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Antibodies (14)
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JAK05
0 ImagesCat. No.: HY-170586JAK05 exhibits inhibitory activity against Helicobacter pylori, inhibits strains J63, J196 and J107 with MIC of 3-5 µg/mL. JAK05 exhibits binding affinity to H+/K+-ATPase, COX-1/2, TNF-α and PGE2, reveals antioxidant and anti-inflammatory activities. JAK05 exhibits anti-ulcer activity in rat ethanol-induced gastric ulcer models. -
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Ethyl acetoacetate-13C2
0 ImagesCat. No.: HY-Y1093SCAS No.: 77504-73-5Synonyms: Ethyl acetylacetate-13C2; EAA-13C2Ethyl acetoacetate-13C2 (Ethyl acetylacetate-13C2) is the 13C-labeled Ethyl acetoacetate. Ethyl acetoacetate (Ethyl acetylacetate) is an ester widely used as an intermediate in the synthesis of many varieties of compounds. Ethyl acetoacetate is an inhibitor of bacterial biofilm. -
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β-Alanine-pyruvate transaminase
0 ImagesCat. No.: HY-P3170CAS No.: 61461-61-8β-alanine-pyruvate transaminase is an enzyme. Dihydrouracil and dihydrothymine, as nitrogen sources, increase the activity of β-alanine-pyruvate transaminase in cultured B. cepacia cells. The activity of β-alanine-pyruvate transaminase can be measured by tracking the release of L-α-alanine during the reaction. -
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Anti-MRSA agent 3
0 ImagesCat. No.: HY-144823CAS No.: 2416909-42-5Anti-MRSA agent 3 (compound 18) has highly inhibitory activity against Methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.098 μg/ml, and low cytotoxicity in normal cells. Anti-MRSA agent 3 has relatively strong ability to destroy bacterial cell wall and membrane, high binding affinity to bacterial genomic DNA. -
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Fumagillol (Standard)
0 ImagesCat. No.: HY-103643RCAS No.: 108102-51-8Synonyms: (-)-Fumagillol (Standard)Glucotropaeolin (potassium) (Standard) is the analytical standard of Glucotropaeolin (potassium). This product is intended for research and analytical applications. Glucotropaeolin potassium (Benzylglucosinolate potassium) , a glucosinolate contained in cruciferous vegetables, causes a moderate decrease in spontaneous DNA damage in animals. -
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Anti-MRSA agent 2
0 ImagesCat. No.: HY-144822CAS No.: 2597082-01-2Anti-MRSA agent 2 (compound 14) has highly inhibitory activity against Methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.098 μg/ml, and relatively low cytotoxicity in normal cells. Anti-MRSA agent 2 has strong ability to destroy bacterial membrane and bind to genomic DNA. -
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Vitamin K5
0 ImagesVitamin K5 (Synkamin) is a photosensitizer and a antimicrobial agent. Vitamin K5 is a specific PKM2 inhibitor with IC50 values of 28, 191 and 120 μM for PKM2, PKM1 and PKL. Vitamin K5 induces apoptosis of colon 26 cells. Vitamin K5 can be used for the research of infection and cancer, and it also can be used as a preservative for pharmaceuticals, foods, and beverages. -
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Calendula extract
0 ImagesCat. No.: HY-N18644CAS No.: 84776-23-8The main active ingredients of calendula extract are lutein and zeaxanthin. It has anti-aging, anti-inflammatory and antibacterial effects. It also has a certain moisturizing effect, thus can be used as a good functional cosmetics raw material. -
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N-Formylfortimicin A
0 ImagesCat. No.: HY-N7224CAS No.: 74228-81-2Synonyms: SF-1854N-Formylfortimicin A (SF-1854) is an aminoglycoside antibiotic with broad-spectrum antibacterial activity. It primarily acts on bacterial ribosomes to inhibit protein synthesis and exhibits notable inhibitory effects against various Gram-positive and Gram-negative bacteria (e.g., E. coli with a MIC of 12.5-50 μg/mL), making it a potential candidate for research on bacterial infection-related diseases. -
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Arbekacin
0 ImagesCat. No.: HY-B2094CAS No.: 51025-85-5Arbekacin, an aminoglycoside antibiotic, exhibits broad antimicrobial activities against not only Gram-positive bacteria but also Gram-negative bacteria. -
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(E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium trifluoromethanesulfonate
0 ImagesCat. No.: HY-173163CAS No.: 2811663-45-1(E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium (trifluoromethanesulfonate) (Compound 4a) is a Gram-negative outer membrane permeabilizer with synergistic antibacterial activity through the blockage on LptA/LptC interaction via targeting Met47 in LptA. (E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium (trifluoromethanesulfonate) potentiates pol B against both wild-typed and MDR A. baumannii and E. coli strains. (E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium (trifluoromethanesulfonate) can be used as antibiotic adjuvants against MDR Gram-negative bacteria. -
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N-Myristoyl-D-asparagine
0 ImagesCat. No.: HY-N18530CAS No.: 1439789-50-0N-Myristoyl-D-asparagine is a key metabolic marker in the biosynthesis and maturation of colibactin. N-Myristoyl-D-asparagine acts as a biomarker for detecting colibactin. N-Myristoyl-D-asparagine exhibits mild growth inhibitory activity against Bacillus subtilis NCIB 3610. -
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D-Arabinose-d6
0 ImagesCat. No.: HY-N0059S6D-Arabinose-d6 is the deuterated-labeled D-Arabinose (HY-N0059). D-Arabinose is is an orally active antidepressant and a growth inhibitor of C. elegans (IC50 is 7.5 mM). D-Arabinose can penetrate the blood-brain barrier, selectively interfere with the metabolism of D-ribose and D-fructose, and inhibit the growth of nematodes. D-Arabinose can also inhibit the synthesis of cell biofilm and exert antibacterial activity. D-Arabinose activates the ACSS2-PPARγ/TFEB-CRTC1 axis through the lysosomal AXIN-LKB1-AMPK pathway, inducing CRTC1 transcription, exerts antidepressant-like activity. D-Arabinose is the ring-opened form of the aldopentose D-Arabinose (HY-N7082). -
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Cefempidone
0 ImagesCat. No.: HY-105981CAS No.: 103238-57-9Synonyms: GR 50692; TA 5901Cefempidone (GR 50692) is a third-generation cephalosporin antibiotic. Cefempidone exerts antibacterial activity by inhibiting penicillin-binding proteins in bacterial cell wall synthesis. -
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Antimycobacterial agent-8
0 ImagesCat. No.: HY-161890Antimycobacterial agent-8 (Compound 49) is an inhibitor for DNA gyrase. Antimycobacterial agent-8 exhibits antibacterial activity against Mycobacterium tuberculosis and M. abscessus with MIC90 of 2.5 μM and 0.63 μM. Antimycobacterial agent-8 exhibits good plasma protein binding ability in mice. -
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Cefamandole lithium
0 ImagesCat. No.: HY-B1128BCAS No.: 58648-57-0Synonyms: Cephamandole lithiumCefamandole (Cephamandole) lithium is a semi-synthetic second-generation cephalosporin antibiotic with broad-spectrum antimicrobial activity. Cefamandole lithium is resistant to hydrolysis by β-lactamases produced by some Gram-negative bacteria. Cefamandole lithium kills Gram-positive cocci and various Gram-negative bacilli mainly by inhibiting cell wall synthesis, but it is inactive against Pseudomonas, Proteus vulgaris and Providencia stuartii, and its efficacy is affected by inoculum size. The plasma elimination half-life of Cefamandole lithium in rats is only 0.4 h, it is mainly excreted in urine in biologically active form, and it hardly penetrates the non-inflamed blood-brain barrier. Cefamandole lithium is widely used in studies related to bacterial infections. -
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SCUT1-2
0 ImagesCat. No.: HY-172768CAS No.: 2930140-57-9SCUT1-2 is a bifunctional antibacterial agent with good oral bioavailability in mice (F=56.8%). SCUT1-2 can kill the vegetative cells of C. difficile with a MIC of 0.06-0.50 μg/mL, and inhibit spore germination in vitro. SCUT1-2 could alleviate the symptoms of weight loss and diarrhea in mice caused by C. difficile infection (CDI) and prevent recurrent CDI. -
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NSC177365
0 ImagesCat. No.: HY-122069CAS No.: 80261-18-3Synonyms: NSC 1NSC177365 (NSC 1) is a CcrM inhibitor. NSC177365 is a competitive DNA inhibitor and disrupts DNA binding. NSC177365 has antibacterial activity, with IC50s of 2.3 and 14.6 μM for C. crescentus and M. lincolnii respectively. NSC177365 reverses several neurodegenerative disorders and serve as an anticancer agent. -
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Resorcinomycin A
0 ImagesCat. No.: HY-N14589CAS No.: 100234-70-6Resorcinomycin A is an antibiotic with strong anti-mycobacterium effect and weak anti-mycoplasma effect. -
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Paenilagicin
0 ImagesCat. No.: HY-P10210Paenilagicin is a Gram-positive active antibiotic with a unique diphosphorylated prenyl binding mechanism that does not induce drug resistance. Paenilagicin exhibits a MIC value of 2 μg/mL against multidrug-resistant Gram-positive bacteria. -
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