- Recombinant Proteins
- CD Antigens
- T Cell CD Proteins NK Cell CD Proteins Macrophage CD Proteins Dendritic Cell CD Proteins
- CD3e
CD3e
CD3e is the epsilon subunit of the CD3 complex, the signal-transducing module noncovalently associated with the T cell antigen receptor. Its cytoplasmic tail carries an ITAM motif that, together with the CD3γ, CD3δ, and ζ-chain ITAMs, initiates ZAP-70 recruitment after antigen engagement. CD3e also stabilizes assembly and surface transport of the TCR-CD3 complex, and murine studies show that anti-CD3e antibodies can modulate T cell responses. The epsilon chain is the target of muromonab (OKT3), the first monoclonal antibody approved for clinical use, and of newer bispecific and tolerogenic anti-CD3 formats. Flow cytometric CD3 antibodies recognize epitopes on CD3e, making it the standard pan-T cell marker.
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CD3e Recombinant Proteins (18)
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- 1
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- 1
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
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