TYK2 activator-2
TYK2 activator-2 (Compound 6g) is a selective TYK2 activator and JAK3 inhibitor, with an EC50 of 0.21 μM against TYK2 and an IC50 of 1.2 μM against JAK3. TYK2 activator-2 destabilizes the JH2-JH1 autoinhibitory complex of TYK2, enhances the catalytic activity of TYK2, and inhibits the JH1 kinase domain activity of JAK3. TYK2 activator-2 can be used in cancer-related research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C28H24FN5O2
- Molecular Weight:481.52
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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Tyk2 0.21 μM (EC50) |
JAK3 1.2 μM (IC50) |
Chemical Information
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Molecular Weight 481.52
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Formel C28H24FN5O2
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SMILES
COC1=C(C#CC2=CC=CC=C2)C=CC=C1NC3=CC(NC4=CC(C)=C(F)C=N4)=NC=C3C(NC)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
TYK2 activator-2 Related Classifications
HY-187211 Related Classifications
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