ATX inhibitor 27
ATX inhibitor 27 (Compound 31) is an ATX inhibitor. The IC50 values of ATX inhibitor 27 against human autotaxin (hATX) and lysophosphatidylcholine (LPC) are 13 nM and 23 nM, respectively. ATX inhibitor 27 reduces LPA levels in vivo by inhibiting ATX enzyme. ATX inhibitor 27 can be used in the study of ATX-LPA-related diseases such as inflammation, neurodegenerative diseases and cancer.
For research use only. We do not sell to patients.
- CAS No.: 2023027-81-6
- Formula: C26H26ClN5O3
- Molecular Weight:491.97
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2023027-81-6
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Molecular Weight 491.97
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Formula C26H26ClN5O3
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SMILES
CC(N1CCC(C2=CC3=C(N=CN(CC(N(C)CC4=CC=C(C#N)C(Cl)=C4)=O)C3=O)C=C2)CC1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)