D-01
D-01 is a dual-targeting inhibitor of HIF-1α and EZH2 (IC50: 4.86 μM and 0.99 μM respectively). D-01 inhibits the expression of H3K27me3 protein. D-01 inhibits the migration, clone and the invasion of A549 cells, and also inhibits tube formation of HUVECs. D-01 can be used for research of lung cancer.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C37H43N3O8
- Molecular Weight:657.75
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
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EZH2 0.99 μM (IC50) |
HIF-1α 4.86 μM (IC50) |
Chemical Information
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Molecular Weight 657.75
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Formel C37H43N3O8
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SMILES
CC1(C)OC2=CC=C(C(/C=C/C3=CC=C(OCCCN4CCOCC4)C(OCC(NCC5=C(C)C=C(C)NC5=O)=O)=C3)=O)C(O)=C2C=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
D-01 Related Classifications
HY-162601 Related Classifications
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