Reference Standards
Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.
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Reference Standards 関連製品 (11756)
関連製品 (11756)
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Naphthalene-2,3-dicarboxaldehyde (Standard)
0 Images別名: 2,3-Naphthalenedicarboxaldehyde (Standard); Naphthalene-2,3-dialdehyde (Standard)Naphthalene-2,3-dicarboxaldehyde (Standard) is the analytical standard for Naphthalene-2,3-dicarboxaldehyde (HY-W016288). This product is for research and analytical applications. Naphthalene-2,3-dicarboxaldehyde (NDA) is an effective inhibitor of Candida albicans aspartate semialdehyde dehydrogenase (ASADH), with a Ki value of 45 μM. Naphthalene-2,3-dicarboxaldehyde targets ASADH in the aspartate biosynthetic pathway of Candida albicans. Naphthalene-2,3-dicarboxaldehyde reacts with primary amines to generate highly fluorescent and stable derivatives. Naphthalene-2,3-dicarboxaldehyde serves as a fungistatic agent and a fluorogenic derivatization reagent. Naphthalene-2,3-Dicarboxaldehyde can be used for the research of candidiasis.
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(-)-Enitociclib (Standard)
0 Images製品番号: HY-103019BRCAS 番号: 1610408-96-2別名: (R)-Enitociclib (Standard); (-)-BAY-1251152 (Standard); (-)-VIP152 (Standard)(-)-Enitociclib (Standard) is the analytical standard of (-)-Enitociclib (HY-103019B). This product is intended for research and analytical applications. (-)-Enitociclib ((R)-Enitociclib) is an enantiomer of Enitociclib (HY-103019E) with an optical rotation of (-). Enitociclib is a selective CDK9 inhibitor and apoptosis inducer. Enitociclib inhibits CDK9 activity and reduces the phosphorylation of Ser2 in the carboxyl-terminal domain (CTD) of RNA polymerase Pol II, thereby downregulating the transcription of key oncogenes such as MYC and MCL1. Enitociclib has anti-proliferative activity targeting MYC+ lymphoma and multiple myeloma (MM) cells, and has synergistic effects with Bortezomib (HY-10227) and Lenalidomide (HY-A0003), and can be used in the research of hematological malignancies.
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Dotriacontane (Standard)
0 ImagesDotriacontane (Standard) is the analytical standard of Dotriacontane. This product is intended for research and analytical applications. Dotriacontane is an alkane substance that can be absorbed and metabolized by photosynthetic organisms. It can be labeled with 14C and used for carbon tracing.
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Pactimibe sulfate (Standard)
0 Images製品番号: HY-100401ARCAS 番号: 608510-47-0別名: CS-505 (Standard)Pactimibe (sulfate) (Standard) is the analytical standard of Pactimibe (sulfate) (HY-100401A). This product is intended for research and analytical applications. Pactimibe sulfate (CS-505) is a dual ACAT1/2 inhibitor with IC50s of 4.9 μM and 3.0 μM, respectively. Pactimibe sulfate (CS-505) inhibits ACAT with IC50s of 2.0 μM, 2.7 μM, 4.7 μM in the liver, macrophages and THP-1 cells, respectively. Pactimibe sulfate (CS-505) noncompetitively inhibits oleoyl-CoA with a Ki value of 5.6 μM. Moreover, Pactimibe sulfate (CS-505) obviously inhibits cholesteryl ester formation with an IC50 of 6.7 μM. Pactimibe sulfate (CS-505) possesses anti-atherosclerotic potential with lowering plasma cholesterol activity.
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Tenuazonic acid (Standard)
0 ImagesTenuazonic acid (Standard) is the analytical standard of Tenuazonic acid. This product is intended for research and analytical applications. Tenuazonic acid is a nonhost-selective mycotoxin belonging to the tetramic acids family. Tenuazonic acid inhibits protein biosynthesis on ribosomes by suppressing the release of new protein. Tenuazonic acid is acutely toxic, and oral LD50 is set between 81-186 mg/kg in rats and mice. Tenuazonic acid blocks electron transport beyond the primary quinone receptor (QA) by interacting with the D1 protein and is a photosystem II (PSII) inhibitor. In addition, Tenuazonic acid has antiviral effects on measles virus, enterovirus, respiratory virus and so on. Tenuazonic acid has an inhibitory effect on skin cancer.
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Mefenamic acid (Standard)
0 ImagesMefenamic acid (Standard) is the analytical standard of Mefenamic acid. This product is intended for research and analytical applications. Mefenamic acid is a BBB-permeable non-steroidal anti-inflammatory agent, acting as a competitive inhibitor of hCOX-1 and hCOX-2, with IC50s of 40 nM and 3 μM for hCOX-1 and hCOX-2, respectively.
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Chloroquine dihydrochloride (Standard)
0 ImagesChloroquine (dihydrochloride) (Standard) is the analytical standard of Chloroquine (dihydrochloride). This product is intended for research and analytical applications. Chloroquine dihydrochloride is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine dihydrochloride is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine dihydrochloride is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC50=1.13 μM)[1][2][3][4].
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PC786 (Standard)
0 Images製品番号: HY-102038RCAS 番号: 1902114-15-1PC786 (Standard) is the analytical standard of PC786 (HY-102038). This product is intended for research and analytical applications. PC786 is an inhaled respiratory syncytial virus (RSV) L protein polymerase inhibitor. PC786 demonstrates potent antiviral activity against RSV-A (IC50 <0.09 to 0.71 nM) and RSV-B (IC50, 1.3 to 50.6 nM).
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Semagacestat (Standard)
0 Images別名: LY450139 (Standard)Semagacestat (Standard) is the analytical standard of Semagacestat. This product is intended for research and analytical applications. Semagacestat is a γ-secretase inhibitor, inhibits β-amyloid (Aβ42), Aβ38 and Aβ40 with IC50s of 10.9, 12 and 12.1 nM, respectively; also inhibits Notch signaling with IC50 of 14.1 nM. Semagacestat can be used for the research of alzheimer's?disease.
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Diisopropyl phthalate (Standard)
0 Images別名: DiPP (Standard)Diisopropyl phthalate (Standard) (DiPP (Standard)) is the analytical standard of Diisopropyl phthalate (HY-W011926). This product is intended for research and analytical applications. Diisopropyl phthalate (DiPP) is a phthalate diester, which is widely used as an additive in plastics and consumer products. Diisopropyl phthalate has a weak binding ability to the recombinant human estrogen receptor, with an IC50 of 41000 μM.
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(+)-Secoisolariciresinol (Standard)
0 Images製品番号: HY-N8172RCAS 番号: 145265-02-7(+)-Secoisolariciresinol (Standard) is the analytical standard of (+)-Secoisolariciresinol. This product is intended for research and analytical applications. (+)-Secoisolariciresinol, a lignan compound, is a (+)-enantiomer of Secoisolariciresinol.
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Olprinone Hydrochloride (Standard)
0 Images別名: Loprinone Hydrochloride (Standard)Olprinone (Loprinone) Hydrochloride Standard is the analytical standard of Olprinone (Hydrochloride) (HY-14254). This product is intended for research and analytical applications. Olprinone (Loprinone) Hydrochloride is a potent and selective phosphodiesterase 3 (PDE3) inhibitor, with IC50 values of 150, 100, 0.35, and 14 μM against PDE1, PDE2, PDE3, and PDE4, respectively. Olprinone Hydrochloride exerts comprehensive protective effects including anti-inflammatory, antioxidant, and anti-apoptotic activities by elevating intracellular cAMP levels and inhibiting the NF-κB and MAPK signaling pathways. Olprinone Hydrochloride can be used in studies related to lung injury, spinal cord injury, heart failure, myocardial ischemia-reperfusion injury, and cerebral ischemic injury.
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MX1013 (Standard)
0 Images製品番号: HY-10397ARCAS 番号: 582316-00-5別名: CV1013 (Standard); Z-VD-FMK (Standard)MX1013 (Standard) is the analytical standard of MX1013 (HY-10397A). This product is intended for research and analytical applications. MX1013 is a potent, irreversible dipeptide caspase inhibitor vith antiapoptotic activity. MX1013 inhibits recombinant human caspase 3 with an IC50 of 30 nM.
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JT010 (Standard)
0 Images製品番号: HY-111132RCAS 番号: 917562-33-5JT010 (Standard) is the analytical standard of JT010 (HY-111132). This product is intended for research and analytical applications. JT010 is a covalent and site-selective TRPA1 agonist. JT010 can be used in myocardial infarction research.
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Ononin (Standard)
0 Images別名: Ononoside (Standard); Formononetin 7-O-β-D-glucopyranoside (Standard)Ononin (Standard) is the analytical standard of Ononin. Ononin is an orally active isoflavone. Ononin inhibits the ERK/JNK/p38 and PI3K/Akt/mTOR pathways. Ononin regulates Apoptosis. Ononin has anti-tumor effects on laryngeal cancer and lung cancer. Ononin has neuroprotective effects. Ononin alleviates endoplasmic reticulum stress and diabetic nephropathy.
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Betamethasone 21-Propionate (Standard)
0 Images製品番号: HY-W740582RCAS 番号: 75883-07-7Betamethasone 21-Propionate (Standard) is the analytical standard of Betamethasone 21-Propionate. This product is intended for research and analytical applications.
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Fostemsavir (Standard)
0 Images別名: BMS-663068 (Standard)Fostemsavir (Standard) is the analytical standard of Fostemsavir. This product is intended for research and analytical applications. Fostemsavir (BMS-663068) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir (BMS-663068) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.
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Lenacapavir (Standard)
0 Images製品番号: HY-111964RCAS 番号: 2189684-44-2別名: GS-6207 (Standard)Lenacapavir (Standard) is the analytical standard of Lenacapavir (HY-111964). This product is intended for research and analytical applications. Lenacapavir (GS-6207) is an HIV-1 capsid inhibitor. Lenacapavir binds to the interface between capsid hexamers and CA monomers, disrupts capsid assembly and viral maturation, inhibits nuclear translocation of HIV-1 DNA, interferes with CA-mediated protein-protein interactions, reduces the formation of 2-LTR circles and pre-integration proviruses, induces aberrant capsids, and decreases the production of mature HIV-1. Lenacapavir exhibits activity against a variety of HIV-1 subtypes and clinical isolates. Lenacapavir is applicable to research related to human immunodeficiency virus type 1 (HIV-1) infection.
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Ofurace (Standard)
0 Images製品番号: HY-122451RCAS 番号: 58810-48-3別名: Milfuram (Standard); RE 20615 (Standard)Ofurace (Standard) is the analytical standard of Ofurace. This product is intended for research and analytical applications. Ofurace is a fungicide that is extremely active against Pythium ultima, Phytophthora tabacum and Phytophthora palmi. Ofurace has a greater effect on sporangia formation than on mycelium growth.
