2. Signaling Pathways
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  4. Reference Standards

Reference Standards

Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.

Reference Standards Related Products (11061):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-109068AR
    Parsaclisib hydrochloride (Standard)
    Parsaclisib hydrochloride (Standard) is the analytical standard of Parsaclisib (hydrochloride) (HY-109068A). This product is intended for research and analytical applications. Parsaclisib hydrochloride (INCB050465 hydrochloride) is a potent, selective and orally active inhibitor of PI3Kδ, with an IC50 of 1 nM at 1 mM ATP. Parsaclisib hydrochloride shows approximately 20000-fold selectivity over other PI3K class I isoforms. Parsaclisib hydrochloride can be used for the research of relapsed or refractory B-cell malignancies.
    Parsaclisib hydrochloride (Standard)
  • HY-20046R
    4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene (Standard)
    4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene (Standard)
  • HY-W103960R
    Mirabegron impurity-1 (Standard)
    Mirabegron impurity-1 (Standard) is the analytical standard of Mirabegron impurity-1. This product is intended for research and analytical applications. Mirabegron impurity-1 is a potent and selective β3- adrenergic receptor agonist. Mirabegron impurity-1 has the activity of inhibiting metabolism. Mirabegron impurity-1 can be used in the study of the study of bladder impurity .
    Mirabegron impurity-1 (Standard)
  • HY-103409R
    ABT-724 trihydrochloride (Standard)
    ABT-724 trihydrochloride (Standard) is the analytical standard of ABT-724 trihydrochloride (HY-103409). This product is intended for research and analytical applications. ABT-724 trihydrochloride is a potent and highly selective dopamine D4 receptor agonist with an EC50 of 12.4 nM for human dopamine D4 receptor. ABT-724 trihydrochloride is a potent partial agonist at the rat D4 (EC50 of 14.3 nM) and the ferret D4 receptor (EC50 of 23.2 nM), and has no effect on dopamine D1, D2, D3, or D5 receptors. ABT-724 trihydrochloride could be useful for the treatment of erectile dysfunction and has favorable side-effect profile.
    ABT-724 trihydrochloride (Standard)
  • HY-101029R
    MBM-55 (Standard)
    MBM-55 (Standard) is the analytical standard of MBM-55 (HY-101029). This product is intended for research and analytical applications. MBM-55 is a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 1 nM. MBM-55 shows a 20-fold or greater selectivity in most kinases with the exception of RSK1 (IC50=5.4 nM) and DYRK1a (IC50=6.5 nM). MBM-55 effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis. MBM-55 shows antitumor activities, and no obvious toxicity to mice.
    MBM-55 (Standard)
  • HY-109085R
    Difamilast (Standard)
    Difamilast (Standard) is the analytical standard of Difamilast. This product is intended for research and analytical applications. Difamilast (OPA-15406) is a topical, selective and nonsteroidal phosphodiesterase-4 (PDE4) inhibitor with particularly efficient inhibition of subtype B (IC50=11.2 nM). Difamilast can be used for the research of mild to moderate atopic dermatitis (AD).
    Difamilast (Standard)
  • HY-101105AR
    SB-224289 hydrochloride (Standard)
    SB-224289 (hydrochloride) (Standard) is the analytical standard of SB-224289 (hydrochloride) (HY-101105A). This product is intended for research and analytical applications. SB-224289 hydrochloride is a selective 5-HT1B receptor antagonist, with anxiolytic effect.
    SB-224289 hydrochloride (Standard)
  • HY-17446R
    Icatibant (Standard)
    Icatibant (Standard) is the analytical standard of Icatibant. This product is intended for research and analytical applications. Icatibant (HOE-140) is a potent and specific peptide antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM and 0.798 nM respectively.
    Icatibant (Standard)
  • HY-W017049R
    Sodium trifluoroacetate (Standard)
    Sodium 2,2,2-trifluoroacetate (Standard) is the analytical standard of Sodium 2,2,2-trifluoroacetate. This product is intended for research and analytical applications.
    Sodium trifluoroacetate (Standard)
  • HY-Z16070R
    Hydronopol (Standard)
    Hydronopol (Standard) is the analytical standard of Hydronopol. This product is intended for research and analytical applications.
    Hydronopol (Standard)
  • HY-121776R
    Nicomol (Standard)
    Nicomol (Standard) is the analytical standard of Nicomol. This product is intended for research and analytical applications. Nicomol is an orally active hypolipidemic agent that can increase the high density lipoprotein cholesterol (HDL-C) level. Nicomol inhibits the rapid rise of plasma free fatty acids.
    Nicomol (Standard)
  • HY-Z2765R
    Sitagliptin impurity 4 (Standard)
    (R)-3-((tert-butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic acid (Sitagliptin Impurity） (Standard) is the analytical standard of (R)-3-((tert-butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic acid (Sitagliptin Impurity）. This product is intended for research and analytical applications.
    Sitagliptin impurity 4 (Standard)
  • HY-W101576R
    4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline (Standard)
    4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline (Standard) is the analytical standard of 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline. This product is intended for research and analytical applications.
    4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline (Standard)
  • HY-N1939R
    Icariside I (Standard)
    Icariside I (Standard) is the analytical standard of Icariside I (HY-N1939). This product is intended for research and analytical applications. Icariside I (GH01) is an orally active metabolite of icalin. Icariside I improves estrogen deficiency-induced osteoporosis by simultaneously regulating osteoblast and osteoclast differentiation. Icariside I promotes ATP (HY-B2176) or Nigericin (HY-127019)-induced mtROS production and NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity. Icariside I does not alter the activation of NLRC4 and AIM2 inflammasomes. Icariside I inhibits breast cancer proliferation, apoptosis, invasion, and metastasis by targeting the IL-6/STAT3 pathway. Icariside I is a kynurenine-AhR pathway inhibitor that alleviates cancer by blocking tumor immune escape.
    Icariside I (Standard)
  • HY-Z1906R
    Dabigatran impurity 10 (Standard)
    2-((3-cyanophenyl)amino)acetic acid (Dabigatran Impurity） (Standard) is the analytical standard of 2-((3-cyanophenyl)amino)acetic acid (Dabigatran Impurity）. This product is intended for research and analytical applications.
    Dabigatran impurity 10 (Standard)
  • HY-100007R
    Vonoprazan (Standard)
    Vonoprazan (Standard) is the analytical standard of Vonoprazan. This product is intended for research and analytical applications. Vonoprazan (TAK-438 free base), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan inhibits H+,K+-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease. Vonoprazan can be used for eradication of Helicobacter pylori.
    Vonoprazan (Standard)
  • HY-W141036R
    1-Bromo-2-(bromomethyl)-4,5-dimethoxybenzene (Standard)
    1-Bromo-2-(bromomethyl)-4,5-dimethoxybenzene (Standard)
  • HY-B0536R
    Clinafloxacin (Standard)
    Clinafloxacin (Standard) is the analytical standard of Clinafloxacin. This product is intended for research and analytical applications. Clinafloxacin (AM 1091) is a potent and broad-spectrum fluoroquinolone antibiotic, has inhibitory activity against gram-positive, gram-negative bacterias, and anaerobic pathogens in vitro. Clinafloxacin is against DNA gyrase and topoisomerase IV of S. aureus with IC50 values of 0.92 µg/ml and 1.62 µg/ml, respectively.
    Clinafloxacin (Standard)
  • HY-W001251R
    3,5-Dimethoxybenzoic acid (Standard)
    3,5-Dimethoxybenzoic acid (Standard) is the analytical standard of 3,5-Dimethoxybenzoic acid (HY-W001251). This product is intended for research and analytical applications. 3,5-Dimethoxybenzoic acid is an aromatic organic acid and antifungal agent. 3,5-Dimethoxybenzoic acid can also be used as an intermediate for anticancer agents. 3,5-Dimethoxybenzoic acid can be isolated from the leaves of Melia azedarach. 3,5-Dimethoxybenzoic acid exhibits antifungal activity against A. rabiei with an MIC of 0.125 mg/mL. 3,5-Dimethoxybenzoic acid has anti-wrinkle, anti-inflammatory, antioxidant, and skin regeneration effects.
    3,5-Dimethoxybenzoic acid (Standard)
  • HY-107527R
    Org 25543 hydrochloride (Standard)
    Org 25543 hydrochloride (Standard) is the analytical standard of Org 25543 (hydrochloride) (HY-107527). This product is intended for research and analytical applications. Org 25543 hydrochloride is a selective and irreversible GlyT2 inhibitor (IC50: 16 nM). Org 25543 hydrochloride has analgesia effect. Org 25543 hydrochloride ameliorates mechanical allodynia after partial sciatic nerve ligation injury in mice.
    Org 25543 hydrochloride (Standard)