2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P992440
    PF-06817024 98%
    PF-06817024 is a high affinity, humanized antibody that binds IL-33. PF-06817024 binds to IL-33, prevents IL-33 from binding to receptor ST2, and inhibits downstream type 2 inflammatory responses. PF-06817024 can be used for the research of allergic diseases.
    PF-06817024
  • HY-P992447
    QX008N 98%
    QX008N is a humanized IgG1 monoclonal antibody and also a TSLP inhibitor with a KD value of 0.0175 nM. QX008N blocks TSLP-induced signaling pathways by inhibiting the interaction of TSLP-TSLPR-IL-7Rα. QX008N reduces eosinophil and IgE levels, improves pulmonary function, blocks TSLP-induced inflammation, and enhances the inhibitory effect on inflammatory mediators when administered in combination with anti-IL-4R antibodies. QX008N is applicable to relevant research on asthma.
    QX008N
  • HY-P992453
    RO-7303509 98%
    RO-7303509 (MTBT1466A; RG-6315) is a human monoclonal antibody and TGFβ3 neutralizer. RO-7303509 targets the profibrotic mediator TGFβ3 to alleviate fibrosis. RO-7303509 can be administered via subcutaneous or intravenous routes and is used in research on systemic sclerosis. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001).
    RO-7303509
  • HY-P992473
    TAS266 98%
    TAS266 is a tetrameric nanobody agonist targeting DR5. TAS266 selectively induces cancer cell death. TAS266 triggers sustained tumor regression in xenograft models and also elicits immunogenic responses including antibody binding. TAS266 exhibits superior anti-tumor efficacy compared with traditional DR5-targeting strategies. TAS266 can be used in research related to pancreatic cancer and advanced solid tumors.
    TAS266
  • HY-P992474
    TAVO101 98%
    TAVO101 is a humanized anti-TSLP antibody with an EC50 of 0.19 nM against hTSLP. TAVO101 inhibits STAT5 activation and CCL17 release. TAVO101 carries Fc region mutations that enhance its binding to FcRn while reducing its binding to FcγRI, FcγRIIIA and C1q, thereby attenuating effector functions. TAVO101 reduces the levels of inflammatory markers, cell infiltration and histopathological damage in preclinical models of asthma, psoriasis and atopic dermatitis. TAVO101 can be used for research related to asthma, psoriasis and atopic dermatitis.
    TAVO101
  • HY-P992480
    VAK-694 98%
    VAK-694 is a fully humanized anti-IL-4 monoclonal antibody. VAK-694 can be used for the research of seasonal allergic rhinitis.
    VAK-694
  • HY-P992486
    XKH001 98%
    XKH001 is a recombinant humanized IgG1 monoclonal antibody targeting IL-25. XKH001 has low immunogenicity. XKH001 can be used for the research of type 2 inflammatory diseases.
    XKH001
  • HY-P992487
    ZL-1211 98%
    ZL-1211 is an anti-CLDN18.2 monoclonal antibody. ZL-1211 exhibits enhanced binding affinity to CD16A. ZL-1211 induces ADCC-mediated cell lysis and triggers the production of IFNγ, TNFα and IL6. ZL-1211 promotes antibody-dependent cellular cytotoxicity. ZL-1211 exerts anti-tumor activity in a mouse xenograft model of gastric cancer. ZL-1211 can be used for the research of gastric cancer.
    ZL-1211
  • HY-P992489
    Mouse IgG1 lambda, Isotype Control 98%
    Mouse IgG1 lambda, Isotype Control is an isotype control for?Mouse IgG1 lambda.
    Mouse IgG1 lambda, Isotype Control
  • HY-P992490
    VHH mouse IgG2a Fc, Isotype Control 98%
    VHH mouse IgG2a Fc, Isotype Control is an isotype control for?VHH mouse IgG2a Fc.
    VHH mouse IgG2a Fc, Isotype Control
  • HY-P992491
    VHH human IgG4 Fc, Isotype Control 98%
    VHH human IgG4 Fc, Isotype Control is an isotype control for?VHH human IgG4 Fc.
    VHH human IgG4 Fc, Isotype Control
  • HY-P992492
    VHH human IgG1 Fc, Isotype Control 98%
    VHH human IgG1 Fc, Isotype Control is an isotype control for?VHH human IgG1 Fc.
    VHH human IgG1 Fc, Isotype Control
  • HY-P992493
    Fab-His (Human IgG1), Isotype Control 98%
    Fab-His (Human IgG1), Isotype Control is an isotype control for?Fab-His (Human IgG1).
    Fab-His (Human IgG1), Isotype Control
  • HY-P992494
    scFv human IgG1 Fc, Isotype Control 98%
    scFv human IgG1 Fc, Isotype Control is an isotype control for?scFv human IgG1 Fc.
    scFv human IgG1 Fc, Isotype Control
  • HY-P992495
    Human IgD kappa, Isotype Control 98%
    Human IgD kappa, Isotype Control is an isotype control for?Human IgD kappa.
    Human IgD kappa, Isotype Control
  • HY-P992496
    Human IgG3 lambda, Isotype Control 98%
    Human IgG3 lambda, Isotype Control is an isotype control for?Human IgG3 lambda.
    Human IgG3 lambda, Isotype Control
  • HY-P992497
    Rat IgM, Isotype Control 98%
    Rat IgM, Isotype Control is an isotype control for?Rat IgM.
    Rat IgM, Isotype Control
  • HY-P992498
    Human IgM, Isotype Control 98%
    Human IgM, Isotype Control is an isotype control for?Human IgM.
    Human IgM, Isotype Control
  • HY-P992499
    Rat IgE, Isotype Control 98%
    Rat IgE, Isotype Control is an isotype control for?Rat IgE.
    Rat IgE, Isotype Control
  • HY-P992500
    Rat IgG2b lambda, Isotype Control 98%
    Rat IgG2b lambda, Isotype Control is an isotype control for?Rat IgG2b lambda.
    Rat IgG2b lambda, Isotype Control
Cat. No. Product Name / Synonyms Application Reactivity