AD-9308

AD-9308 is a highly selective and orally active ALDH2 activator. AD-9308 activates ALDH2 to promote the clearance of 4-HNE, inhibiting myocardial fibrosis, inflammation and cell apoptosis. AD-9308 improves mitochondrial function, sarcoplasmic reticulum/ endoplasmic reticulum calcium transport and regulates autophagy, restoring intracellular homeostasis. AD-9308 improves the diastolic and systolic function of the heart in diabetic mice and reverses ventricular mal-reconstruction. AD-9308 can be used for the study of diabetic cardiomyopathy.

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  • CAS. Nr.: 1804942-56-0
  • Formel: C30H36FN3O5
  • Molecular Weight:537.62
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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Alle Aldehyde Dehydrogenase (ALDH) Isoform-spezifische Produkte anzeigen

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