GSK190937
GSK190937 is a type II platelet-derived growth factor receptor alpha (PDGFRA) human kinase inhibitor with antimalarial activity. GSK190937 can inhibit the formation of hemozoin in the malaria parasite, resulting in the accumulation of free hemoglobin within the malaria parasite. GSK190937 shows IC50 values of 0.22, 0.59 and 0.25 μM against P. falciparum NF54, K1 and Dd2 parasite. GSK190937 shows an IC50 of 25 μM for CHO cells. GSK190937 can be used for research of malaria.
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- CAS. Nr.: 2651234-01-2
- Formel: C22H20Cl2N4O
- Molecular Weight:427.33
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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PDGFRα |
Chemical Information
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CAS. Nr. 2651234-01-2
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Molecular Weight 427.33
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Formel C22H20Cl2N4O
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SMILES
CC1=CN=C(N)C(/C=C/C2=CN=CC(C(NCCC3=C(Cl)C=C(Cl)C=C3)=O)=C2)=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
GSK190937 Related Classifications
HY-181108 Related Classifications
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