SMAD3 - SMAD family member 3 Gene

Also Known as LDS3; mad3; LDS1C; MADH3; JV15-2; hMAD-3; hSMAD3; HSPC193; HsT17436

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 4088

About SMAD3

Cytogenetic location: 15q22.33 Genomic coordinates (GRCh38): 15:67,065,602-67,195,169 (from NCBI)

This gene has 18 transcripts (splice variants), 277 orthologues, 7 paralogues and is associated with 96 phenotypes. Ubiquitous expression in urinary bladder (RPKM 13.6), ovary (RPKM 13.1) and 25 other tissues.

Summary

The Smad Family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. The SMAD3 protein functions in the transforming growth factor-beta signaling pathway, and transmits signals from the cell surface to the nucleus, regulating gene activity and cell proliferation. This protein forms a complex with Other SMAD proteins and binds DNA, functioning both as a transcription factor and tumor suppressor. Mutations in this gene are associated with aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3. [provided by RefSeq, May 2022]

SMAD3 Products (11)

mRNA Protein Name
NM_001145102.2 NP_001138574.1 mothers against decapentaplegic homolog 3 isoform 2
NM_001145103.2 NP_001138575.1 mothers against decapentaplegic homolog 3 isoform 3
NM_001145104.2 NP_001138576.1 mothers against decapentaplegic homolog 3 isoform 4
NM_001407011.1 NP_001393940.1 mothers against decapentaplegic homolog 3 isoform 5
NM_001407012.1 NP_001393941.1 mothers against decapentaplegic homolog 3 isoform 6
NM_001407013.1 NP_001393942.1 mothers against decapentaplegic homolog 3 isoform 7
NM_001407014.1 NP_001393943.1 mothers against decapentaplegic homolog 3 isoform 8
NM_001407015.1 NP_001393944.1 mothers against decapentaplegic homolog 3 isoform 9
NM_001407016.1 NP_001393945.1 mothers against decapentaplegic homolog 3 isoform 2
NM_001407017.1 NP_001393946.1 mothers against decapentaplegic homolog 3 isoform 4
NM_005902.4 NP_005893.1 mothers against decapentaplegic homolog 3 isoform 1
Molecular Function GO Annotation Evidence Verweise Source
enables DEAD/H-box RNA helicase binding IPI
IPI: Inferred from physical interaction
18548003 GOA
enables DNA binding IDA
IDA: Inferred from direct assay
28467929 GOA
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
24378993 GOA
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
24378993 GOA
contributes to DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
9111321 GOA
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
9732876 GOA
enables DNA-binding transcription factor activity IMP
IMP: Inferred from mutant phenotype
32141990 GOA
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
21947082 GOA
enables DNA-binding transcription factor binding IPI
IPI: Inferred from physical interaction
21828274 GOA
enables DNA-binding transcription repressor activity IDA
IDA: Inferred from direct assay
28467929 GOA
enables R-SMAD binding IPI
IPI: Inferred from physical interaction
9311995 GOA
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
18832382 GOA
enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
IPI: Inferred from physical interaction
9732876 GOA
enables bHLH transcription factor binding IPI
IPI: Inferred from physical interaction
21828274 GOA
enables cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
21947082 GOA
enables cis-regulatory region sequence-specific DNA binding IMP
IMP: Inferred from mutant phenotype
32141990 GOA
enables co-SMAD binding IPI
IPI: Inferred from physical interaction
8774881 GOA
enables identical protein binding IPI
IPI: Inferred from physical interaction
18729074 GOA
enables nuclear glucocorticoid receptor binding IPI
IPI: Inferred from physical interaction
12902338 GOA
enables nuclear mineralocorticoid receptor binding IPI
IPI: Inferred from physical interaction
12902338 GOA
enables nuclear receptor binding IPI
IPI: Inferred from physical interaction
31023188 GOA
enables phosphatase binding IPI
IPI: Inferred from physical interaction
16751101 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
9865696 GOA
enables protein homodimerization activity IPI
IPI: Inferred from physical interaction
8774881 GOA
enables protein kinase binding IPI
IPI: Inferred from physical interaction
12874272 GOA
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
10823886 GOA
enables sterol response element binding IGI
IGI: Inferred from genetic interaction
25605017 GOA
enables transcription cis-regulatory region binding IDA
IDA: Inferred from direct assay
9732876 GOA
enables transcription coactivator binding IPI
IPI: Inferred from physical interaction
16777850 GOA
enables transcription corepressor binding IPI
IPI: Inferred from physical interaction
14612439 GOA
enables transforming growth factor beta receptor binding IPI
IPI: Inferred from physical interaction
9311995 GOA
enables ubiquitin binding IDA
IDA: Inferred from direct assay
18794808 GOA
enables ubiquitin protein ligase binding IPI
IPI: Inferred from physical interaction
11278251 GOA
enables zinc ion binding IDA
IDA: Inferred from direct assay
12686552 GOA
Biological Process GO Annotation Evidence Verweise Source
involved in SMAD protein signal transduction IDA
IDA: Inferred from direct assay
9111321 GOA
acts upstream of SMAD protein signal transduction IMP
IMP: Inferred from mutant phenotype
30729664 GOA
involved in activation of cysteine-type endopeptidase activity involved in apoptotic process IMP
IMP: Inferred from mutant phenotype
15107418 GOA
involved in activin receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
15150278 GOA
involved in cell-cell junction organization IMP
IMP: Inferred from mutant phenotype
18505915 GOA
involved in cellular response to transforming growth factor beta stimulus IDA
IDA: Inferred from direct assay
12902338 GOA
involved in extrinsic apoptotic signaling pathway IMP
IMP: Inferred from mutant phenotype
15334054 GOA
involved in immune response IMP
IMP: Inferred from mutant phenotype
16886151 GOA
involved in negative regulation of cell growth IDA
IDA: Inferred from direct assay
8774881 GOA
involved in negative regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
14555988 GOA
involved in negative regulation of cytosolic calcium ion concentration IDA
IDA: Inferred from direct assay
27038547 GOA
involved in negative regulation of fat cell differentiation IDA
IDA: Inferred from direct assay
19816956 GOA
acts upstream of negative regulation of gene expression IMP
IMP: Inferred from mutant phenotype
24378993 GOA
involved in negative regulation of miRNA transcription IMP
IMP: Inferred from mutant phenotype
32141990 GOA
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
8774881 GOA
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
14555988 GOA
involved in nodal signaling pathway IMP
IMP: Inferred from mutant phenotype
15150278 GOA
involved in positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
9111321 GOA
involved in positive regulation of epithelial to mesenchymal transition IDA
IDA: Inferred from direct assay
21307346 GOA
involved in positive regulation of epithelial to mesenchymal transition IMP
IMP: Inferred from mutant phenotype
18505915 GOA
involved in positive regulation of extracellular matrix assembly IDA
IDA: Inferred from direct assay
21307346 GOA
acts upstream of positive regulation of extracellular matrix assembly IMP
IMP: Inferred from mutant phenotype
30729664 GOA
involved in positive regulation of gene expression IDA
IDA: Inferred from direct assay
21307346 GOA
involved in positive regulation of miRNA transcription IDA
IDA: Inferred from direct assay
24378993 GOA
acts upstream of positive regulation of miRNA transcription IMP
IMP: Inferred from mutant phenotype
30729664 GOA
involved in positive regulation of miRNA transcription IMP
IMP: Inferred from mutant phenotype
24378993 GOA
involved in positive regulation of nitric oxide biosynthetic process IDA
IDA: Inferred from direct assay
27038547 GOA
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
8774881 GOA
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
14555988 GOA
involved in regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
25060702 GOA
involved in regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
21947082 GOA
involved in regulation of transforming growth factor beta2 production IMP
IMP: Inferred from mutant phenotype
12411310 GOA
acts upstream of response to angiotensin IMP
IMP: Inferred from mutant phenotype
30729664 GOA
involved in response to hypoxia IMP
IMP: Inferred from mutant phenotype
12411310 GOA
involved in transforming growth factor beta receptor signaling pathway IDA
IDA: Inferred from direct assay
9311995 GOA
involved in transforming growth factor beta receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
8774881 GOA
Cellular Component GO Annotation Evidence Verweise Source
part of SMAD protein complex IDA
IDA: Inferred from direct assay
18832382 GOA
located in chromatin IDA
IDA: Inferred from direct assay
21828274 GOA
located in cytoplasm IDA
IDA: Inferred from direct assay
9311995 GOA
located in cytosol IGI
IGI: Inferred from genetic interaction
23723426 GOA
part of heteromeric SMAD protein complex IDA
IDA: Inferred from direct assay
21828274 GOA
located in nuclear inner membrane IDA
IDA: Inferred from direct assay
15647271 GOA
located in nucleus IDA
IDA: Inferred from direct assay
9311995 GOA
located in nucleus IGI
IGI: Inferred from genetic interaction
23723426 GOA
part of receptor complex IMP
IMP: Inferred from mutant phenotype
8774881 GOA
part of transcription regulator complex IDA
IDA: Inferred from direct assay
21947082 GOA
part of transcription regulator complex IPI
IPI: Inferred from physical interaction
25060702 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SMAD3 Protein Structure

MH1

MH1: MH1 domain (31 - 131)

MH2

MH2: MH2 domain (227 - 402)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 425 a.a.
Protein Preferred Names Protein Names

mothers against decapentaplegic homolog 3

  • MAD homolog 3

SMAD3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
SMAD3 P84022 ZNF774 Homo sapiens Q6NX45 32296183
Intra
SMAD3 P84022 ZNF774 Homo sapiens Q6NX45 32296183
Intra
SMAD3 P84022 ZNF774 Homo sapiens Q6NX45 32296183
Intra
SMAD3 P84022 SMAD2 Homo sapiens Q15796 33961781
Intra
SMAD3 P84022 MTMR4 Homo sapiens Q9NYA4 20061380
Intra
SMAD3 P84022 JPH3 Homo sapiens Q8WXH2 32814053
Intra
SMAD3 P84022 JPH3 Homo sapiens Q8WXH2 32814053
Intra
SMAD3 P84022 JPH3 Homo sapiens Q8WXH2 32814053
Intra
SMAD3 P84022 CPSF7 Homo sapiens Q8N684-3 25910212
Intra
SMAD3 P84022 CPSF7 Homo sapiens Q8N684-3 25910212
Intra
SMAD3 P84022 CPSF7 Homo sapiens Q8N684-3 25910212
Intra
SMAD3 P84022 PHC2 Homo sapiens Q8IXK0-5 25910212
Intra
SMAD3 P84022 PHC2 Homo sapiens Q8IXK0-5 25910212
Intra
SMAD3 P84022 PHC2 Homo sapiens Q8IXK0-5 25910212
Intra
SMAD3 P84022 DAB2 Homo sapiens P98082 11387212
Intra
SMAD3 P84022 TLE5 Homo sapiens Q08117-2 25910212
Intra
SMAD3 P84022 TLE5 Homo sapiens Q08117-2 25910212
Intra
SMAD3 P84022 TLE5 Homo sapiens Q08117-2 25910212
Intra
SMAD3 P84022 NEDD4 Homo sapiens P46934-3 32296183
Intra
SMAD3 P84022 NEDD4 Homo sapiens P46934-3 32296183
Intra
SMAD3 P84022 CASP1 Homo sapiens P29466-3 32814053
Intra
SMAD3 P84022 CASP1 Homo sapiens P29466-3 32814053
Intra
SMAD3 P84022 CASP1 Homo sapiens P29466-3 32814053
Intra
SMAD3 P84022 CAMK2A Homo sapiens Q9UQM7 32814053
Intra
SMAD3 P84022 CAMK2A Homo sapiens Q9UQM7 32814053
Intra
SMAD3 P84022 CAMK2A Homo sapiens Q9UQM7 32814053
Intra
SMAD3 P84022 FOXO3 Homo sapiens O43524 21532621
Intra
SMAD3 P84022 FOXH1 Homo sapiens O75593 21828274
Intra
SMAD3 P84022 FLI1 Homo sapiens Q01543 20211142
Intra
SMAD3 P84022 BLZF1 Homo sapiens Q9H2G9 25910212
Intra
SMAD3 P84022 BLZF1 Homo sapiens Q9H2G9 25910212
Intra
SMAD3 P84022 BLZF1 Homo sapiens Q9H2G9 25416956
Intra
SMAD3 P84022 BLZF1 Homo sapiens Q9H2G9 32296183
Intra
SMAD3 P84022 BLZF1 Homo sapiens Q9H2G9 25910212
Intra
SMAD3 P84022 BLZF1 Homo sapiens Q9H2G9 32296183
Intra
SMAD3 P84022 BLZF1 Homo sapiens Q9H2G9 32296183
Intra
SMAD3 P84022 APLP2 Homo sapiens Q06481-5 32814053
Intra
SMAD3 P84022 APLP2 Homo sapiens Q06481-5 32814053
Intra
SMAD3 P84022 APLP2 Homo sapiens Q06481-5 32814053
Intra
SMAD3 P84022 DOCK9 Homo sapiens Q9BZ29 18729074
Intra
SMAD3 P84022 ZFYVE9 Homo sapiens O95405 12154125
Intra
SMAD3 P84022 ZFYVE9 Homo sapiens O95405 31515488
Intra
SMAD3 P84022 ZFYVE9 Homo sapiens O95405 33961781
Intra
SMAD3 P84022 USP7 Homo sapiens Q93009
Y2H
21988832
Intra
SMAD3 P84022 USP7 Homo sapiens Q93009
TAP
18729074
Intra
SMAD3 P84022 SQSTM1 Homo sapiens Q13501
Y2H
21988832
Intra
SMAD3 P84022 SQSTM1 Homo sapiens Q13501 21988832
Intra
SMAD3 P84022 SMAD4 Homo sapiens Q13485 21597466
Intra
SMAD3 P84022 SMAD4 Homo sapiens Q13485
Y2H
25502805
Intra
SMAD3 P84022 SMAD4 Homo sapiens Q13485
PLA
22442258
Intra
SMAD3 P84022 SMAD4 Homo sapiens Q13485 21297662
Intra
SMAD3 P84022 SMAD4 Homo sapiens Q13485 29892012
Intra
SMAD3 P84022 SMAD4 Homo sapiens Q13485 20211142
Intra
SMAD3 P84022 SMAD4 Homo sapiens Q13485
Y2H
21988832
Intra
SMAD3 P84022 SMAD4 Homo sapiens Q13485
Y2H
15231748
Intra
SMAD3 P84022 SMAD4 Homo sapiens Q13485 25910212
Intra
SMAD3 P84022 SMAD4 Homo sapiens Q13485 27107012
Intra
SMAD3 P84022 SMAD4 Homo sapiens Q13485 18729074
Intra
SMAD3 P84022 SMAD4 Homo sapiens Q13485 31515488
Intra
SMAD3 P84022 SMAD4 Homo sapiens Q13485 25910212
Intra
SMAD3 P84022 SMAD4 Homo sapiens Q13485 27107012
Intra
SMAD3 P84022 SMAD4 Homo sapiens Q13485 25910212
Intra
SMAD3 P84022 SMAD4 Homo sapiens Q13485 15350224
Intra
SMAD3 P84022 SMAD4 Homo sapiens Q13485 19135894
Intra
SMAD3 P84022 SMAD4 Homo sapiens Q13485
TAP
18729074
Intra
SMAD3 P84022 SMAD4 Homo sapiens Q13485 29997244
Intra
SMAD3 P84022 SMAD4 Homo sapiens Q13485
Y2H
27107012
Intra
SMAD3 P84022 SMAD4 Homo sapiens Q13485 22045334
Intra
SMAD3 P84022 SMAD4 Homo sapiens Q13485 25502805
Intra
SMAD3 P84022 SKI Homo sapiens P12755 12857746
Intra
SMAD3 P84022 DDX5 Homo sapiens P17844 18548003
Intra
SMAD3 P84022 IPO8 Homo sapiens O15397 17785517
Intra
SMAD3 P84022 SMURF2 Homo sapiens Q9HAU4 32296183
Intra
SMAD3 P84022 SMURF2 Homo sapiens Q9HAU4 32296183
Intra
SMAD3 P84022 SMURF2 Homo sapiens Q9HAU4 22045334
Intra
SMAD3 P84022 SMURF2 Homo sapiens Q9HAU4
TAP
18729074
Intra
SMAD3 P84022 SMURF2 Homo sapiens Q9HAU4 32296183
Intra
SMAD3 P84022 SMURF2 Homo sapiens Q9HAU4
ITC
22045334
Intra
SMAD3 P84022 HIF1A Homo sapiens Q16665 28471448
Intra
SMAD3 P84022 MYD88 Homo sapiens Q99836 21988832
Intra
SMAD3 P84022 MYD88 Homo sapiens Q99836 21988832
Intra
SMAD3 P84022 MYD88 Homo sapiens Q99836
Y2H
21988832
Intra
SMAD3 P84022 PRKACA Homo sapiens P17612 32814053
Intra
SMAD3 P84022 PRKACA Homo sapiens P17612 32814053
Intra
SMAD3 P84022 PRKACA Homo sapiens P17612 32814053
Intra
SMAD3 P84022 SNW1 Homo sapiens Q13573 11278756
Intra
SMAD3 P84022 SNW1 Homo sapiens Q13573
TAP
18729074
Intra
SMAD3 P84022 FAM90A1 Homo sapiens Q86YD7 32296183
Intra
SMAD3 P84022 PHC2 Homo sapiens Q8IXK0 25416956
Intra
SMAD3 P84022 TGIF1 Homo sapiens Q15583 32814053
Intra
SMAD3 P84022 TGIF1 Homo sapiens Q15583 32814053
Intra
SMAD3 P84022 TGIF1 Homo sapiens Q15583 32814053
Intra
SMAD3 P84022 TLE5 Homo sapiens Q08117 25416956
Intra
SMAD3 P84022 PPP1R12C Homo sapiens Q9BZL4
Y2H
21988832
Intra
SMAD3 P84022 CCDC33 Homo sapiens Q8N5R6 25910212
Intra
SMAD3 P84022 CCDC33 Homo sapiens Q8N5R6 25910212
Intra
SMAD3 P84022 CCDC33 Homo sapiens Q8N5R6 25910212
Intra
SMAD3 P84022 WWP1 Homo sapiens Q9H0M0 25910212
Intra
SMAD3 P84022 WWP1 Homo sapiens Q9H0M0 25416956
Intra
SMAD3 P84022 WWP1 Homo sapiens Q9H0M0 32296183
Intra
SMAD3 P84022 WWP1 Homo sapiens Q9H0M0 32296183
Intra
SMAD3 P84022 WWP1 Homo sapiens Q9H0M0 32296183
Intra
SMAD3 P84022 WWP1 Homo sapiens Q9H0M0 25910212
Intra
SMAD3 P84022 WWP1 Homo sapiens Q9H0M0 25910212
Intra
SMAD3 P84022 WWP2 Homo sapiens O00308
TAP
18729074
Intra
SMAD3 P84022 WWP2 Homo sapiens O00308 25910212
Intra
SMAD3 P84022 WWP2 Homo sapiens O00308 25910212
Intra
SMAD3 P84022 WWP2 Homo sapiens O00308 25910212
Intra
SMAD3 P84022 WWP2 Homo sapiens O00308 21258410
Intra
SMAD3 P84022 CPSF7 Homo sapiens Q8N684 25416956
Intra
SMAD3 P84022 CRX Homo sapiens O43186 25910212
Intra
SMAD3 P84022 CRX Homo sapiens O43186 25910212
Intra
SMAD3 P84022 CRX Homo sapiens O43186 25910212
Intra
SMAD3 P84022 MEOX2 Homo sapiens P50222 25910212
Intra
SMAD3 P84022 MEOX2 Homo sapiens P50222 25416956
Intra
SMAD3 P84022 MEOX2 Homo sapiens P50222 25910212
Intra
SMAD3 P84022 MEOX2 Homo sapiens P50222 25416956
Intra
SMAD3 P84022 MEOX2 Homo sapiens P50222 25910212
Intra
SMAD3 P84022 MEOX2 Homo sapiens P50222 25416956
Intra
SMAD3 P84022 TEKT4 Homo sapiens Q8WW24 25416956
Intra
SMAD3 P84022 TEKT4 Homo sapiens Q8WW24 25416956
Intra
SMAD3 P84022 CSNK1D Homo sapiens P48730-2 32814053
Intra
SMAD3 P84022 CSNK1D Homo sapiens P48730-2 32814053
Intra
SMAD3 P84022 CSNK1D Homo sapiens P48730-2 32814053
Intra
SMAD3 P84022 PIK3R1 Homo sapiens P27986-2 32814053
Intra
SMAD3 P84022 PIK3R1 Homo sapiens P27986-2 32814053
Intra
SMAD3 P84022 PIK3R1 Homo sapiens P27986-2 32814053
Intra
SMAD3 P84022 SETD2 Homo sapiens Q9BYW2 21988832
Intra
SMAD3 P84022 RNF31 Homo sapiens Q96EP0 21988832
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant SMAD3 Proteins

Art. -Nr. Produktname Accession Reinheit
HY-P71323 SMAD3 Protein, Human/Mouse/Rat (Flag-His) P84022-1/Q8BUN5/P84025 (S2-S425) ≥ 85%, as determined by reducing SDS-PAGE.

SMAD3 Antibodies

Art. -Nr. Produktname Anwendung Reactivity
HY-P80325 Smad3 Antibody (YA075) WB, ICC/IF, IHC-P, FC Human, Mouse, Rat
HY-P80477 Phospho-Smad3 (Ser423/Ser425) Antibody (YA151) WB, ICC/IF, IHC-P Human, Mouse
HY-P80854A Phospho-Smad3 (Ser423/425) Antibody (YA3477) WB, IHC-P, ICC/IF Human, Mouse
HY-P84443 Smad3 Antibody (YA4140) WB, ICC/IF, ELISA Human, Mouse
HY-P84443A Smad3 Antibody (YA4140)(PBS only) WB, ICC/IF, ELISA Human, Mouse
HY-P85766 Smad3 Antibody (YA5458) WB, ICC/IF, ELISA Human, Rat, Mouse
HY-P86070 Phospho-Smad3(S425) Antibody (YA5762) IHC-P, ICC/IF Human, Mouse, Rat
HY-P86122 Smad3 Antibody (YA5814) WB, IHC-P, ICC/IF, IP, ELISA Human, Mouse, Rat
HY-P86139 Phospho-Smad2/3(Thr8) Antibody (YA5831) WB, ICC/IF, IP, ELISA Human, Mouse, Rat

Related Diseases

Diseases Alias
Loeys-Dietz Syndrome 3
  • LDS3

  • Aneurysms-Osteoarthritis Syndrome

  • Loeys-Dietz Syndrome With Osteoarthritis

  • Aneurysm-Osteoarthritis Syndrome

  • Lds1c

  • Loeys-Dietz Syndrome, Type 3

  • Loeys-Dietz Syndrome, Type 1c, Formerly

  • Lds1c, Formerly

  • Loeys-Dietz Syndrome Type 1c

  • Loeys-Dietz Syndrome Type 3

  • Aneurysm - Osteoarthritis Syndrome

  • Loeys-Dietz Syndrome, Type 1c

  • Aos

  • Loeys-Dietz Syndrome 1c

Aortic Aneurysm, Familial Thoracic 1
  • Thoracic Aortic Aneurysm

  • Annuloaortic Ectasia

  • Familial Thoracic Aortic Aneurysm And Aortic Dissection

  • Familial Aortic Dissection

  • Familial Taad

  • Familial Thoracic Aortic Aneurysm

  • Congenital Aneurysm Of Ascending Aorta

  • Familial Aortic Aneurysm

  • Familial Thoracic Aortic Aneurysm And Dissection

  • Aortic Aneurysm, Thoracic

  • AAT1

  • Faa1

  • Aortic Dissection, Familial

  • Aortic Aneurysm, Familial Thoracic

  • Aneurysm, Thoracic Aortic

  • Faa

  • Ftaad

  • Taa

  • Taad

  • Cystic Medial Necrosis Of Aorta

  • Familial Non-Syndromic Thoracic Aortic Aneurysm And Aortic Dissection

  • Aortic Aneurysm Thoracic

  • Familial Aortic Aneurysms

  • Aneurysm, Aortic, Thoracic, Familial, Type 1

  • Aneurysm Of Thoracic Aorta

  • Intrathoracic Aneurysm

  • Thoracic Aorta Aneurysm

  • Thoracic Aortic Aneurysm Without Rupture

  • Thoracic Aneurysm

  • Thorax Arterial Aneurysm

  • Thoracic Artery Aneurysm

  • Thoracic Arterial Aneurysm

  • Thorax Aneurysm

  • Thorax Aortic Aneurysm

  • Dissection Of Thoracic Aorta

Aortic Aneurysm
  • Aortic Rupture

  • Thoracoabdominal Aortic Aneurysm, Ruptured

  • Ruptured Aortic Aneurysm

  • Aortic Aneurysms

  • Aortic Aneurysm Without Mention Of Rupture Nos

  • Ruptured Abdominal Aortic Aneurysm

  • Aortic Aneurysm, Ruptured

  • Ruptured Thoracic Aortic Aneurysm

Ehlers-Danlos Syndrome
  • Eds

  • Cutis Hyperelastica

  • Elastic Skin

  • Ehlers-Danlos Syndromes

  • Ed Syndrome

  • Ehlers Danlos Syndrome

  • Ehlers Danlos Disease

  • Eds - [Ehlers-Danlos Syndrome]

Aortic Aneurysm, Familial Thoracic 4
  • AAT4

  • Faa4

  • Aortic Aneurysm/Aortic Dissection And Patent Ductus Arteriosus

  • Familial Aortic Aneurysm 4

  • Non-Syndromic Thoracic Aortic Aneurysms And Dissection

  • Taad

  • Thoracic Aortic Aneurysms And Dissection

  • Thoracic Aortic Aneurysms And Dissections

  • Aneurysm, Aortic, Thoracic, Familial, Type 4

Connective Tissue Disease
  • Connective Tissue Diseases

  • Connective Tissue Disorder

  • Abnormality Of Connective Tissue

  • Disorder Of Connective Tissue

  • Connective Tissue Disorders

Loeys-Dietz Syndrome
  • Loeys-Dietz Aortic Aneurysm Syndrome

  • Lds

  • Aortic Aneurysm Syndrome Due To Tgf-Beta Receptors Anomalies

  • Furlong Syndrome

Renal Fibrosis
Melorheostosis
  • Candle Wax Disease

  • Flowing Hyperostosis

  • Hyperostosis, Monomelic

  • Leri Syndrome

  • Leri'S Disease

  • Melorheostoses

  • Melorheostosis Of Leri

  • Melorheostosis, Isolated

  • Periostitis

  • Monomelic

  • Rheostosis

Osteoarthritis
  • Osteoarthrosis

  • Degenerative Joint Disease

  • Hypertrophic Arthritis

  • Arthropathy

  • Degenerative Polyarthritis

  • Degenerative Arthritis

  • Osteoarthrosis And Allied Disorder

  • Arthritis, Degenerative

  • Oa

  • Osteoarthritis Deformans

  • Osteoarthrosis Deformans

  • Kashin-Beck Disease

Adenocarcinoma
  • Adenocarcinomas

  • Adenoacanthoma Of Unspecified Site

  • Adenocarcinoid Of Unspecified Site

  • Adenocarcinoid Tumour Of Unspecified Site

  • Adenocarcinoma And Carcinoid Combined Of Unspecified Site

  • Adenocarcinoma Nos

Clear Cell Adenocarcinoma
  • Mesonephroma

  • Water-Clear Cell Adenocarcinoma

  • Adenocarcinoma, Clear Cell

  • Malignant Mesonephroma

  • Mesonephroid Clear Cell Carcinoma

  • Mesonephroma, Malignant

  • Water-Clear Cell Carcinoma

  • Wolffian Duct Neoplasm

  • Adenocarcinoma Clear Cell

  • Mesonephric Tumor

Obstructive Nephropathy
  • Con

  • Congenital Obstructive Nephropathy

  • Nephropathy Obstructive

Pulmonary Fibrosis
  • Fibrosis Of Lung

Pelvic Organ Prolapse
  • Rectal Prolapse

  • Pelvic Organ Prolapse, Susceptibility To, 1

  • Pelvic Organ Prolapse, Susceptibility To

  • Prolapse Of Vagina And Rectum

  • Vaginal Prolapse

  • Pelvic Organ Prolapse 1

  • Procidentia, Rectum

  • Prolapse Of Rectal Mucosa

  • Procidentia Of Rectum

  • Rectal Mucosa Prolapse

  • Rectum Prolapse

  • Procidentia Rectum

  • Rp - [Rectal Prolapse]

  • Male Proctocele

  • Male Rectocele

  • Proctoptosis

  • Female Genital Prolapse

  • Female Prolapse

  • Incompetence Of Pelvic Fundus

  • Relaxation Of Perineum

  • Deficiency Of Perineum

Colitis
Ureteral Disease
  • Ureteral Diseases

  • Ureteral Disorders

  • Disorder Of Ureter

Ulcerative Colitis
  • Colitis Gravis

  • Left Sided Ulcerative Colitis

  • Left-Sided Ulcerative Colitis

  • Idiopathic Proctocolitis

  • Inflammatory Bowel Disease, Ulcerative Colitis Type

  • Uc

  • Colitis Ulcerative

  • Colitis, Ulcerative

  • Chronic Left-Sided Ulcerative Colitis

  • Uc - [Ulcerative Colitis]

  • Chronic Ulcerative Enteritis

  • Mucosal Proctocolitis

  • Ulcerative Mucosal Proctocolitis

  • Left Hemicolitis

Colorectal Cancer
  • Colon Cancer

  • Colorectal Carcinoma

  • Colon Carcinoma

  • Colorectal Cancer, Susceptibility To

  • Carcinoma Of Colon

  • CRC

  • Colorectal Cancer With Chromosomal Instability, Somatic

  • Colon Cancer, Somatic

  • Colon Cancer, Susceptibility To

  • Colonic Neoplasms

  • Colorectal Neoplasms

  • Colorectal Cancer, Somatic

  • Colon Cancer, Advanced, Somatic

  • Colonic Carcinoma

  • Colorectal Carcinomas

  • Colon Cancers

  • Colorectal Cancers

  • Cancer, Colorectal, Somatic

  • Cancer, Colon

  • Cancer, Colorectal, Susceptibility To

  • Colorectal Neoplasm

  • Colonic Neoplasm

  • Malignant Tumor Of Colon

Keloid Disorder
  • Keloid

  • Cheloid

  • Keloid Scar

  • Non-Surgical Keloid

Pancreatic Cancer
  • Pancreatic Carcinoma

  • Carcinoma Of Pancreas

  • Familial Pancreatic Carcinoma

  • Pancreatic Neoplasm

  • Pancreatic Carcinoma, Familial

  • Malignant Neoplasm Of Pancreas

  • Pancreatic Acinar Carcinoma

  • Pancreatic Tumor

  • Familial Pancreatic Cancer

  • Neoplasm Of The Pancreas

  • Cancer Of The Pancreas

  • Pancreatic Carcinoma, Somatic

  • Pancreatic Cancer, Somatic

  • Ca Body Of Pancreas

  • Ca Head Of Pancreas

  • Ca Tail Of Pancreas

  • Malignant Neoplasm Of Body Of Pancreas

  • Malignant Neoplasm Of Head Of Pancreas

  • Malignant Neoplasm Of Tail Of Pancreas

  • Pancreas Neoplasm

  • Exocrine Cancer

  • Exocrine Pancreas Carcinoma

  • Hereditary Pancreatic Cancer

  • Hereditary Pancreatic Carcinoma

  • PNCA

  • Pancreatic Cancer, Susceptibility To

  • Carcinoma Of Head Of Pancreas

  • Pancreatic Neoplasms

  • Pancreatic Tumors

  • Cancer, Pancreatic

  • Cancer Of Pancreas

  • Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site

Adenoma
  • Acinar Cell Adenoma

  • Adenomas

  • Acinic Cell Adenoma

Endometrial Cancer
  • Endometrial Carcinoma

  • Endometrial Neoplasm

  • Malignant Neoplasm Of Endometrium

  • Endometrioid Carcinoma

  • Endometrial Neoplasms

  • Carcinoma, Endometrioid

  • Endometrial Cancer, Familial

  • Endometrial Carcinoma, Somatic

  • Endometrial Cancer, Susceptibility To

  • Endometrial Ca

  • Malignant Endometrial Neoplasm

  • Neoplasm Of Endometrium

  • Primary Malignant Neoplasm Of Endometrium

  • Tumor Of Endometrium

  • Carcinoma Of The Endometrium

  • Endometrioid Carcinoma Of Female Reproductive System

  • ENDMC

  • Carcinoma Endometrioid

  • Endometrial Cancers

  • Cancer, Endometrial

  • Uterine Corpus Cancer

Cleidocranial Dysplasia
  • Cleidocranial Dysostosis

  • CLCD

  • Cleidocranial Dysplasia, Forme Fruste, Dental Anomalies Only

  • Cleidocranial Dysplasia, Forme Fruste, With Brachydactyly

  • CCD

  • Marie-Sainton Disease

  • Dysplasia Cleidocranial

  • Dento-Osseous Dysplasia

  • Marie-Sainton Syndrome

  • Dysplasia, Cleidocranial

Loeys-Dietz Syndrome 4
  • LDS4

  • Aneurysm, Aortic And Cerebral, With Arterial Tortuosity And Skeletal Manifestations

  • Loeys-Dietz Syndrome Type 4

  • Aortic And Cerebral Aneurysm With Arterial Tortuosity And Skeletal Manifestations

  • Loeys-Dietz Syndrome, Type 4

Loeys-Dietz Syndrome 5
  • Rienhoff Syndrome

  • LDS5

  • Rnhf

  • Reinhoff Syndrome

  • Loeys-Dietz Syndrome, Type 5

Pulmonary Hypertension
  • Primary Pulmonary Hypertension

  • Hypertension Pulmonary

  • Hypertension, Pulmonary

  • Hypertension, Pulmonary, Primary

  • Idiopathic Pulmonary Hypertension

  • Idiopathic Pulmonary Arterial Hypertension

  • Pulmonary Htn - [Hypertension]

Systemic Scleroderma
  • Scleroderma

  • Progressive Systemic Sclerosis

  • Systemic Sclerosis

  • Scleroderma, Systemic

  • Scleroderma Syndrome

  • Dermatosclerosis

  • Familial Progressive Scleroderma

  • Progressive Scleroderma

  • Scleroderma Disease

  • Scleroderma, Localized

  • Diffuse Scleroderma

  • Scleroderma, Familial Progressive

Multiple Endocrine Neoplasia, Type I
  • Multiple Endocrine Neoplasia Type 1

  • MEN1

  • Wermer Syndrome

  • Multiple Endocrine Neoplasia 1

  • Multiple Endocrine Neoplasia, Type 1

  • Men I

  • Endocrine Adenomatosis, Multiple

  • Mea I

  • Men Type I

  • Wermer'S Syndrome

  • Men1 Syndrome

  • Multiple Endocrine Adenomatosis

  • Endocrine Adenomatosis Multiple

  • Men 1

  • Familial Multiple Endocrine Neoplasia Type I

  • Neoplasia, Endocrine, Multiple, Type 1

  • Multiple Endocrine Neoplasia

Urinary Tract Obstruction
  • Obstructive Uropathy

  • Urinary Obstruction

  • Urologic Diseases

Hepatocellular Carcinoma
  • Liver Cancer

  • Primary Liver Cancer

  • HCC

  • Hepatoma

  • Malignant Neoplasm Of Liver

  • Liver Neoplasms

  • Cancer, Hepatocellular

  • Liver Cell Carcinoma

  • Lcc

  • Hepatoblastoma, Somatic

  • Hepatic Cancer

  • Primary Malignant Neoplasm Of Liver

  • Rare Tumor Of Liver And Intrahepatic Biliary Tract

  • Hepatocellular Carcinoma, Somatic

  • Hepatocellular Carcinoma, Childhood Type, Somatic

  • Hepatocellular Cancer, Somatic

  • Ca Liver - Primary

  • Hepatic Neoplasm

  • Malignant Hepato-Biliary Neoplasm

  • Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

  • Malignant Neoplasm Of Liver, Primary

  • Malignant Tumor Of Liver

  • Neoplasm Of Liver

  • Non-Resectable Primary Hepatic Malignant Neoplasm

  • Resectable Malignant Neoplasm Of Liver

  • Resectable Malignant Neoplasm Of The Liver

  • Primary Liver Carcinoma

  • Primary Malignant Liver Neoplasm

  • Primary Cancer Of Liver

  • Primary Tumor Of The Liver

  • Rare Tumor Of Liver And Ibt

  • Hepatocellular Cancer

  • Neoplasm Of The Liver

  • Carcinoma, Hepatocellular

  • Hepatomas

  • Liver Neoplasm

  • Liver Carcinoma

  • Liver And Intrahepatic Biliary Tract Carcinoma

  • Malignant Hepatobiliary Neoplasm

  • Adult Primary Hepatocellular Carcinoma

  • Hepatoblastoma

  • Carcinoma Of Liver

  • Malignant Liver Tumour

  • Malignant Hepatic Tumour

Autosomal Dominant Intellectual Developmental Disorder 19
  • Autosomal Dominant Non-Syndromic Intellectual Disability 19

  • Autosomal Dominant Mental Retardation 19

  • Mrd19

Hepatitis D
  • Delta Hepatitis

  • Hepatitis Delta

  • Hdv

  • Hepatitis D Virus

  • Hepatitis D Infection

Aortic Dissection
Loeys-Dietz Syndrome 2
  • LDS2

  • Aat3

  • Marfan Syndrome Type 2

  • Aortic Aneurysm, Familial Thoracic 3

  • Marfan Syndrome Type Ii

  • Loeys-Dietz Syndrome Type 2

  • Mfs2

  • Marfan Syndrome, Type Ii, Formerly

  • Familial Throacic Aortic Aneurysm 3

  • Familial Aortic Aneurysm Thoracic Type 3

  • Taad2

  • Thoracic Aortic Aneurysms And Dissection 2

  • Aneurysm, Aortic, Thoracic, Familial, Type 3

  • Loeys-Dietz Syndrome, Type 2

Craniosynostosis
  • Premature Closure Of Cranial Sutures

  • Craniostenosis

  • Craniosynostosis Syndrome

  • Cso

  • Craniosynostoses

  • Congenital Ossification Of Cranial Sutures

  • Congenital Ossification Of Sutures Of Skull

  • Craniostosis

  • Imperfect Fusion Of Skull

  • Congenital Imperfect Closure Skull

  • Imperfect Closure Skull

  • Premature Closure Cranium Sutures

  • Deficiency Of Craniofacial Axis

Loeys-Dietz Syndrome 1
  • Furlong Syndrome

  • Loeys-Dietz Aortic Aneurysm Syndrome

  • LDS1

  • Aat5

  • Loeys-Dietz Syndrome Type 1

  • Aortic Aneurysm, Familial Thoracic 5

  • Familial Throacic Aortic Aneurysm 5

  • Loeys-Dietz Syndrome

  • Aortic Aneurysm Syndrome, Loeys-Dietz Type

  • Familial Thoracic Aortic Aneurysm 5

  • Ldas

  • Marfanoid Disorder-Craniosynostosis Syndrome

  • Aneurysm, Aortic, Thoracic, Familial, Type 5

  • Loeys-Dietz Syndrome, Type 1

  • Loeys-Dietz Syndrome, Type 2a

Osteoporosis
  • Postmenopausal Osteoporosis

  • Osteoporosis, Postmenopausal

  • Bone Mineral Density Quantitative Trait Locus

  • Bmnd

  • Osteoporosis, Involutional

  • Osteoporosis, Susceptibility To

  • Osteoporosis, Postmenopausal, Susceptibility

  • Bone Mineral Density Variation Qtl, Osteoporosis

  • OSTEOP

  • Involutional Osteoporosis

  • Senile Osteoporosis

  • Osteoporosis Postmenopausal

  • Bone Mineral Density, Quantitative Trait Locus

  • Osteoporosis, Senile

  • Idiopathic Osteoporosis

  • Bone Rarefaction Nos

  • Type 1 Osteoporosis

Arterial Tortuosity Syndrome
  • Arterial Tortuosity

  • Ats

  • ATORS

  • Tortuosity, Arterial, Syndrome

Peyronie'S Disease
  • Induratio Penis Plastica

  • Peyronie Disease

  • Peyronies Disease

  • Peyronie'S Fibromatosis

  • Penile Induration

  • Balanitis Xerotica Obliterans

Rhabdomyosarcoma
Aortic Valve Disease 1
  • Aortic Valve Disease

  • Bicuspid Aortic Valve

  • Aortic Valve Disorder

  • AOVD1

  • Bav

  • Bicuspid Aortic Valve Disease

  • Familial Bicuspid Aortic Valve

  • Aortic Valve Calcification

  • Aovd

  • Aortic Valve, Bicuspid

  • Aortic Valve, Calcification Of

  • Aortic Stenosis, Calcific

  • Familial Bav

  • Calcific Aortic Stenosis

  • Calcification Of Aortic Valve

  • Abnormality Of The Aortic Valve

  • Aortic Valve Disease, Type 1

  • Aortic Valve Disease 2

  • Bicommissural Aortic Valve

Colon Adenocarcinoma
  • Adenocarcinoma Of Colon

  • Adenocarcinoma Of The Colon

  • Colonic Adenocarcinoma

Ovarian Cancer
  • Ovarian Carcinoma

  • Ovarian Neoplasm

  • Malignant Tumour Of Ovary

  • Cancer Of The Ovary

  • Epithelial Ovarian Cancer

  • Neoplasm Of Ovary

  • Ovarian Neoplasms

  • Ovarian Cancers

  • Malignant Neoplasm Of Ovary

  • Primary Malignant Neoplasm Of Ovary

  • Ovarian Cancer, Somatic

  • Malignant Ovarian Tumor

  • Ovary Neoplasm

  • Primary Ovarian Cancer

  • Tumor Of The Ovary

  • Malignant Neoplasm Of The Ovary

  • Malignant Tumor Of The Ovary

  • Ovarian Malignant Tumor

  • OC

  • Ovarian Carcinomas

  • Cancer, Ovarian

  • Cancer Of Ovary

  • Ovary Cancer

  • Ca Ovary

Aortic Disease
  • Aortic Diseases

  • Aortic Disorder

  • Disorder Of The Aorta

Gastric Cancer
  • Stomach Cancer

  • Gastric Carcinoma

  • Stomach Carcinoma

  • Gastric Cancer, Somatic

  • Gastric Neoplasm

  • Carcinoma Of Stomach

  • Stomach Neoplasms

  • Malignant Neoplasm Of Stomach

  • Gastric Cancer Risk After H. Pylori Infection

  • Cancer Of The Stomach

  • Adult Stomach Cancer

  • Adult Stomach Carcinoma

  • GASC

  • Gastric Cancer Intestinal

  • Gastric Cancers

  • Gastric Carcinomas

  • Cancer, Gastric

  • Stomach Neoplasm

  • Malignant Neoplasm Of Body Of Stomach

  • Malignant Tumor Of Lesser Curve Of Stomach

  • Gastrocarcinoma Of Unspecified Site

  • Leather Bottle Stomach

  • Carcinoma Of Fundus Of Stomach

  • Cancer Of Fundus Of Stomach

  • Primary Malignant Neoplasm Of Body Of Stomach

  • Cancer Of Body Of Stomach

  • Primary Malignant Neoplasm Of Pyloric Antrum

  • Pyloric Antrum Cancer

  • Malignant Tumour Of Stomach

Prostate Cancer
  • Prostate Carcinoma

  • Prostate Cancer, Familial

  • Prostate Neoplasm

  • Prostate Cancer, Somatic

  • Prostate Cancer, Susceptibility To

  • Prostatic Cancer

  • Prostatic Neoplasms

  • Hereditary Prostate Cancer

  • Prostatic Neoplasm

  • Cancer Of Prostate

  • Carcinoma Of Prostate

  • Familial Prostate Cancer

  • Familial Prostate Carcinoma

  • Malignant Tumor Of Prostate

  • Malignant Neoplasm Of Prostate

  • Prostate Cancer, Familial, Susceptibility To

  • Malignant Tumor Of The Prostate

  • Ngp - New Growth Of Prostate

  • Tumor Of The Prostate

  • Prostate Cancer, Hereditary

  • Cancer Of The Prostate

  • Malignant Neoplasm Of The Prostate

  • Prostatic Carcinoma

  • PC

  • Prca

  • Cancer, Prostate

  • Malignant Prostatic Tumour

  • Malignant Tumour Of Prostate

  • Primary Prostate Cancer

  • Primary Malignant Neoplasm Of Prostate

  • Prostate Gland Cancer

Orthostatic Intolerance
  • Mitral Valve Prolapse

  • Neurocirculatory Asthenia

  • Mitral Valve Prolapse Syndrome

  • Irritable Heart

  • Systolic Click-Murmur Syndrome

  • Soldiers Heart

  • Cardiovascular Malfunction Arising From Mental Factors

  • Cardiovascular Neurosis

  • Da Costa'S Syndrome

  • Krishaber'S Disease

  • Barlow'S Syndrome

  • Floppy Mitral Valve

  • Mitral Leaflet Syndrome

  • Myxomatous Mitral Valve Prolapse

  • Postural Orthostatic Tachycardia Syndrome Due To Net Deficiency

  • Familial Orthostatic Tachycardia Due To Norepinephrine Transporter Deficiency

  • Orthostatic Intolerance Due To Net Deficiency

  • Pots Due To Net Deficiency

  • OI

  • Intolerance, Orthostatic

  • Mitral Valve Prolapse, Familial, X-Linked

  • Ballooning Mitral Valve

  • Barlow Syndrome

  • Flail Mitral Leaflet

  • Myxomatous Mitral Valve

  • Mitral Valve Prolapse-Click Syndrome

  • Prolapsing Mitral Valve Leaflet Syndrome

  • Billowing Mitral Valve Leaflet

  • Posterior Mitral Leaflet Deformity

  • Ballooning Posterior Leaflet Syndrome

  • Blue Valve Syndrome

  • Floppy Mitral Valve Syndrome

  • Mitral Valvular Prolapse

  • Systolic Click Syndrome

Breast Cancer
  • Breast Carcinoma

  • Male Breast Cancer

  • Breast Cancer, Familial

  • Malignant Neoplasm Of Breast

  • Breast Cancer, Susceptibility To

  • Breast Cancer, Early-Onset

  • Malignant Tumor Of Breast

  • Carcinoma Of Male Breast

  • Breast Cancer, Invasive Ductal

  • Breast Cancer, Protection Against

  • Breast Cancer, Somatic

  • Breast Cancer, Male

  • Breast Cancer, Lobular, Somatic

  • Breast Tumor

  • Mammary Cancer

  • Mammary Tumor

  • Malignant Neoplasm Of Male Breast

  • Mammary Carcinoma

  • Male Breast Carcinoma

  • Familial Cancer Of Breast

  • Invasive Ductal Breast Carcinoma

  • Breast Cancer Susceptibility

  • Breast Cancer, Male, Susceptibility To

  • Breast Cancer, Early-Onset, Susceptibility To

  • Malignant Tumor Of The Breast

  • Mammary Neoplasm

  • Primary Breast Cancer

  • Neoplasm Of Male Breast

  • Carcinoma Of Breast

  • Breast Cancer In Men

  • Familial Breast Cancer

  • Cancer Of Breast

  • BC

  • Breast Cancer Familial

  • Breast Cancer Familial Male

  • Breast Cancer, Familial Male

  • Breast Male Carcinoma

  • Breast Neoplasms

  • Breast Neoplasms, Male

  • Mammary Tumors

  • Mammary Carcinomas

  • Cancer, Breast

  • Cancer, Breast, Susceptibility

  • Invasive Breast Ductal Carcinoma

  • Breast Neoplasm

  • Susceptibility To Breast Cancer

  • Mammary Neoplasms

  • Animal Mammary Neoplasms

  • Primary Malignant Neoplasm Of Breast

  • Infiltrating Ductal Carcinoma Of Breast

  • Infiltrating Duct Carcinoma Of Unspecified Site

  • Infiltrating Ductular Carcinoma Of Unspecified Site

  • Invasive Breast Carcinoma Of No Special Type

  • Microinvasive Carcinoma Of Breast

  • Carcinoma With Apocrine Differentiation

Interstitial Lung Disease 2
  • Idiopathic Pulmonary Fibrosis

  • Ipf

  • Fibrocystic Pulmonary Dysplasia

  • Pulmonary Fibrosis, Idiopathic

  • Pulmonary Fibrosis, Idiopathic, Susceptibility To

  • Cryptogenic Fibrosing Alveolitis

  • ILD2

  • Idiopathic Pulmonary Fibrosis, Familial

  • Fibrosing Alveolitis, Cryptogenic

  • Uip

  • Fibrosing Alveolitis

  • Interstitial Pneumonitis, Usual

  • Familial Idiopathic Pulmonary Fibrosis

  • Idiopathic Fibrosing Alveolitis, Chronic Form

  • Usual Interstitial Pneumonia

  • Fibrosing Alveolitis Cryptogenic

  • Hamman-Rich Disease

  • Idiopathic Pulmonary Fibrosis Familial

  • Interstitial Pneumonitis Usual

  • Fibrosis Idiopathic Pulmonary

  • Fibrosis, Pulmonary, Idiopathic

  • Hamman-Rich Syndrome

  • Chronic Idiopathic Pulmonary Fibrosis

  • Acute Interstitial Pneumonia

  • Interstitial Pulmonary Fibrosis

  • Ipf - [Idiopathic Pulmonary Fibrosis]

  • Idiopathic Lung Fibrosis

  • Fibrosing Lung Disease

  • Pulmonary Fibrosis Nos

  • Fibrosing Pneumonitis

Arthrogryposis, Distal, Type 2b3
  • DA2B3

  • Distal Arthrogryposis Type 2b3

  • Arthrogryposis, Distal, 2b3

Lipoprotein Quantitative Trait Locus
  • Coronary Artery Disease

  • Coronary Artery Anomaly

  • Coronary Artery Disease, Susceptibility To

  • Myocardial Ischemia

  • Congenital Anomaly Of Coronary Artery

  • Coronary Arteriosclerosis

  • Coronary Disease

  • Coronary Heart Disease

  • Coronary Artery Disorder

  • LPAQTL

  • Lpa Deficiency, Congenital

  • Coronary Artery Abnormality

  • Coronary Artery Anomaly, Congenital

  • Chd

  • Coronary Syndrome

  • Congenital Malformations Of Coronary Vessels

  • Malformation Of Coronary Vessels

  • Congenital Coronary Artery Anomaly

  • Congenital Coronary Artery Deformity

  • Congenital Coronary Artery Disorder

  • Abnormal Coronary Artery

  • Congenital Coronary Artery Malposition

  • Congenital Coronary Disease

  • Congenital Anomaly Of Coronary Arteries

Myocardial Infarction
  • Heart Attack

  • Myocardial Infarction, Susceptibility To

  • Myocardial Infarction 1

  • Myocardial Infarction, Protection Against

  • Myocardial Infarction, Decreased Susceptibility To

  • Myocardial Infarction, Decreased

  • Myocardial Infarct

  • MCI1

  • Premature Myocardial Infarction

  • Myocardial Infarction, Susceptibility To, Type 1

Cowden Syndrome 6
  • CWS6

  • Cowden Syndrome, Type 6

Stickler Syndrome, Type I
  • Stickler Syndrome 1

  • Stickler Syndrome Type 1

  • STL1

  • Aom

  • Stickler Syndrome, Type 1

  • Stickler Syndrome, Vitreous Type 1

  • Stickler Syndrome, Membranous Vitreous Type

  • Arthroophthalmopathy, Hereditary Progressive

  • Arthro-Ophthalmopathy Hereditary Progressive

  • Stickler Syndrome Membranous Vitreous Type

  • Stickler Syndrome Type I

  • Stickler Syndrome Vitreous Type 1

Cystic Fibrosis
  • Mucoviscidosis

  • CF

  • Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis

  • Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis

  • Cystic Fibrosis Lung Disease, Modifier Of

  • Cystic Fibrosis Of Pancreas

  • Fibrocystic Disease Of Pancreas

  • Cf - [Cystic Fibrosis]

  • Cystic Fibrosis Nos

  • Fibrocystic Disease

  • Fibrocystic Disease Of The Pancreas

  • Mucoviscidosis Of Pancreas

  • Nonproliferative Fibrocystic Disease

  • Pancreatic Cystic Fibrosis

Hereditary Hemorrhagic Telangiectasia
  • Rendu-Osler-Weber Disease

  • Hht

  • Osler-Weber-Rendu Disease

  • Telangiectasia, Hereditary Hemorrhagic

  • Osler Hemorrhagic Telangiectasia Syndrome

  • Orw Disease

  • Osler Weber Rendu Syndrome

  • Osler-Rendu-Weber Disease

  • Osler-Weber-Rendu Syndrome

  • Rendu-Osler Disease

  • Telangiectasia Hereditary Hemorrhagic

  • Telangiectasia Hemorrhagic, Hereditary

  • Hht - [Hereditary Haemorrhagic Telangiectasia]

  • Osler Haemorrhagic Telangiectasia Syndrome

Medulloblastoma
  • MDB

  • Cpnet

  • Localized Primitive Neuroectodermal Tumor

  • Classic Medulloblastoma

  • Medulloblastoma Predisposition Syndrome

  • Medulloblastoma, Somatic

  • Brain Medulloblastoma

  • Cns Pnet

  • Infratentorial Primitive Neuroectodermal Tumor

  • Neuroectodermal Tumors, Primitive

  • Medulloblastomas

  • Desmoplastic Medulloblastoma

  • Medulloblastoma, With Extensive Nodularity

  • Medulloblastoma Of Unspecified Site

  • Medullomyoblastoma Of Unspecified Site

Diabetes Mellitus
  • Diabetes

Squamous Cell Carcinoma, Head And Neck
  • Squamous Cell Carcinoma Of The Head And Neck

  • HNSCC

  • Head And Neck Squamous Cell Carcinoma

  • Squamous Cell Carcinoma Of Lip

  • Squamous Cell Carcinoma, Head And Neck, Somatic

  • Carcinoma Of The Head And Neck

  • Squamous Cell Carcinomas Of Head And Neck

  • Scchn

  • Squamous Cell Carcinoma Of The Hypopharynx

  • Squamous Cell Carcinoma Of The Oropharynx

  • Squamous Cell Carcinoma Of Salivary Glands

  • Squamous Cell Carcinoma Of The Nasal Cavity And Paranasal Sinuses

  • Squamous Cell Carcinoma Of The Nasal Cavity And Sinuses

  • Squamous Cell Carcinoma Of The Oral Cavity

  • Squamous Cell Carcinoma Of The Lip

  • Carcinoma, Squamous Cell Of Head And Neck

  • Lip Squamous Cell Carcinoma

  • Carcinoma, Squamous Cell, Head And Neck

  • Salivary Gland Squamous Cell Carcinoma

  • Cancer Of Head And Neck

  • Squamous Cell Carcinoma Of Oropharynx Nos

Hypertension, Essential
  • Essential Hypertension

  • Hypertension

  • High Blood Pressure

  • Hypertension, Essential, Susceptibility To

  • Hypertensive Disease

  • Primary Hypertension

  • EHT

  • Hypertension, Salt-Sensitive Essential, Susceptibility To

  • Hyperpiesia

  • Idiopathic Hypertension

  • Hypertensive Disorder

  • Hypertension, Essential, Susceptibility To, 3

  • Hypertension, Essential 3

  • Hypertension, Essential, Salt-Sensitive

  • Hypertension, Essential, Susceptibility To, 6

  • Hypertension, Essential 6

  • Hypertension, Salt-Sensitive Essential

  • Hypertension, Susceptibility To

  • Hypertension, Essential, Susceptibility To, 4

  • Hypertension, Essential 4

  • Hypertension, Essential, Susceptibility To, 2

  • Hypertension, Essential 2

  • Hypertension, Essential, Susceptibility To, 1

  • Hypertension, Essential 1

  • Hypertension, Essential, Susceptibility To, 5

  • Hypertension, Essential 5

  • Htn

  • Vascular Hypertensive Disorder

  • Systemic Primary Arterial Hypertension

  • Hbp - [High Blood Pressure]

  • Systemic Arterial Hypertensive Disorder

  • Elevated Blood Pressure

  • Arterial Hypertension Nos

  • Hypertension Nos

  • Benign Hypertension

  • Systemic Arterial Hypertension

  • Systemic Hypertension

  • Artery Htn

  • Benign Htn

  • Vascular Htn

  • Vascular Hypertension

  • Cholesterol Hypertension

  • Cholesterol Htn

  • Idiopathic Htn

  • Malignant Hypertension

  • Malignant Htn

  • Raised Blood Pressure

  • Cardiovascular Hypertension

  • Primary Htn - [Hypertension]

  • High Arterial Tension

  • High Blood Pressure Disorder

  • Ht - [Hypertension]

  • Htn - [Hypertension]

  • Hypertensive Vascular Disease

  • Hypertensive Vascular Degeneration

Orofacial Cleft
  • Cleft, Orofacial

Patent Ductus Arteriosus 1
  • Patent Ductus Arteriosus

  • PDA1

  • Pda

  • Ductus Arteriosus, Patent

  • Patent Ductus Arteriosus, Susceptibility To

  • Patent Ductus Botalli

  • Patency Of The Ductus Arteriosus

  • Patent Ductus Arteriosus Familial

  • Ductus Arteriosus Patent

  • Patent Ductus Arteriosus - Persisting Type

Colonic Benign Neoplasm
  • Colon Neoplasm

  • Colonic Mass

  • Colonic Tumor

  • Neoplasm Of Colon

  • Neoplasm Of The Colon

  • Colonic Neoplasms

  • Colon Cancer

  • Colon Carcinoma Nos

  • Colonic Cancer

  • Metastatic Colon Cancer Nos

Dilated Cardiomyopathy
  • Familial Dilated Cardiomyopathy

  • Primary Dilated Cardiomyopathy

  • Idiopathic Dilated Cardiomyopathy

  • Congestive Cardiomyopathy

  • Idiopathic Dilation Cardiomyopathy

  • Primary Familial Dilated Cardiomyopathy

  • Cardiomyopathy, Dilated

  • DCM

  • Cardiomyopathy, Familial Dilated

  • Dilated Cardiomyopathy, Familial

  • Hypokinetic Dilated Cardiomyopathy, Familial

  • Familial Idiopathic Cardiomyopathy

  • Fdc

  • Cardiomyopathy, Familial Idiopathic

  • Idiopathic Cardiomegaly

  • Dilated Congestive Cardiomyopathy

  • Chronic Dilated Cardiomyopathy

  • Ccm - [Congestive Cardiomyopathy]

  • Cocm - [Congestive Cardiomyopathy]

  • Dcm - [Dilated Cardiomyopathy]

  • Dilated-Hypokinetic Cardiomyopathy

  • Congestive Idiopathic Cardiomyopathy

  • Primary Idiopathic Dilated Cardiomyopathy

Nervous System Disease
  • Abnormality Of The Nervous System

  • Nervous System Diseases

  • Nervous System Disorder

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SMAD3 RGD RGD:3032
Macaca mulatta SMAD3 VGNC VGNC:77811
Canis familiaris SMAD3 VGNC VGNC:46520
Mus musculus SMAD3 MGD MGI:1201674
Bos taurus SMAD3 VGNC VGNC:34976
Felis catus SMAD3 VGNC VGNC:68131
Others SMAD3 NCBI