HL389
HL389 inhibits proliferation of cancer cells MDA-MB-231 and MCF-7, with IC50 of 11.39 μM and 9.66 μM. HL389 can be utilized as the ligand for E3 ligase for the synthesis of PROTAC degrader HL435 (HY-161769).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C22H19BrF3NO4
- Molecular Weight:498.29
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
|
Cereblon |
DCAF11 |
Chemical Information
-
Molecular Weight 498.29
-
Formel C22H19BrF3NO4
-
SMILES
BrC(C=C1)=CC(/C=C(C(C=CC(C(F)(F)F)=C2)=C2N3)\C3=O)=C1OCC(OC(C)(C)C)=O
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)