Others

Multiplex immunohistochemistry (mIHC) Antibody diluent is a special antibody dilution solution for multiplex immunohistochemistry.

BG-PEG-NH₂ (SNAP-PEG-NH₂) is an amino-terminal fluorescent probe building block and a precursor for site-specific labeling of SNAP-tag fusion proteins. BG-PEG-NH₂ undergoes one-step coupling with activated carboxyl esters to form customized SNAP-tag substrates, which covalently bind to SNAP tags via a thioether bond formed at the Cys145 site. After coupling with a caged carboxyfluorescein, BG-PEG-NH₂ forms a probe with Ex/Em = 500/524 nm following ultraviolet uncaging. Coupling of BG-PEG-NH₂ with SeTau-647-NHS enables visualization of GPCR signal transduction. BG-PEG-NH₂ is suitable for coupling reactions in aqueous phases or buffers, conjugation of labels, and labeling of intracellular or cell-surface proteins.

Cy5.5 bis-COOH bromide is a derivative of Cy5.5 (HY-D0924) dye. Sulfo Cy5.5 bis-COOH bromide contains carboxyl groups, which can condense ammonia to form covalent bonds (Ex/Em = 680/710 nm).

Rhodamine-Alginate is a Rhodamine B (HY-Y0016)-labeled alginate. Rhodamine-Alginate combines the polysaccharide properties of alginate with the fluorescence properties of Rhodamine B, playing an important role in fields such as fluorescent labeling, cell imaging, and drug delivery research (Ex/Em = 546/610 nm).

Rhodamine B-Dextran (MW 10000) is a Rhodamine B (HY-Y0016)-labeled dextran with a molecular weight of 10,000. Rhodamine B-Chitosan (MW 10000) plays an important role in fluorescent labeling, cell imaging, vascular imaging, and drug delivery research (Ex/Em = 546/610 nm).

RhoNox-4 is a ferroptosis inhibitor and a fluorescence activation indicator specific to Fe²⁺. RhoNox-4 selectively reacts with labile Fe²⁺ and oxidizes it to Fe³⁺, depleting labile Fe²⁺ involved in lipid peroxidation and inhibiting ferroptosis induced by ferroptosis inducers. RhoNox-4 is cell-permeable, accumulates in the endoplasmic reticulum and/or Golgi apparatus, can be used for live-cell imaging and high-throughput screening of subcellular iron status regulators, and is applicable to iron biology research.

15-Deoxy-Δ12,14-Prostaglandin J2-biotin is a biotin-labled 15-Deoxy-Δ12,14-Prostaglandin J2 (HY-108568). 15-Deoxy-Δ12,14-Prostaglandin J2-biotin is a biotin can be used as a fluorescent probe.

AF 350 NHS ester is a fluorescent dye AF 350 derivative exhibits high fluorescence quantum yield and high photostability. AF 350 NHS ester can form an ester bond with ammonia via the NHS group, and can be used to label proteins, amine-modified oligonucleotides, and other primary amines (R-NH2) containing amine molecules (Ex/Em = 346/445 nm).

MitoCLox is a mitochondria-targeted ratiometric fluorescent probe for measuring mitochondrial inner membrane lipid peroxidation.

pH Receptor Probe (solution) is a pH-sensitive cyanine derivative and a environmental sensitive fluorophore. pH Receptor Probe has a pH-sensitive maximal absorption at 644 nm and emission at 664 nm. pH Receptor Probe has been used as a pH sensor of lysosomal compartments.
Solvent and concentration: DMSO: 10 mM

Fluorescein-5-maleimide (solution) (N-(5-Fluoresceinyl)maleimide (solution)) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm.

Solvent and concentration: DMSO: 10 mM

WST-1 (solution) is a kind of water-soluble tetrazolium salt. WST induces the intracellular mitochondrial dehydrogenase to conduct NADH-dependent enzyme digestion reaction, releasing the water-soluble methyl benzene product. WST-1 can be used for the detection of cell proliferation and cytotoxicity, via the determination of the light absorption value at 450 nm.
Solvent and concentration: ddH2O: 10 mg/mL

Fura-2 AM (solution) (Fura-2 Acetoxymethyl ester (solution)) is a membrane permeable, intracellular, UV light-excitable and ratiometric fluorescent Ca²⁺ (calcium ion) indicator. Fura-2 AM crosses cell membranes and is converted to Fura-2 (HY-D0110A) via cellular esterases. Fura-2 AM can be used to detect calcium in cells.
Solvent and concentration: DMSO: 1 mM

Copper Fluor-4 (solution) (CF4 (solution)) is a Cu⁺-specific fluorescent probe based on a rhodol dye scaffold. Copper Fluor-4 solution has high copper selectivity with a K_d value of 2.9×10^?13 M, particularly over zinc and iron, as well as abundant cellular alkali and alkaline earth metals. Copper Fluor-4 solution is stable in a physiologically relevant pH regime between 6 and 8 (wavelengths of 415 nm for excitation and 660 nm for emission).
Solvent and concentration: DMSO: 5 mM

Collagenase (Type A, filtered, animal free) is a proteolytic enzyme targeting collagen, capable of releasing corneal endothelial cells (CECs) without damaging cell junctions.

Aldose 1-epimerase (mutarotases) is a mutarotase and also a key enzyme in carbohydrate metabolism. Aldose 1-epimerase catalyzes the interconversion between α- and β-anomeric isomers of hexoses including glucose and galactose, with a preference for galactose. Aldose 1-epimerase can be used in studies related to galactosemia.

Peptidase (IMPa) (Erepsin) is catalytically active enzyme that cleaves peptide bonds in proteins and peptides by hydrolysis.

GDP-mannose pyrophosphorylase (ManC) (GDP-MP) is a cytoplasmic protein that catalyzes the formation of GDP-mannose. GDP-mannose pyrophosphorylase (ManC) is the precursor for the mannose residues in glycoconjugates, using mannose 1-phosphate and GTP as substrates.

alpha-2-3,6,8-Sialidosidase (SpNanA) catalyses hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.

alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138) (EC 2.4.1.40(Pm1138)), also namely the ABO system transferase with glycosyl transferase activity.