Renin Inhibitor

Renin Inhibitors (26):

Cat. No.	Product Name	Effect	Purity

HY-12176

Aliskiren	Inhibitor	99.24%
Aliskiren is an orally active, highly potent and selective renin inhibitor, with IC₅₀ of 1.5 nM. Aliskiren can be used for the research of hypertension, cardiovascular diseases and cancer cachexia.

HY-12177

Aliskiren hemifumarate	Inhibitor	99.80%
Aliskiren (CGP 60536; CGP60536B; SPP 100) hemifumarate is an orally active and selective renin inhibitor, with IC₅₀ of 1.5 nM. Aliskiren hemifumarate can be used for the research of hypertension, cardiovascular diseases and cancer cachexia.

HY-151111

SPH3127	Inhibitor	98.26%
SPH3127 (DRI 18) is a novel, highly potent, and orally active direct renin inhibitor (recombinant human-renin IC₅₀=0.4 nM, human plasma renin activity IC₅₀=0.45 nM). SPH3127 shows antihypertensive effect and can be used in essential hypertension research.

HY-N2115

Araloside A	Inhibitor	98.31%
Araloside A (Chikusetsusaponin IV) is a component of Panax japonicus, with low-renin-inhibitory activity, with an IC₅₀ of 77.4 μM.

HY-76652

VTP-27999 Hydrochloride	Inhibitor	98.18%
VTP-27999 Hcl is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases.

HY-120673

SQ 32970	Inhibitor
SQ 32970 is a tripeptidic renin inhibitor. SQ 32970 potently inhibits endothia protease.

HY-P2130

SR 42128	Inhibitor
SR 42128 is a potent renin inhibitor. SR 42128 potently inhibits primate renins whereas other animal renins are much less inhibited.

HY-129695

PD 132002	Inhibitor
PD 132002 is an orally active, potent renin inhibitor. PD 132002 weakly inhibits pepsin. PD 132002 produces substantial reductions in blood pressure.

HY-50769

VTP-27999 TFA	Inhibitor
VTP-27999 TFA is an alkyl amine Renin inhibitor; VTP-27999 TFA is useful for Hypertension and End-Organ Diseases.

HY-N9528

Lyciumin A	Inhibitor	≥99.0%
Lyciumin A, a cyclic octapeptide, exhibits inhibitory activity on proteases, renin and angiotensin-converting enzyme. Lyciumin A can be used for the research of hypertension.

HY-12176B

Aliskiren fumarate	Inhibitor
Aliskiren fumarate is an orally active, highly potent and selective renin inhibitor, with IC₅₀ of 1.5 nM. Aliskiren fumarate can be used for the research of hypertension, cardiovascular diseases and cancer cachexia.

HY-12176A

Aliskiren hydrochloride	Inhibitor
Aliskiren (CGP 60536; CGP60536B; SPP 100) hydrochloride is an orally active and selective renin inhibitor, with IC₅₀ of 1.5 nM. Aliskiren hydrochloride can be used for the research of hypertension, cardiovascular diseases and cancer cachexia^-.

HY-B1562C

Bopindolol fumarate	Inhibitor
Bopindolol ((±)-Bopindolol) fumarate is an orally active antagonist of β-adrenoceptors (ARs) with partial agonist activity. Bopindolol fumarate is non-selective for β1- and β2-ARs and has low affinity for β3-AR subtype. Bopindolol fumarate has intrinsic sympathomimetic as well as membrane stabilizing actions, inhibits renin secretion, and interacts with 5-HT receptors. Bopindolol fumarate is a proagent of Pindolol (HY-B0982). Bopindolol fumarate can be used for essential and renovascular hypertension research.

HY-50768

VTP-27999	Inhibitor
VTP-27999 is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases.

HY-B1562B

Bopindolol (malonate)	Inhibitor
Bopindolol ((±)-Bopindolol) malonate is an orally active antagonist of β-adrenoceptors (ARs) with partial agonist activity. Bopindolol malonate is non-selective for β1- and β2-ARs and has low affinity for β3-AR subtype. Bopindolol malonate has intrinsic sympathomimetic as well as membrane stabilizing actions, inhibits renin secretion, and interacts with 5-HT receptors. Bopindolol malonate is a proagent of Pindolol (HY-B0982). Bopindolol malonate can be used for essential and renovascular hypertension research.

HY-105205

Terlakiren	Inhibitor
Terlakiren (CP-80,794) is an orally active inhibitor of renin. Terlakiren inhibits the efficacy of human renin with an IC₅₀ value of 0.7 nM. Terlakiren has potential applications in hypertension.

HY-12176AS

Aliskiren-d₆ hydrochloride	Inhibitor
Aliskiren-d₆ (hydrochloride) is is deuterium labeled Aliskiren, which is a direct renin inhibitor.

HY-P5388

Renin inhibitor peptide,rat	Inhibitor
Renin inhibitor peptide,rat is a biological active peptide. (A specific rat renin inhibitor.)

HY-105276

Enalkiren	Inhibitor
Enalkiren (A-64662) is a potent dipeptide renin inhibitor with an IC₅₀ of 0.78 nM in a purified renal renin-angiotensinogen system (pH=6.0). Enalkiren suppresses renin activity, and also reduces systolic and diastolic blood pressure. Enalkiren can be used to research essential hypertension.

HY-12177S

Aliskiren-d₆ hemifumarate	Inhibitor
Aliskiren-d₆ (hemifumarate) is a deuterium labeled Aliskiren hemifumarate. Aliskiren hemifumarate is a direct and orally active renin inhibitor with an IC50 of 1.5 nM[1][2].

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