Antiparasitic agent-32
Antiparasitic agent-32 (compound M9), a Piperaquine (HY-B1896) analog, is a potent P. falciparum lactate dehydrogenase (Pf LDH)-targeting antiparasitic agent (Pf3D7 IC50 = 0.40 μM). Antiparasitic agent-32 exhibits significant activity against both Pf asexual and gametocyte stages. Antiparasitic agent-32 exerts antiplasmodial activity through stable and specific noncovalent interactions at the NADH-binding site. Antiparasitic agent-32 can be used for malaria research.
For research use only. We do not sell to patients.
- Formula: C22H25ClF3N7
- Molecular Weight:479.93
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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P. falciparum 3D7 0.40 μM (IC50) |
Chemical Information
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Molecular Weight 479.93
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Formula C22H25ClF3N7
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SMILES
ClC1C=C2N=CC=C(NCCCCCCNC3=CC(C)=NC4=NC(C(F)(F)F)=NN34)C2=CC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antiparasitic agent-32 Related Classifications
HY-180110 Related Classifications
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