Antiparasitic agent-32
Antiparasitic agent-32 (compound M9), a Piperaquine (HY-B1896) analog, is a potent P. falciparum lactate dehydrogenase (Pf LDH)-targeting antiparasitic agent (Pf3D7 IC50 = 0.40 μM). Antiparasitic agent-32 exhibits significant activity against both Pf asexual and gametocyte stages. Antiparasitic agent-32 exerts antiplasmodial activity through stable and specific noncovalent interactions at the NADH-binding site. Antiparasitic agent-32 can be used for malaria research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C22H25ClF3N7
- Molecular Weight:479.93
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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P. falciparum 3D7 0.40 μM (IC50) |
Chemical Information
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Molecular Weight 479.93
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Formel C22H25ClF3N7
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SMILES
ClC1C=C2N=CC=C(NCCCCCCNC3=CC(C)=NC4=NC(C(F)(F)F)=NN34)C2=CC1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)