A1B11
A1B11 is a selective SIRT inhibitor (SIRT2:IC50=5.3 μM) that can be used in the study of neurodegenerative diseases.
For research use only. We do not sell to patients.
- CAS No.: 1602731-56-5
- Formula: C22H25N5O
- Molecular Weight:375.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
SIRT2 5.3 μM (IC50) |
Chemical Information
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CAS No. 1602731-56-5
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Molecular Weight 375.47
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Formula C22H25N5O
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SMILES
O=C(C1=CC=CC=C1NC2=CC=CC(C3=CN(N=N3)CCC4CCCC4)=C2)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)