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Reference Standards
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Reference Standards Related Products (11751)
Related Products (11751)
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Hexanoylglycine (Standard)
0 ImagesCat. No.: HY-113150RCAS No.: 24003-67-6Hexanoylglycine (Standard) is the analytical standard of Hexanoylglycine. This product is intended for research and analytical applications. Hexanoylglycine is an endogenous metabolite present in Urine that can be used for the research of Ethylmalonic Encephalopathy. -
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Nuvisertib (Standard)
0 ImagesSynonyms: TP-3654 (Standard)Nuvisertib (Standard) (TP-3654 (Standard)) is the analytical standard of Nuvisertib (HY-101126). This product is intended for research and analytical applications. Nuvisertib (TP-3654) is an orally active second-generation pan-PIM kinase inhibitor with Ki values of 5 nM, 239 nM, and 42 nM against PIM-1, PIM-2, and PIM-3, respectively. Nuvisertib inhibits JAK-independent inflammatory and survival signaling pathways, reduces the production of proinflammatory cytokines, restores apoptotic sensitivity, inhibits mTORC1, MYC, and TGF-β signaling pathways, and decreases the expression of fibrosis markers. Nuvisertib selectively impairs the transport function of ABCG2, resensitizes multidrug-resistant cancer cells to cytotoxic drugs, and overcomes JAK2 inhibitor resistance. Nuvisertib can be used in research related to myelofibrosis, renal cell carcinoma, multidrug-resistant cancer, advanced solid tumors, urothelial carcinoma, and prostate adenocarcinoma. -
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A-484954 (Standard)
0 ImagesCat. No.: HY-110096RCAS No.: 142557-61-7 -
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α-Thujone (Standard)
0 ImagesCat. No.: HY-121618RCAS No.: 546-80-5α-Thujone (Standard) is the analytical standard of α-Thujone. This product is intended for research and analytical applications. α-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC50 for α-Thujone is 21 μM in suppressing the GABA-induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and easily penetrates the blood-brain barrier. -
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- 2,4-Dihydroxy-5-methoxypyrimidine (Standard)
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RU.521 (Standard)
0 ImagesCat. No.: HY-114180RCAS No.: 2262452-06-0Synonyms: RU320521 (Standard)RU.521 (Standard) is the analytical standard of RU.521 (HY-114180). This product is intended for research and analytical applications. RU.521 (RU320521) is a potent and selective cyclic GMP-AMP synthase (cGAS) inhibitor and inhibits cGAS-mediated interferon upregulation. RU.521 suppresses dsDNA-activated reporter activity with an IC50 of 0.7 μM. RU.521 reduces constitutive expression of interferon in macrophages from a mouse model of Aicardi-Goutières syndrome (AGS). -
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- 3-Chloro-4-fluoronitrobenzene (Standard)
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Micheliolide (Standard)
0 ImagesMicheliolide is a sesquiterpene lactone with anti-cancer and anti-inflammatory effects, which is derived from Michelia compressa and Michelia champaca. Micheliolide can attenuate high glucose-stimulated NF-κB activation, IκBα degradation, and the expression of MCP-1, TGF-β1, and FN in mouse mesangial cells. Micheliolide inhibits LPS (HY-D1056)-induced activation of NF-κB and PI3K/Akt/p70S6K pathways to play an anti-inflammatory role. Micheliolide inhibits dextran sodium sulphate (DSS) (HY-116282)-induced inflammatory intestinal disease, colitis-associated cancer and rheumatic arthritis. -
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Robinin (Standard)
0 ImagesRobinin (Standard) is the analytical standard of Robinin. This product is intended for research and analytical applications. Robinin is a flavonoid that can be extracted from the leaves of purple cowpea, inhibiting TGF-β, TLR4/NF-κB and TLR2-PI3k-AKT signaling pathways. Robinin exerts anti-inflammatory and anti-tumor effects. The combination of Robinin and Methotrexate (HY-14519) reduces inflammation in experimental arthritis, Robinin can decrease the Doxorubicin (HY-15142A) induced cardiac toxicity effect. -
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Buparvaquone (Standard)
0 ImagesBuparvaquone (Standard) is the analytical standard of Buparvaquone. This product is intended for research and analytical applications. Buparvaquone is a hydroxynaphthoquinone antiprotozoal agent related to parvaquone and atovaquone. -
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7-Deazapurine impurity 1 (Standard)
0 ImagesCat. No.: HY-Z0610RCAS No.: 876343-10-14-Chloro-6-iodo-7H-pyrrolo[2,3-d]pyrimidine (Standard) is the analytical standard of 4-Chloro-6-iodo-7H-pyrrolo[2,3-d]pyrimidine. This product is intended for research and analytical applications. -
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A-836339 (Standard)
0 ImagesA-836339 (Standard) is the analytical standard of A-836339. This product is intended for research and analytical applications. -
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HBX 41108 (Standard)
0 ImagesHBX 41108 (Standard) is the analytical standard of HBX 41108 (HY-101666). This product is intended for research and analytical applications. HBX 41108 is an inhibitor of ubiquitin-specific protease 7 (USP7) with an IC50 of 424 nM. HBX 41108 inhibits USP7-mediated p53 deubiquitination to stabilize p53 and inhibits cancer cell growth. BX 41108 can be used in cancer and diabetes research. -
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Orsellinic acid (Standard)
0 ImagesOrsellinic acid (Standard) is an analytical standard of Orsellinic acid (HY-N3126). This product is intended for research and analytical applications. Orsellinic acid is a Benzoic acid (HY-N0216) derivative. Orsellinic acid can be isolated from Chaetomium globosum endophytic on Ephedra fasciculata (Mormon tea). Orsellinic acid blocks PAF-mediated Apoptosis, inhibits caspase-3/7 activation, and PARP cleavage. Orsellinic acid can be used in research of neurons and various tumors (non-small cell lung cancer, breast cancer, neuroblastoma, pancreatic cancer). -
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Ethyl Laurate (Standard)
0 ImagesSynonyms: Ethyl dodecanoate (Standard)Ethyl Laurate (Standard) is the analytical standard of Ethyl Laurate. This product is intended for research and analytical applications. Ethyl Laurate is an organic compound commonly used as a flavoring and food additive. It can be used to make fruit, mint and sweet flavors, and is widely used in some food processing and cosmetic production. In addition, this compound is also used as a reagent and intermediate in some organic synthesis reactions. -
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N,N-Dimethyldodecylamine N-oxide (Standard)
0 ImagesCat. No.: HY-W127785RCAS No.: 1643-20-5Synonyms: N,N-Dimethyldodecan-1-amine oxide (Standard); Dodecyldimethylamine oxide (Standard)N,N-Dimethyldodecylamine N-oxide (Standard) is the analytical standard of N-ethyl-N-oxido-dodecan-1-amine. This product is intended for research and analytical applications. N,N-Dimethyldodecylamine N-oxide is an amine oxide surfactant commonly used as a detergent, emulsifier and wetting agent in various industrial processes, especially in personal care products and household cleaning in the production of agents. N,N-Dimethyldodecylamine N-oxide has unique chemical properties that make it an effective ingredient in many product formulations to help reduce surface tension and enhance cleaning power. -
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(3aR,4R,5R,7S,8S,9R,9aS,12R)-8-Hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-(tosyloxy)acetate (Tiamulin Impurity) (Standard)
0 ImagesCat. No.: HY-Z8760RCAS No.: 31716-01-5(3aR,4R,5R,7S,8S,9R,9aS,12R)-8-Hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-(tosyloxy)acetate (Tiamulin Impurity) (Standard) is the analytical standard of (3aR,4R,5R,7S,8S,9R,9aS,12R)-8-Hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-(tosyloxy)acetate (Tiamulin Impurity). This product is intended for research and analytical applications. -
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o-Toluic acid (Standard)
0 Imageso-Toluic acid (Standard) is the analytical standard of o-Toluic acid. This product is intended for research and analytical applications. o-Toluic acid (2-Methylbenzoic acid) is a benzoic acid substituted by a methyl group at position 2. O-Toluic acid plays a role as a xenobiotic metabolite. -
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PI-103 (Standard)
0 ImagesPI-103 (Standard) is the analytical standard of PI-103. This product is intended for research and analytical applications. PI-103 is a potent PI3K and mTOR inhibitor with IC50s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α, p110β, p110δ, p110γ, mTORC1, and mTORC2. PI-103 also inhibits DNA-PK with an IC50 of 2 nM. PI-103 induces autophagy. -
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Isoprenaline hydrochloride (Standard)
0 ImagesIsoprenaline (hydrochloride) (Standard) is the analytical standard of Isoprenaline (hydrochloride). This product is intended for research and analytical applications. Isoprenaline (Isoproterenol) hydrochloride is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma. -
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