MB-7133
MB-7133 is a liver-targeted HepDirect prodrug of Cytarabine (HY-13605) monophosphate. Through cytochrome P450-mediated oxidation, MB-7133 selectively releases monophosphorylated Cytarabine in CYP3A4-expressing hepatocytes. MB-7133 inhibits DNA synthesis and kills primary liver cancer cells via the active metabolite Cytarabine triphosphate (ara-CTP) (HY-115740). MB-7133 can be used for research on hepatocellular carcinoma.
For research use only. We do not sell to patients.
- CAS No.: 685111-92-6
- Formula: C17H21N4O8P
- Molecular Weight:440.34
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
All DNA/RNA Synthesis Isoforms
More
Biological Activity
Description
|
DNA |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 685111-92-6
-
Molecular Weight 440.34
-
Formula C17H21N4O8P
-
SMILES
NC(C=CN1[C@H]2[C@H]([C@H](O)[C@@H](CO[P@]3(OCC[C@H](O3)C4=CC=NC=C4)=O)O2)O)=NC1=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MB-7133 Related Classifications
HY-16311 Related Classifications
Powered by Bioz
Keywords