BRD4 degrader-5
BRD4 degrader-5 (Compound 23) is a hydrophobic tag (HyTag)-based protein degrader for BRD4 (DC50 = 24.7 μM) through ER stress and autophagy-lysosome pathway. BRD4 degrader-5 inhibits the proliferation of cancer cell 4T1 with an IC50 of 20.6 μM.
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- Formule: C35H42ClN7O2S
- Masse moléculaire:660.27
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Chemical Information
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Masse moléculaire 660.27
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Formule C35H42ClN7O2S
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SMILES
CC1=C(C)C(C(C2=CC=C(Cl)C=C2)=N[C@@H](CC(N3CCN(CC(NC4(C5)C[C@@H]6C[C@@H](C[C@H]5C6)C4)=O)CC3)=O)C7=NN=C(C)N78)=C8S1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BRD4 degrader-5 Related Classifications
HY-170989 Related Classifications
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