1. Apoptosis
    Metabolic Enzyme/Protease
  2. MDM-2/p53
    E1/E2/E3 Enzyme
  3. MX69


Cat. No.: HY-100892 Purity: 99.65%
Handling Instructions

MX69 is an inhibitor of MDM2/XIAP, used for cancer treatment.

For research use only. We do not sell to patients.

MX69 Chemical Structure

MX69 Chemical Structure

CAS No. : 1005264-47-0

Size Price Stock Quantity
10 mM * 1  mL in DMSO USD 150 In-stock
Estimated Time of Arrival: December 31
1 mg USD 84 In-stock
Estimated Time of Arrival: December 31
5 mg USD 144 In-stock
Estimated Time of Arrival: December 31
10 mg USD 228 In-stock
Estimated Time of Arrival: December 31
50 mg USD 912 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1560 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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MX69 is an inhibitor of MDM2/XIAP, used for cancer treatment.

In Vitro

MX69 blocks the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation. MX69 shows minimal inhibitory effect on normal human hematopoiesis in vitro and is very well tolerated in animal models. MX69-induced MDM2 downregulation results not only in inhibition of XIAP expression, but also in activation of p53, which contributes to cancer cell apoptosis in vitro[1].

In Vivo

MX69-induced MDM2 downregulation results in activation of p53 which contributes to inhibition of cancer cell proliferation in vivo[1].

Molecular Weight









Room temperature in continental US; may vary elsewhere.

Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 30 mg/mL (63.22 mM)

*"≥" means soluble, but saturation unknown.

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1072 mL 10.5359 mL 21.0717 mL
5 mM 0.4214 mL 2.1072 mL 4.2143 mL
10 mM 0.2107 mL 1.0536 mL 2.1072 mL
*Please refer to the solubility information to select the appropriate solvent.

Purity: 99.65%

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MX69MX 69MX-69MDM-2/p53IAPE1/E2/E3 EnzymeE1 activating enzymeE2 conjugating enzymeE3 ligating enzymeUbiquitin activating enzymeUbiquitin conjugating enzymeUbiquitin ligaseInhibitorinhibitorinhibit

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