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AURKA-IN-3

AURKA-IN-3 (Compound AL8) is an irreversible covalent Aurora kinase A (AURKA) inhibitor with an IC50 value of 23.0 nM. AURKA-IN-3 inhibits the activation of cAMP signaling pathway and phospholipase C (PLC) signaling pathway mediated by AURKA, and reduces the autophosphorylation level of AURKA. AURKA-IN-3 is promising for research of malignant tumors associated with high AURKA expression (e.g., leukemia, lymphoma).

For research use only. We do not sell to patients.

  • Formula: C38H28ClFN6O6
  • Molecular Weight:719.12
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • AURKA-IN-3 Chemical Structure
    AURKA-IN-3 Chemical Structure
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Use of MCE Products

All Aurora Kinase Isoforms

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  • AURKA-IN-3 Chemical Structure
    AURKA-IN-3 Chemical Structure
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  • AURKA-IN-3