NIP 142
NIP-142 is a benzopyran derivative with multiple ion channel-blocking effects. NIP-142 selectively blocks the potassium ion channels enriched in atrial muscle, prolonging the effective refractory period (ERP) and action potential duration (APD) of the atrium, while having minimal effect on ventricular repolarization. NIP-142 also inhibits L-type/T-type calcium channels and sodium channels, further contributing to its anti-arrhythmic effect. NIP-142 shows significant efficacy in various atrial fibrillation models. NIP-142 can be used for research on arrhythmias.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 203002-58-8
- Formel: C23H27N3O6
- Molecular Weight:441.48
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Alle Calcium Channel Isoform-spezifische Produkte anzeigen
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Biologische Aktivität
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L-type calcium channel |
T-type calcium channel |
Chemical Information
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CAS. Nr. 203002-58-8
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Molecular Weight 441.48
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Formel C23H27N3O6
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SMILES
COC(C=C1)=CC=C1CC(NC2=C([N+]([O-])=O)C=C(OC(C)([C@@H]3O)C)C([C@@H]3NC4CC4)=C2)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
NIP 142 Related Classifications
HY-W705705 Related Classifications
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