ML189
ML189 is an HSP90 inhibitor. ML189 can be used in the research of infectious diseases such as candidiasis.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 337328-21-9
- Formel: C20H17Cl2N3O
- Molecular Weight:386.27
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
HSP90 |
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| NIH3T3 | IC50 |
21 μM
Compound: 1, ML189
|
Cytotoxicity in mouse NIH/3T3 cells after 48 hrs by Almar blue fluorimetry
Cytotoxicity in mouse NIH/3T3 cells after 48 hrs by Almar blue fluorimetry
|
[PMID: 21802942] |
Chemical Information
-
CAS. Nr. 337328-21-9
-
Molecular Weight 386.27
-
Formel C20H17Cl2N3O
-
SMILES
O=C(C1=CC=C(Cl)C=C1)N2CCN(C3=CC=NC4=CC(Cl)=CC=C34)CC2
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Hartland CL, et al. Identification of small molecules that selectively inhibit fluconazole-resistant Candida albicans in the presence of fluconazole but not in its absence. 2010 Oct 29. [Content Brief]
[2]. Tian J, et al. Overcoming matrix effects: GC method development for the determination of triethylamine and dimethyl sulfoxide in a drug substance. J Chromatogr Sci. 2014 Jan;52(1):36-41. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)