2. Anti-infection Metabolic Enzyme/Protease
  3. Parasite Lactate Dehydrogenase
  4. Antiparasitic agent-32

Antiparasitic agent-32 (compound M9), a Piperaquine (HY-B1896) analog, is a potent P. falciparum lactate dehydrogenase (Pf LDH)-targeting antiparasitic agent (Pf3D7 IC50 = 0.40 μM). Antiparasitic agent-32 exhibits significant activity against both Pf asexual and gametocyte stages. Antiparasitic agent-32 exerts antiplasmodial activity through stable and specific noncovalent interactions at the NADH-binding site. Antiparasitic agent-32 can be used for malaria research.

For research use only. We do not sell to patients.

Antiparasitic agent-32

Antiparasitic agent-32 Chemical Structure

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Antiparasitic agent-32 Related Antibodies

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Description

Antiparasitic agent-32 (compound M9), a Piperaquine (HY-B1896) analog, is a potent P. falciparum lactate dehydrogenase (Pf LDH)-targeting antiparasitic agent (Pf3D7 IC50 = 0.40 μM). Antiparasitic agent-32 exhibits significant activity against both Pf asexual and gametocyte stages. Antiparasitic agent-32 exerts antiplasmodial activity through stable and specific noncovalent interactions at the NADH-binding site. Antiparasitic agent-32 can be used for malaria research[1].

IC50 & Target[1]

P. falciparum 3D7

0.40 μM (IC50)

Molecular Weight

479.93

Formula

C22H25ClF3N7
SMILES

ClC1C=C2N=CC=C(NCCCCCCNC3=CC(C)=NC4=NC(C(F)(F)F)=NN34)C2=CC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antiparasitic agent-32 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antiparasitic agent-32Antiparasitic agent32Antiparasitic agent 32ParasiteLactate DehydrogenaseLDHPiperaquineP. falciparum lactate dehydrogenaseantiplasmodial activitymalariaInhibitorinhibitorinhibit

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