Metabolic Disease

Midaglizole (Standard) is the analytical standard of Midaglizole. This product is intended for research and analytical applications. Midaglizole ((±)-DG5128 free base; DG5128 free base) is a potent α2-adrenoceptor antagonist. Midaglizole is a hypoglycemic agent. Midaglizole increases blood pressure and reduces blood glucose levels in vivo.

3-Bromopyruvic acid (Standard) is the analytical standard of 3-Bromopyruvic acid (HY-19992). This product is intended for research and analytical applications. 3-Bromopyruvate (Bromopyruvic acid) is an analogue of pyruvate and a potent hexoK_inase (HK)-II inhibitor with high tumor selectivity. 3-Bromopyruvate inhibits cell growth and induces apoptosis through interfering with glycolysis. 3-Bromopyruvate induces autophagy by stimulating ROS formation in breast cancer cells. Antimicrobial activities.

1,2-Linolenin-3-myristin is an acylglycerol.

Methyl 10-methylheptadecanoate is an ester product.

1,2,3-Tri-13(E)-docosenoyl glycerol (Tribrassidin; TG(22:1/22:1/22:1)) is an orally consumable triglyceride. 1,2,3-Tri-13(E)-docosenoyl glycerol was added to the diet of rats by mixing it with corn oil and undergoing ester exchange to improve its digestion and absorption.

Methyl 7(R)-hydroxyhexadecanoate is an ester product.

Latanoprost lactone diol (Standard) is the analytical standard of Latanoprost lactone diol (HY-125946). This product is intended for research and analytical applications. Latanoprost lactone diol is a small organic molecule derived from Prostaglandin F2α (HY-12956), and is a key synthetic intermediate and inactive metabolically related form of Latanoprost (HY-B0577). Latanoprost lactone diol is significantly upregulated in hypothyroid rats, and its levels can be reversed by the crude polysaccharide, lactone, and oligosaccharide components of the rhizome of Atractylodis macrocephalae. Latanoprost lactone diol can be used for research related to hypothyroidism.

Bisphenol F-¹³C₁₂ is the ¹³C labeled Bisphenol F (HY-W014901). Bisphenol F is an orally active endocrine disruptor. Bisphenol F promotes ROS generation, upregulates p-AKT/p-GSK3β, and induces Apoptosis. Bisphenol F interferes with glucose metabolism, affects neurodevelopment and reproductive function. Bisphenol F reduces social novelty preference in mouse offspring. Bisphenol F can be used in bone, blood, and fat-related studies. Bisphenol F is used as a substitute for Bisphenol A (HY-18260).

2-Hexadecenal, a long-chain fatty aldehyde, is a byproduct of sphingolipid metabolism, involved in cytoskeletal reorganization, DNA damage, and apoptosis. 2-Hexadecenal regulates ROS production and induces apoptosis in polymorphonuclear leucocytes.

Lesinurad-d₄ (RDEA594-d₄) is deuterium labeled Lesinurad. Lesinurad is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with K_m values of 0.85 and 2 μM, respectively.

ω-Muricholic acid-d₄ (ω-MCA-d₄) is deuterium labeled ω-Muricholic Acid. ω-Muricholic acid (ω-MCA) is a murine-specific secondary bile acid.

Lansoprazole N-oxide (Comound 2) is the overoxidized by-product found in the synthesis of the proton pump inhibitor Lansoprazole (HY-13662). Lansoprazole N-oxide is promising for research of duodenal and gastric ulcers, reflux oesophagitis, and Zollinger–Ellison syndrome.

Myristoleyl myristate ((Z)-Tetradec-9-en-1-yl tetradecanoate) is an ester product.

Eicosane (Standard) is the analytical standard of Eicosane. This product is intended for research and analytical applications. Eicosane is an ester product.

1,2-Diheptadecanoyl-rac-glycerol is a diacylglycerol that contains Heptadecanoic acid (HY-W004284) at the sn-1 and sn-2 positions.

DSA8 is a type II kinase inhibitor with IRE1 RNase modulating activity. DSA8 can be used for the research of cancer, metabolic disease, suah as diabetes.

12-Pentacosanone (pentacosan-12-one) is an ester product.

2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one is a natural product found in the leaves and stem bark of M. glabra. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one displays binding affinities with dipeptidyl peptidase-4 (DPP-4) and α-Amylase. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one has potential antidiabetic activities.

Compound amino acids solution (18AA) is a nutritional supplement solution containing 18 essential and non-essential amino acids, which can improve the nutritional status.

Cilobamine methanesulfonate is an orally active antidepressant and a dopamine/norepinephrine reuptake inhibitor. Cilobamine methanesulfonate increases the levels of Aniline hydroxylase and cytochrome P-450 in rat liver. Cilobamine methanesulfonate promotes hypertrophy of the smooth endoplasmic reticulum in rat liver hepatocytes, increases relative liver weight and recoverable microsomal protein. Cilobamine methanesulfonate produces stimulant and anxiogenic effects, and does not inhibit monoamine oxidase. Cilobamine methanesulfonate can be used in the research of depression.