance Liquid (Density: 1.008±0.06 g/cm3)
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분자량 151.21
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화학식 C9H13NO
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Color Colorless to light yellow
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SMILES
NCCC1=CC(OC)=CC=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 100 mg/mL (661.33 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (269 KB)
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SDS (476 KB)
- English - EN (476 KB)
- Français - FR (476 KB)
- Deutsch - DE (476 KB)
- Norwegian - NO (476 KB)
- Español - ES (476 KB)
- Swedish - SV (476 KB)
- Italian - IT (476 KB)
- Korean - KR (476 KB)
- Portuguese - PT (476 KB)
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Handling Instructions (2659 KB)
References
[1]. Filippo Erli, et al. Highly Potent and Selective New Diphenethylamines Interacting with the κ-Opioid Receptor: Synthesis, Pharmacology, and Structure-Activity Relationships. J Med Chem. 2017 Sep 14;60(17):7579-7590. [Content Brief]
[2]. Miller GP, et al., Oxidation of phenethylamine derivatives by cytochrome P450 2D6: the issue of substrate protonation in binding and catalysis. Biochemistry. 2001 Nov 27;40(47):14215-23. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.6133 mL | 33.0666 mL | 66.1332 mL | 165.3330 mL |
| 5 mM | 1.3227 mL | 6.6133 mL | 13.2266 mL | 33.0666 mL | |
| 10 mM | 0.6613 mL | 3.3067 mL | 6.6133 mL | 16.5333 mL | |
| 15 mM | 0.4409 mL | 2.2044 mL | 4.4089 mL | 11.0222 mL | |
| 20 mM | 0.3307 mL | 1.6533 mL | 3.3067 mL | 8.2666 mL | |
| 25 mM | 0.2645 mL | 1.3227 mL | 2.6453 mL | 6.6133 mL | |
| 30 mM | 0.2204 mL | 1.1022 mL | 2.2044 mL | 5.5111 mL | |
| 40 mM | 0.1653 mL | 0.8267 mL | 1.6533 mL | 4.1333 mL | |
| 50 mM | 0.1323 mL | 0.6613 mL | 1.3227 mL | 3.3067 mL | |
| 60 mM | 0.1102 mL | 0.5511 mL | 1.1022 mL | 2.7555 mL | |
| 80 mM | 0.0827 mL | 0.4133 mL | 0.8267 mL | 2.0667 mL | |
| 100 mM | 0.0661 mL | 0.3307 mL | 0.6613 mL | 1.6533 mL |
3-Methoxyphenylethylamine Related Classifications
HY-41268 Related Classifications
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