Transmembrane Glycoprotein
Transmembrane Glycoprotein
Transmembrane glycoproteins are important components of cell membranes and are characterized by oligosaccharide chains covalently linked to polypeptide chains. Glycosylation sites are mainly located in their extracellular regions, achieved by N-linked glycosylation (linked to asparagine residues) or O-linked glycosylation (linked to serine or threonine residues). Sugar chains not only provide structural stability to proteins but also confer functional specificity. Many transmembrane glycoproteins are receptors, such as G protein-coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs). Most （clusters of differentiation）CD molecules are also transmembrane glycoproteins expressed on the surface of antigen-presenting cells[1][2].
References:
- [1]. L Franco, et al. The transmembrane glycoprotein CD38 is a catalytically active transporter responsible for generation and influx of the second messenger cyclic ADP-ribose across membranes. FASEB J. 1998 Nov;12(14):1507-20. [Content Brief]
- [2]. Kumi Oshima, et al. SHPS-1, a multifunctional transmembrane glycoprotein. FEBS Lett. 2002 May 22;519(1-3):1-7. [Content Brief]
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Transmembrane Glycoprotein Inhibitors
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Transmembrane Glycoprotein Agonists
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Transmembrane Glycoprotein Antagonists
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Transmembrane Glycoprotein Activators
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Transmembrane Glycoprotein Modulators
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Transmembrane Glycoprotein Ligands
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Transmembrane Glycoprotein Related Products (380)
Related Products (380)
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PY265
0 ImagesCat. No.: HY-P991732
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AGS-67E
0 ImagesCat. No.: HY-P990317Purity: 99.46%
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Anti-EFNA4 Antibody
0 ImagesCat. No.: HY-P991109Purity: 99.60%Synonyms: PF-06647263 antibody
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Anti-Mouse CD317/BST2 Antibody (927)
0 ImagesCat. No.: HY-P990276Anti-Mouse CD317/BST2 Antibody (927) is a rat-derived IgG2b κ type antibody inhibitor, targeting to mouse CD317/BST2. Anti-Mouse CD317/BST2 Antibody (927) can deplete plasmacytoid dendritic cells (pDC). Anti-Mouse CD317/BST2 Antibody (927) can be used for the researches of cancer, infection, inflammation and immunology, such as head and neck squamous cell carcinoma (HNSCC), murine cytomegalovirus (MCMV) infection and asthma.
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Anti-Mouse Thy1.1/CD90.1 Antibody (19E12)
0 ImagesCat. No.: HY-P990156Anti-Mouse Thy1.1/CD90.1 Antibody (19E12) is an anti-mouse Thy1.1/CD90.1 IgG2a monoclonal antibody. Anti-Mouse Thy1.1/CD90.1 Antibody (19E12) can deplete CD90.1+ cells. Anti-Mouse Thy1.1/CD90.1 Antibody (19E12) can clear Tregs. Anti-Mouse Thy1.1/CD90.1 Antibody (19E12) can be used for researches on inflammation conditions and immune response such as airway inflammation and experimental autoimmune encephalomyelitis (EAE).
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Anti-Tenascin C Antibody
0 ImagesCat. No.: HY-P991470Synonyms: Neuradiab antibodyAnti-Tenascin C Antibody (Neuradiab antibody) is a human monoclonal antibody (mAb) targeting Tenascin C. Anti-Tenascin C Antibody can be used in Glioblastoma research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001).
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1-(4-Methoxyphenyl)-3-methyl-1H-pyrazol-5(4H)-one
0 Images1-(4-Methoxyphenyl)-3-methyl-1H-pyrazol-5(4H)-one (Compound 2) has antiprion activity in ScN2a and F3 cells with IC50 values of 13 nM and 25 nM, respectively.
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Leukotuximab
0 ImagesCat. No.: HY-P992058Purity: 99.9%Synonyms: ART-140; DNP-001; EGX-040Leukotuximab (ART-140; EGX-040) is an anti-JL1 mAb and an anti-leukemic agent. Leukotuximab targets the JL1 epitope of CD43 and exerts cytotoxic effects on JL1-positive leukemia cells. Except for thymocytes and some bone marrow mononuclear cells, Leukotuximab causes no damage to most normal tissues. Leukotuximab can be used in the research of acute myeloid leukemia, acute lymphoblastic leukemia, and myelodysplastic syndrome.
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Anti-Mouse CD83 Antibody (Michel-17)
0 ImagesCat. No.: HY-P990261Purity: 98.722%Anti-Mouse CD83 Antibody (Michel-17) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse CD83. Anti-Mouse CD83 Antibody (Michel-17) can block CD83 and inhibit T cells proliferation. Anti-Mouse CD83 Antibody (Michel-17) can be used for the researches of cancer and immunology, such as solid tumor.
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Anti-Mouse ICOSL/CD275 Antibody (HK5.3)
0 ImagesCat. No.: HY-P990123Purity: 98.59%Anti-Mouse ICOSL/CD275 Antibody (HK5.3) is an anti-mouse ICOSL/CD275 IgG2a monoclonal antibody. Anti-Mouse ICOSL/CD275 Antibody (HK5.3) can inhibit the adhesion between T cells and endothelial cells. Anti-Mouse ICOSL/CD275 Antibody (HK5.3) can reduce the expansion of tissue resident (TR) Treg cells. Anti-Mouse ICOSL/CD275 Antibody (HK5.3) can be used for researches on inflammation and infection conditions such as influenza virus infection and arthritis.
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Arcitumomab
0 ImagesCat. No.: HY-P9937CAS No.: 154361-48-5Synonyms: IMMU-4Arcitumomab is a murine anti-carcinoembryonic antigen (CEA) monoclonal antibody Fab’ fragment. Arcitumomab can be labeled with technetium-99m and can be used for single-photon emission computed tomography (SPECT) imaging.
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Biotinyl-neuropeptide W-23 (human)
0 ImagesBiotinyl-neuropeptide W-23 (human) is a biotinylated Neuropeptide W-23 (human) (HY-P1035). Neuropeptide W-23 (human) is an agonist of NPBW1 (GPR7) and NPBW2 (GPR8).
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Nilvanstomig
0 ImagesCat. No.: HY-P992121CAS No.: 3061475-22-4Synonyms: ZG005Nilvanstomig (ZG005) is an antibody targeting PD-1 and TIGIT. Nilvanstomig blocks the PD-1/TIGIT pathway, thereby promoting the synergistic activation of T cells and enhancing the anti-tumor activity of NK cells. Nilvanstomig is applicable to relevant research on advanced cervical cancer.
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Lancastotug
0 ImagesCat. No.: HY-P990746CAS No.: 2768355-20-8Synonyms: AK-127
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VCAM1 binding peptide acetate
0 ImagesCat. No.: HY-P11088APurity: 99.76%VCAM1 binding peptide acetate is a VCAM1 binder with internalization activity. VCAM1 binding peptide acetate can be labeled with 5-FAM. VCAM1 binding peptide acetate serves as a component of biosensing systems for visualizing in vitro VCAM1 endocytic pathways. VCAM1 binding peptide acetate forms the research and development basis for MacroP and NAMP, PET radiotracers targeting VCAM1. VCAM1 binding peptide acetate is applicable to studies related to atherosclerosis.
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EP9
0 ImagesCat. No.: HY-P11797Purity: 99.84%EP9 is a peptide targeting CD63. EP9 binds specifically to the extracellular region of CD63, including a groove in the large extracellular loop (EC2) or the extracellular end of CD63’s central cavity, triggering endocytosis of decorated nanoemulsions/liposomes into cells. EP9 promotes cellular uptake of decorated nanoemulsions/liposomes into activated cardiac fibroblasts and epicardial stromal cells via caveolae and/or clathrin-coated pits. EP9 can be used for the research of myocardial infarction, cardiac fibrosis.
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hu3S193
0 ImagesCat. No.: HY-P991458hu3S193 is a human IgG monoclonal antibody (mAb) targeting Lewis Y. hu3S193 has excellent immune effector function (complement-dependent cytotoxicity) (IC50: 1.0 μg/ml) and antibody-dependent cellular cytotoxicity (IC50: 5.0 μg/ml). hu3S193 can be used in small cell lung cancer (SCLC) research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001).
