Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2569)
Related Products (2569)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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UA2239
0 ImagesCat. No.: HY-179656CAS No.: 2455422-89-4UA2239 is an antimalarial agent and acyclic nucleoside phosphonate. UA2239 disrupts the essential cGMP-dependent egress pathway by decreasing cGMP levels. UA2239 targets guanylyl cyclase α. UA2239 demonstrates rapid and irreversible inhibitory effects on Plasmodium parasites.
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Antimalarial agent 37
0 ImagesCat. No.: HY-161171CAS No.: 2982633-16-7Antimalarial agent 37 (compound 33) is a selective inhibitor against Type Ⅱ kinase with antiplasmodial activity. Antimalarial agent 37 exhibited cytotoxicity and selectivity towards cancer cells HepG2 and MCF 7.
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Toltrazuril sulfoxide (Standard)
0 ImagesCat. No.: HY-136438RCAS No.: 69004-15-5Toltrazuril sulfoxide (Standard) is the analytical standard of Toltrazuril sulfoxide. This product is intended for research and analytical applications. Toltrazuril sulfoxide is a short-lived intermediary metabolite of Toltrazuril (HY-B0175), and then can be metabolized to the reactive toltrazuril sulfone (TZR-SO2) in vivo. Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites.
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Antitrypanosomal agent 10
0 ImagesCat. No.: HY-151942Antitrypanosomal agent 10 is an antitrypanosomal agent that inhibits Trypanosoma cruzi with an IC50 of 0.28 μM.
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SKF-83566 hydrochloride
0 ImagesCat. No.: HY-103430BCAS No.: 164265-49-0SKF-83566 hydrochloride is an orally active, blood-brain barrier-permeable D1/D5 dopamine receptor antagonist with a Ki value of approximately 0.4-0.56 nM. SKF-83566 hydrochloride modulates locomotor behavior and spatial memory by blocking D1 receptors and inhibits glioblastoma progression by targeting the DRD1/c-Myc/UHRF1 pathway. SKF-83566 hydrochloride acts as an inhibitor of the dopamine transporter (DAT) and adenylyl cyclase 2 (AC2). SKF-83566 hydrochloride competitively binds to DAT to inhibit dopamine reuptake and non-competitively inhibits AC2 activity, thereby reducing cAMP accumulation. SKF-83566 hydrochloride is used in research areas such as dopaminergic system mechanisms, learning and memory, targeted intervention for glioblastoma, AC2 pathophysiology, antiparasitic drug screening, and synaptic plasticity (the "gating effect").
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3β-Hydroxy-hop-22(29)-ene
0 ImagesCat. No.: HY-N10441CAS No.: 58801-23-33β-Hydroxy-hop-22(29)-ene (compound 3) is a potent antiparasitic agent. 3β-Hydroxy-hop-22(29)-ene shows moderate activity against Trypanosoma cruzi and Leishmania mexicana.
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Artesunate-d4
0 ImagesCat. No.: HY-N0193S1CAS No.: 1316753-15-7Artesunate-d4 is deuterium labeled Artesunate. Artesunate is an inhibitor of both STAT-3 and exported protein 1 (EXP1).
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Nitidine chloride (Standard)
0 ImagesCat. No.: HY-N0498RCAS No.: 13063-04-2Nitidine (chloride) (Standard) is the analytical standard of Nitidine (chloride). This product is intended for research and analytical applications. Nitidine chloride, a potential anti-malarial lead compound derived from Zanthoxylum nitidum (Roxb) DC, exerts potent anticancer activity through diverse pathways, including inducing apoptosis, inhibiting STAT3 signaling cascade, DNA topoisomerase 1 and 2A, ERK and c-Src/FAK associated signaling pathway. Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kB pathway.
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CDA-IN-3
0 ImagesCat. No.: HY-172523CAS No.: 932889-57-1CDA-IN-3 (NCDI) is an inhibitor of chitin deacetylase (CDA) with anti-parasitic activity. CDA-IN-3 disrupts the chitin metabolism of nematodes, leading to an increase in the level of ROS in nematodes and causing cell damage. CDA-IN-3 has a significant inhibitory effect on all developmental stages of Caenorhabditis elegans. CDA-IN-3 can be used in the research of the anti-infection field .
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Dapsone-d4
0 ImagesCat. No.: HY-B0688S1CAS No.: 1346602-12-7Synonyms: 4,4′-Diaminodiphenyl sulfone-d4; DDS-d4Dapsone-d4 is the deuterium labeled Dapsone. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al.
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Antimalarial agent 7
0 ImagesCat. No.: HY-145327CAS No.: 2756414-77-2Antimalarial agent 7 is a potent inhibitor of PfATP4. PfATP4 is an essential ion pump on the parasite surface. Antimalarial agent 7 has the potential for the research of human malaria parasite, Plasmodium falciparum.
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Antileishmanial agent-37
0 ImagesCat. No.: HY-178784Antileishmanial agent-37 (Compound 1b) is an antileishmanial agent, TbPTR1 (an IC50 value of 17.1 μM) and LmPTR1 inhibitor. Anti-leishmaniasis agent-37 has a moderate effect against Leishmania infantum.
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Malonomicin
0 ImagesCat. No.: HY-121405CAS No.: 38249-71-7Synonyms: Antibiotic K16Malonomicin (Antibiotic K16) is an antibiotic with anti-protozoa and anti-trypanosome activities. Malonomicin also shows anti-trypanosome activity in vivo.
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(R)-Meclonazepam
0 ImagesCat. No.: HY-101725ACAS No.: 86630-81-1Synonyms: Ro 11-3624; Ro 11-3624/001(R)-Meclonazepam (Ro 11-3624) is an inactive enantiomer of Meclonazepam. Meclonazepam is a benzodiazepine derivative with anti-schistosomiasis activities.
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10-Propoxydecanoic acid
0 ImagesCat. No.: HY-118324CAS No.: 119290-12-9Synonyms: O-11; 11-Oxatetradecanoic acid10-Propoxydecanoic acid (compound 011) is a toxic myristate analog with an IC50 value of 14μM on KETRI 243.
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Antileishmanial agent-14
0 ImagesCat. No.: HY-149093CAS No.: 1638956-72-5Antileishmanial agent-14 is a sulfuretin analog with potential activity against the parasite Leishmania donovani promastigotes (IC50=4.1 μM). Antileishmanial agent-14 also inhibits infection by L. donovani amastigotes (IC50=11.1 μM).
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Hederacholchiside E
0 ImagesCat. No.: HY-107311CAS No.: 33783-82-3Hederacholchiside E (compound 6) is a kind of saponin. Hederacholchiside E can be isolated from the Anemone raddeana.
