2. Signaling Pathways
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  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3822):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W725181
    Methyl 2-phenyl-2-(pyrrolidin-1-yl)acetate hydrochloride
    		Control
    Methyl 2-phenyl-2-(pyrrolidin-1-yl)acetate hydrochloride is structurally similar to known stimulants.
    Methyl 2-phenyl-2-(pyrrolidin-1-yl)acetate hydrochloride
  • HY-W190972
    3-(3-Nitrophenyl)-5-phenyl-1,2,4-oxadiazole
    3-(3-Nitrophenyl)-5-phenyl-1,2,4-oxadiazole is a PEG derivative containing a tert-butyl ester and an azide group.
    3-(3-Nitrophenyl)-5-phenyl-1,2,4-oxadiazole
  • HY-121434
    N-Deacetylcolchicine
    		98.38%
    N-Deacetylcolchicine is a microtubule polymerization inhibitor with an IC50 of 3 μM against bovine brain microtubules. N-Deacetylcolchicine is a derivative of Colchicine (HY-16569). N-Deacetylcolchicine can activate the GTPase activity of microtubules and can be used for the research of cancer.
    N-Deacetylcolchicine
  • HY-170717
    3-Methylnordiazepam
    3-Methylnordiazepam (RO-5-2751) is a benzodiazepine and shows anticonvulsant activity in mice.
    3-Methylnordiazepam
  • HY-157180
    WAY-327131
    		98.0%
    WAY-327131 is an active molecule.
    WAY-327131
  • HY-W753557
    Avocadene
    Avocadene is a natural product isolated from Persea americana leaves, with anticancer, insecticidal, anti-Helicobacter pylori, and anti-inflammatory activity. Avocadene exerts antibacterial and anti‑inflammatory effects by suppressing Helicobacter pylori growth and inhibiting protein denaturation. Avocadene displays obvious cytotoxic activity against human prostate cancer PC‑3 cells with an IC50 of 0.5 μg/mL. Avocadene can be used for research of Helicobacter pylori‑associated gastrointestinal inflammation, gastroduodenal injury and prostate tumors.
    Avocadene
  • HY-W016470
    9,10-Dihydrophenanthrene
    9,10-Dihydrophenanthrene is an analogue of 9,10-Phenanthrenequinone (HY-W014507). 9,10-Dihydrophenanthrene loses its anti-tumor activity that induces apoptosis in HCT-116 and HL-60 tumor cells.
    9,10-Dihydrophenanthrene
  • HY-U00204
    Nisobamate
    Nisobamate (W1015) is a tranquilizer.
    Nisobamate
  • HY-U00358
    Compound 2
    Compound 2 is an active compound used for the research of metabolic bone diseases.
    Compound 2
  • HY-U00020
    AU-224
    AU-224 is a benzamide derivative used as a promising gastrointestinal prokinetic agent without significant side effects.
    AU-224
  • HY-U00127
    Pyridazinediones-derivative-1
    Pyridazinediones-derivative-1 has potential in treating neurodegenerative disorders. It shows an ED50 of 2.1 μM for inhibiting glutamate-induced contractions of isolated guineapig ileum.
    Pyridazinediones-derivative-1
  • HY-U00059
    Pyrrole-derivative1
    Pyrrole-derivative1 is extracted from patent WO/2002/085851A1, example 2, developed for the treatment of diabetic disease.
    Pyrrole-derivative1
  • HY-U00332
    Hydrocarbon chain derivative 1
    Hydrocarbon chain derivative 1 is an active compound, with inhibitory activities against lipid synthesis.
    Hydrocarbon chain derivative 1
  • HY-U00409
    Antiasthmatic Compound 1
    Antiasthmatic Compound 1 is an antiasthmatic agent, which has the potential for allergic asthma treatment.
    Antiasthmatic Compound 1
  • HY-U00378
    Glycerol derivative 1
    Glycerol derivative 1 is a Glycerol derivative extracted from patent EP 672415 A1, compound (1).
    Glycerol derivative 1
  • HY-U00278
    Deloxolone
    Deloxolone has the potential for inflammatory, ischemic and proliferative diseases treatment.
    Deloxolone
  • HY-U00301
    Anti-hypertensive sulfonanilide 1
    Anti-hypertensive sulfonanilide 1 is a potent antihypertensive agent extracted from patent EP0338793A2, compound XVIIIa,b*, example No.1.
    Anti-hypertensive sulfonanilide 1
  • HY-U00109
    Piridocaine hydrochloride
    Piridocaine hydrochloride (Lucaine hydrochloride) is a piperidyl propanol ester of orthoaminobenzoic acid.
    Piridocaine hydrochloride
  • HY-U00122
    Antiulcer Agent 1
    Antiulcer Agent 1 is a 2-(3,4-dimethoxyphenyl)ethylamine derivative for oral administration at an exploratory stage of new agent development.
    Antiulcer Agent 1
  • HY-U00323
    Carbazole derivative 1
    Carbazole derivative 1 is a carbazole derivative which can be used to reduce androgen or oestrogen levels in mammals, including humans.
    Carbazole derivative 1