7-Deazaguanosine
Based on 1 Customer Validation
7-Deazaguanosine is a purine nucleoside analogue with antitrypanosomal activity.
For research use only. We do not sell to patients.
- Purity: 98.53%
- CAS No.: 62160-23-0
- Formula: C11H14N4O5
- Molecular Weight:282.25
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Storage:
-20°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
All Parasite Isoforms
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Biological Activity
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Trypanosoma |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MRC5 | EC50 |
>64 μM
Compound: 18
|
Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 3 days by resazurin dye based fluorescence assay
Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 3 days by resazurin dye based fluorescence assay
|
[PMID: 31931339] |
Chemical Information
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CAS No. 62160-23-0
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Appearance Solid
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Molecular Weight 282.25
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Formula C11H14N4O5
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Color White to off-white
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SMILES
O[C@H]1[C@@H](O)[C@H](N(C=C2)C3=C2C(NC(N)=N3)=O)O[C@@H]1CO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [Content Brief]
[2]. Hulpia F, Bouton J, Campagnaro GD, et al. C6-O-alkylated 7-deazainosine nucleoside analogues: Discovery of potent and selective anti-sleeping sickness agents. Eur J Med Chem. 2020;188:112018. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)