Others

Thalidomide-propargyl is an aryl propargyl ether conjugate of Thalidomide (HY-14658).

NNK-d₄ is the deuterium labeled NNK.

Arachidonic acid-Biotin is a biotin-labeled Arachidonic acid (HY-109590) that can be used to detect complexes of arachidonic acid with protein binding partners such as fatty acid binding proteins (FABPs).

trans-Stilbene ((E)-Stilbene) is used in the manufacturing of dye lasers, optical brighteners, non-steroidal synthetic estrogens.

Trypsin, porcine pancreas (Cell culture grade) is a serine protease that hydrolyzes proteins at the carboxyl side of lysine or arginine residues. Trypsin, porcine pancreas (Cell culture grade) exhibits excellent protein digestibility for α-lactalbumin and β-casein. Trypsin, porcine pancreas (Cell culture grade) removes cellular components while preserving extracellular matrix structures to achieve uniform decellularization of porcine pancreas.

Neutral protease I (Dispase I) is a rapid, effective, gentle and neutral protease that can separate intact epidermis from the dermis. Neutral protease I can also separate intact epithelial sheets in culture from the substratum. Neutral protease I preserves the viability of the epithelial cells while cleaving the basement membrane zone region. Neutral protease I can also be used to prevent clumping in suspension cultures. Neutral protease I cleaves fibronectin and type IV collagen, but not laminin, type V collagen, serum albumin, or transferrin.

DP-1, a degradation product of SDC-TRAP-0063, is a fragment of Ganetespib. Ganetespib is a heat shock protein 90 (HSP90) inhibitor with anti-tumor activity.

Myristoyl-L-carnitine-d₃ chloride is the deuterium labeled Myristoyl-L-carnitine chloride (HY-135170). Myristoyl-L-Carnitine Chloride is a natural long-chain glycoline, amino acid derivative.

(±)-Reticuline (compound 3f) is a natural product obtained from Peumus boldus Molina. (±)-Reticuline can be used to synthesize S-Reticuline.

6-FAM-PEG3-Azide is a PEG-modified azide-functionalized fluorescein derivative that is used for labeling oligonucleotides. 6-FAM-PEG3-Azide is also a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. When 6-FAM-PEG3-Azide is co-incubated with boron clusters in a non-covalent manner, it enhances the cellular uptake and membrane permeability of 6-FAM (HY-66021). 6-FAM-PEG3-azide is applicable for fluorescence bioconjugation and probe development-related research.

(S,S)-EDDS is a chelating agent and a structural isomer of EDTA (HY-Y0682), which forms complexes with Co²⁺, Ni²⁺, Cu²⁺, Zn²⁺ and Cd²⁺.

1,N6-Ethenoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

5-Bromo-4-chloro-3-indolyl β-D-glucopyranoside, a chromogenic substrate for the detection of β-galactosidase activity. It is commonly used in molecular biology techniques such as gene expression analysis and reporter gene analysis. When β-galactosidase cleaves X-Gluc, a blue precipitate is produced, which can be observed by microscopy or other detection methods. X-Gluc has high sensitivity and specificity for the detection of β-galactosidase activity, making it a widely used tool in molecular biology research.

3-Indolyl acetate is an ester derivative of indole that is ubiquitous in various plant tissues, especially in certain cruciferous vegetables such as broccoli and cabbage. 3-Indolyl acetate has unique chemical properties that make it an important signaling molecule in plants, regulating various physiological processes such as growth and defense against pathogens. It also has potential applications in the pharmaceutical industry, as it has been shown to have antitumor and anti-inflammatory effects in some studies.

Janelia Fluor 646, Tetrazine (JF646, Tetrazine) a red fluorescent dye that contains a tetrazine group. JF646, Tetrazine can be used in cellular imaging. Janelia Fluor fluorescent dyes can be chemically conjugated to the specific HaloTag substrate (a chloroalkane ligand) to form a fluorescent ligand, rather than binding directly to the HaloTag protein itself. Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Janelia Fluor 646, Tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups (Ex/Em = 646/664 nm).

7-Hydroxywarfarin is a Warfarin analog with anticoagulant activity.

TCO-PNB ester is an amine-reactive motif used for modifying amine-containing molecules. TCO-PNB ester contains a TCO group, which undergoes inverse electron-demand Diels-Alder (iEDDA) reaction with tetrazine-group-containing molecules.

LX2931 is an inhibitor of Sphingosine 1-Phosphate Lyase (S1PL). LX2931 works by increasing levels of S1P inside and outside the cell. The decrease in S1PL activity leads to a significant increase in S1P content in tissues, especially in lymphoid tissues which may lead to a restricted exodus of lymphocytes from secondary immune tissues, resulting in lymphocytopenic and immunosuppressive effects in the peripheral circulation. LX2931 can be used in research for the study of autoimmune diseases, especially rheumatoid arthritis.

18:0 mPEG2000 PE (DSPE-mPEG2000) ammonium is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:0 mPEG2000 PE ammonium can be used for drug delivery.

Vitamin B5-d₄ (calcium) is the deuterium labeled Vitamin B5 calcium.