AURKA-IN-3
AURKA-IN-3 (Compound AL8) is an irreversible covalent Aurora kinase A (AURKA) inhibitor with an IC50 value of 23.0 nM. AURKA-IN-3 inhibits the activation of cAMP signaling pathway and phospholipase C (PLC) signaling pathway mediated by AURKA, and reduces the autophosphorylation level of AURKA. AURKA-IN-3 is promising for research of malignant tumors associated with high AURKA expression (e.g., leukemia, lymphoma).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C38H28ClFN6O6
- Molecular Weight:719.12
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
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Biologische Aktivität
Beschreibung
IC50 & Target
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Aurora A 23.0 nM (IC50) |
Chemical Information
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Molecular Weight 719.12
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Formel C38H28ClFN6O6
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SMILES
O=C(NC1=CC=C(NC2=C(OC)C(C2=O)=O)C=C1)C3=CC=C(NC4=NC=C5C(C6=CC=C(Cl)C=C6C(C7=C(OC)C=CC=C7F)=NC5)=N4)C=C3OC
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
AURKA-IN-3 Related Classifications
HY-175982 Related Classifications
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