-
ADC Payloads Related Products (219)
Related Products (219)
-
INX-SM-6
0 ImagesINX-SM-6 can be used for targeted delivery of anti-inflammatory agent. INX-SM-6 inhibits LPS-induced IL-1β production in human PBMCS.
-
Mertansine-d3
0 ImagesCat. No.: HY-19792S2Synonyms: DM1-d3; Maytansinoid DM1-d3Mertansine-d3 (DM1-d3) is the deuterium labeled Mertansine (HY-19792). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. Mertansine can be attached to a monoclonal antibody with a linker to create an antibody-drug conjugate (ADC).
-
7Ethanol-10NH2-11F-Camptothecin
0 ImagesCat. No.: HY-156517CAS No.: 2873460-31-07Ethanol-10NH2-11F-Camptothecin is a Camptothecin (HY-16560) analogue that serves as an ADC cytotoxin for the synthesis of antibody-drug conjugates (ADCs). 7Ethanol-10NH2-11F-Camptothecin can inhibit tumor growth and is used in cancer research.
-
PBD derivative-1
0 ImagesCat. No.: HY-178270CAS No.: 2305851-17-4PBD derivative-1 (Compound 7-8) is a derivative of PBD, and PBD is the payload in antibody-drug conjugates (ADCs). PBD derivative-1 can be used for the synthesis of ADCs.
-
Cy3.5 maleimide
0 ImagesCat. No.: HY-D2231Cy3.5 maleimide is a relatively water-soluble fluorescent dye. Cy3.5 maleimide is soluble in organic solvents, including DMF, DMSO and acetonitrile and so on.
-
(S,S)-D211
0 ImagesCat. No.: HY-122715CAS No.: 1971075-99-6(S,S)-D211 is a stereoisomer of D211. (S,S)-D211 belongs to PBD dimer family with DNA damage activity. (S,S)-D211 can be used as a cytotoxic payload for synthesis of antibody-drug conjugates (ADCs).
-
MMAF-methyl ester
0 ImagesCat. No.: HY-W190923CAS No.: 2353409-70-6MMAF-methyl ester is a methylated derivative of the tubulin inhibitor MMAF (HY-15579), and serves as a pharmaceutical intermediate for the development of antibody-drug conjugates (ADCs) and small-molecule drug conjugates (SMDCs).
-
Hemiasterlin derivative-1
0 ImagesCat. No.: HY-145148CAS No.: 1887046-60-7Hemiasterlin derivative-1 is a hemiasterlin derivative. Hemiasterlin derivative-1 can be used for the synthesis of the antibody-drug conjugate (ADC).
-
L2H2-6OTD
0 ImagesCat. No.: HY-148200CAS No.: 1016263-75-4L2H2-6OTD, containing one to four G-quadruplex binding loops, is a telomeric inhibitor analogue. l2H2-6OTD has telomerase inhibitory activity with an IC50 value of 15 nM.
-
PBD dimer-4
0 ImagesCat. No.: HY-175004CAS No.: 1821339-88-1PBD dimer-4 (Compound 7) is a C1-subsitituted PBD dimer. PBD dimer-4 has high DNA-binding affinity, DNA cross-linking ability and potent cytotoxicity against MDA-MB-231 cells (IC50: 236 nM). PBD dimer-4 can be used as a payload of ADC Loncastuximab tesirine (HY-P99349) to treat several different cancer types.
-
(R)-thioxo-Dxd
0 ImagesCat. No.: HY-178262CAS No.: 2806052-36-6(R)-thioxo-Dxd is a Camptothecin (HY-16560) derivative. (R)-thioxo-Dxd can be connected to monoclonal antibodies via linkers to form antibody-drug conjugate (ADC) molecules. (R)-thioxo-Dxd can be used for research on tumors with high HER2 or TROP2 expression.
-
Daunorubicin (Standard)
0 ImagesCat. No.: HY-13062ARCAS No.: 20830-81-3Synonyms: Daunomycin (Standard); RP 13057 (Standard); Rubidomycin (Standard)Daunorubicin (Standard) is the analytical standard of Daunorubicin (HY-13062A). This product is intended for research and analytical applications. Daunorubicin (Daunomycin) is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin inhibits DNA and RNA synthesis. Daunorubicin is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin is also an anthracycline antibiotic. Daunorubicin can be used in the research of infection and variety of cancers, including leukemia, non-HodgKin lymphomas, Ewing's sarcoma, Wilms' tumor.
-
Exatecan Intermediate 1 (Standard)
0 ImagesExatecan Intermediate 1 (Standard) is the analytical standard of Exatecan Intermediate 1. This product is intended for research and analytical applications. Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (HY-13631). Exatecan is a DNA topoisomerase I inhibitor with anticancer effects.
-
Budesonide-d6
0 ImagesCat. No.: HY-W742981CAS No.: 1134189-63-1Budesonide-d6 is deuterium labeled Budesonide. Budesonide, an inhaled glucocortical steroid, is an orally active glucocorticoid receptor agonist. Budesonide decreases the size of lung tumors, reverses DNA hypomethylation and modulates mRNA expression of genes. Budesonide is an anti-inflammatory agent used for asthma.
-
Antiproliferative agent-81
0 ImagesCat. No.: HY-189369Antiproliferative agent-81 is a Homocamptothecin-derived ADC payload (ADC Payload) featuring an expanded seven-membered β-hydroxylactone ring. Antiproliferative agent-81 exhibits antiproliferative activity against multiple cancer cell lines with varying HER2 expression levels. Antiproliferative agent-81 is applicable to ADC synthesis-related research.
