Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10876):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-124410S

Mitoquinol-d₁₅
Mitoquinol-d₁₅ is deuterium labeled Mitoquinol (HY-124410). Mitoquinol is an orally active mitochondria-targeted antioxidant. Mitoquinol can regulate mitochondrial respiration and oxidation. Mitoquinol inhibits ROS production, and improves phagocytosis and glycolysis in ethanol-exposed macrophages via the HIF-1α-PFKP axis. Additionally, Mitoquinol can partially alleviate heat stress-induced decreases in growth performance, inflammatory responses, and metabolic disorders in pigs.

HY-B0017S

Telbivudine-d₄
Telbivudine-d₄ is deuterium labeled Telbivudine. Telbivudine (Epavudine), an orally active thymidine nucleoside analog, is a potent antiviral inhibitor of hepatitis B virus (HBV) replication.

HY-Y0383S2

Dimethyl terephthalate-¹³C₂-1
Dimethyl terephthalate-¹³C₂-1 is ¹³C labeled Dimethyl terephthalate. Dimethyl terephthalate is a low toxicity, low volatility industrial chemical widely used in the production of polyester fibers and films.

HY-W717545

Nor Mianserin (Major)-d6
Nor Mianserin (Major)-d₆ is the deuterium labeled 1,2,3,4,10,14b-Hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine (HY-W702070).

HY-N7082S

D-Arabinopyranose-¹³C₅		99.9%
D-Arabinopyranos-¹³C₅ is ¹³C labeled D-Arabinopyranos (HY-N7082). D-Arabinopyranose is a rare aldehyde pentose, and its ring-opened form is D-arabinose (HY-N0059). D-arabinose is is an orally active antidepressant and a growth inhibitor of C. elegans (IC₅₀ is 7.5 mM). D-arabinose can penetrate the blood-brain barrier, selectively interfere with the metabolism of D-ribose and D-fructose, and inhibit the growth of nematodes. D-arabinose can also inhibit the synthesis of cell biofilm and exert antibacterial activity. D-arabinose activates the ACSS2-PPARγ/TFEB-CRTC1 axis through the lysosomal AXIN-LKB1-AMPK pathway, inducing CRTC1 transcription, exerts antidepressant-like activity. D-arabinose is the ring-opened form of the aldopentose D-?Arabinose (HY-N7082).

HY-W002004S

4-Amino-TEMPO-d₁₇,¹⁵N
4-Amino-TEMPO-d₁₇,¹⁵N (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d₁₇,¹⁵N) is the deuterium labeled 4-Amino-TEMPO-d₁₇ (HY-W002004S1). 4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others.

HY-113209S2

8-Isoprostaglandin F2α-¹³C₅
8-Isoprostaglandin F2α-¹³C₅ is ¹³C labeled 8-Isoprostaglandin F2α (HY-113209). 8-Isoprostaglandin F2α is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. 8-Isoprostaglandin F2α is present in human plasma in two distinct forms - esterified in phospholipids and as the free acid. 8-Isoprostaglandin F2α is a weak TP receptor agonist in vascular smooth muscle.

HY-Y0946S

Acetamide-¹⁵N		99.0%
Acetamide-¹⁵N is the ¹⁵N-labeled Acetamide. Acetamide is used as an intermediate in the synthesis of methylamine, thioacetamide, and insecticides, and as a plasticizer in leather, cloth and coatings. Acetamide has carcinogenicity.

HY-W738270

Veratraldehyde-¹³C
Veratraldehyde-¹³C (3,4-Dimethoxy[7-¹³C]-benzaldehyde) is the ¹³C-labeled Veratraldehyde (HY-N1096). Veratraldehyde is an orally active aromatic compound and antibacterial agent. Veratraldehyde can be isolated from essential oils of plants such as peppermint and ginger. Veratraldehyde targets the PilY1 protein. Veratraldehyde has antibacterial activity against Pseudomonas aeruginosa. Veratraldehyde has a repellent effect against mosquitoes and ticks. Veratraldehyde can be used as a flavoring agent.

HY-133695S2

Florfenicol amine-d₅
Florfenicol amine-d₅ is the deuterium labeled Florfenicol amine (HY-133695). Florfenicol amine is a metabolite of Florfenicol (HY-B1374). Florfenicol, a veterinary antibiotic, can be used in aquaculture to control susceptible bacterial diseases.

HY-W719338

Pentane-1,2-diol-d₇
Pentane-1,2-diol-d₇ ((±)-Pentane-1,2-diol-d₇; 1,2-Dihydroxypentane-d₇; 1,2-Pentylene glycol-d₇; Diol PD-d₇; Hydrolite 5-d₇; NSC 513-d₇; 1,2-Pentanediol-d₇) is the deuterium labeled Pentane-1,2-diol (HY-Y1249).

HY-131113S1

N-Nitrosodibutylamine-d₉
N-Nitrosodibutylamine-d₉ is the deuterium labeled N-Nitrosodibutylamine. N-Nitrosodibutylamine (N-Nitroso-di-n-butylamine) is a nitrosamine enriched in the drinking water.

HY-W015971S

1-Methylureal-d₆
1-Methylureal-d₆ is the deuterium labeled 1-Methylurea.

HY-W011188S

Glycidyl stearate-d₅
Glycidyl stearate-d₅ is a deuterium labeled Glycidyl stearate (HY-W011188). Oxiran-2-ylmethyl stearate is a compound belonging to the class of esters. It contains reactive oxirane or epoxy groups that give the molecule its unique properties. Oxiran-2-ylmethyl stearate is derived from stearic acid and epichlorohydrin, which are naturally occurring substances. Glycidyl stearate is commonly used in various industrial applications such as the production of coatings, adhesives and surfactants. It can also be used as a crosslinking agent in the manufacture of polymers and resins.

HY-146940S

CER7-2’S,6R-d₉
CER7-2’S,6R-d₉ is deuterium labeled CER7-2’S,6R.

HY-W724384

1-Bromotridecane-d₉
1-Bromotridecane-d₉ (Tridecyl Bromide-d₉) is the deuterium labeled 1-Bromotridecane.

HY-B0006S2

Carvedilol-d₅
Carvedilol-d₅ is deuterium labeled Carvedilol. Carvedilol (BM 14190) is a non-selective β/α-1 blocker. Carvedilol inhibits lipid peroxidation in a dose-dependent manner with an IC₅₀ of 5 μM. Carvedilol is a multiple action antihypertensive agent with potential use in angina and congestive heart failure. Carvedilol is an autophagy inducer that inhibits the NLRP3 inflammasome.

HY-W585827S1

2-Chloro-1,3-propanediol-d₅ (major)
2-Chloro-1,3-propanediol-d5 (major) is a deuterated labeled 2-Chloro-1,3-propanediol.

HY-W801479S

Edaravone sulfate-d₅
Edaravone sulfate-d₅ is the deuterium labeled Edaravone sulfate. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator.

HY-14588S2

Lopinavir-d₇
Lopinavir-d₇ is deuterated labeled Lopinavir (HY-14588). Lopinavir (ABT-378) is a highly potent, selective peptidomimetic inhibitor of the HIV-1 protease, with K_is of 1.3 to 3.6 pM for wild-type and mutant HIV protease. Lopinavir acts by arresting maturation of HIV-1 thereby blocking its infectivity. Lopinavir is also a SARS-CoV 3CL^pro inhibitor with an IC₅₀ of 14.2 μM.

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